21 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	NKX2-5	Homeobox protein Nkx-2.5. (323 aa)
	SIX1	Homeobox protein SIX1. (284 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
	HESX1	Homeobox expressed in ES cells 1 isoform X2. (187 aa)
	SRF	Serum response factor. (464 aa)
	EDNRA	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	MAPK3	Mitogen-activated protein kinase 3. (265 aa)
	NKX2-1	Homeobox protein Nkx-2.1. (296 aa)
	EDN1	Endothelin-1. (202 aa)
	HOXA5	Homeobox protein Hox-A5. (381 aa)
	HOXA3	Homeobox protein Hox-A3 isoform X1. (341 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	HOXD3	LOW QUALITY PROTEIN: homeobox protein Hox-D3. (431 aa)
	SHH	LOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (839 aa)
	PAX8	Paired box protein Pax-8 isoform X1. (458 aa)
	FOXE1	LOW QUALITY PROTEIN: forkhead box protein E1. (331 aa)
	MAPK1	Mitogen-activated protein kinase 1. (263 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	MAP2K1	A0A452CD89	A0A383YTE9	Serine/threonine-protein kinase B-raf.	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.864
BRAF	MAPK1	A0A452CD89	A0A384B9K1	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase 1.	0.833
BRAF	MAPK3	A0A452CD89	A0A384AGR0	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase 3.	0.832
BRAF	PAX8	A0A452CD89	A0A452C5Q0	Serine/threonine-protein kinase B-raf.	Paired box protein Pax-8 isoform X1.	0.424
BRAF	RAF1	A0A452CD89	A0A384AYZ0	Serine/threonine-protein kinase B-raf.	RAF proto-oncogene serine/threonine-protein kinase isoform X1.	0.925
EDN1	EDNRA	A0A383ZGM0	A0A384APZ7	Endothelin-1.	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	EDN1	A0A384APZ7	A0A383ZGM0	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1.	0.999
FGF10	FGF8	A0A384B7G3	A0A384AJG6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.569
FGF10	NKX2-1	A0A384B7G3	A0A384A0N5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein Nkx-2.1.	0.495
FGF10	SHH	A0A384B7G3	A0A452CFB9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.783
FGF8	FGF10	A0A384AJG6	A0A384B7G3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.569
FGF8	SHH	A0A384AJG6	A0A452CFB9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.867
FOXE1	NKX2-1	A0A384BG04	A0A384A0N5	LOW QUALITY PROTEIN: forkhead box protein E1.	Homeobox protein Nkx-2.1.	0.618
FOXE1	PAX8	A0A384BG04	A0A452C5Q0	LOW QUALITY PROTEIN: forkhead box protein E1.	Paired box protein Pax-8 isoform X1.	0.757
HOXA3	HOXA5	A0A383Z958	A0A383Z9K4	Homeobox protein Hox-A3 isoform X1.	Homeobox protein Hox-A5.	0.709
HOXA5	HOXA3	A0A383Z9K4	A0A383Z958	Homeobox protein Hox-A5.	Homeobox protein Hox-A3 isoform X1.	0.709
MAP2K1	BRAF	A0A383YTE9	A0A452CD89	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase B-raf.	0.864
MAP2K1	MAPK1	A0A383YTE9	A0A384B9K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase 1.	0.995
MAP2K1	MAPK3	A0A383YTE9	A0A384AGR0	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase 3.	0.995
MAP2K1	RAF1	A0A383YTE9	A0A384AYZ0	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	RAF proto-oncogene serine/threonine-protein kinase isoform X1.	0.971