(14 nodes) Negative regulation of B cell proliferation network (Balaenoptera acutorostrata)

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second shell of interactors

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Your Input:
	TNFRSF21	Tumor necrosis factor receptor superfamily member 21. (652 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	RC3H1	Roquin-1. (1134 aa)
	IL10	Interleukin-10. (178 aa)
	PAWR	PRKC apoptosis WT1 regulator protein. (338 aa)
	TYROBP	TYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
	LOC103008471	CMRF35-like molecule 8. (310 aa)
	BLK	Tyrosine-protein kinase. (501 aa)
	CTLA4	Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1301 aa)
	PKN1	Serine/threonine-protein kinase N1. (796 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	TNFRSF13B	Tumor necrosis factor receptor superfamily member 13B. (336 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	LYN	A0A384A2D9	A0A383Z0K5	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.969
BTK	TYROBP	A0A384A2D9	A0A452CDL3	Tyrosine-protein kinase.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.486
CTLA4	IL10	A0A384AU34	A0A383Z997	Cytotoxic T-lymphocyte protein 4 isoform X1.	Interleukin-10.	0.551
CTLA4	LYN	A0A384AU34	A0A383Z0K5	Cytotoxic T-lymphocyte protein 4 isoform X1.	Tyrosine-protein kinase.	0.450
IL10	CTLA4	A0A383Z997	A0A384AU34	Interleukin-10.	Cytotoxic T-lymphocyte protein 4 isoform X1.	0.551
INPP5D	LYN	A0A384ACB0	A0A383Z0K5	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein kinase.	0.679
INPP5D	TYROBP	A0A384ACB0	A0A452CDL3	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.460
LOC103008471	TYROBP	A0A452CJJ2	A0A452CDL3	CMRF35-like molecule 8.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.592
LYN	BTK	A0A383Z0K5	A0A384A2D9	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.969
LYN	CTLA4	A0A383Z0K5	A0A384AU34	Tyrosine-protein kinase.	Cytotoxic T-lymphocyte protein 4 isoform X1.	0.450
LYN	INPP5D	A0A383Z0K5	A0A384ACB0	Tyrosine-protein kinase.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	0.679
TYROBP	BTK	A0A452CDL3	A0A384A2D9	TYRO protein tyrosine kinase-binding protein isoform X1.	Tyrosine-protein kinase.	0.486
TYROBP	INPP5D	A0A452CDL3	A0A384ACB0	TYRO protein tyrosine kinase-binding protein isoform X1.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	0.460
TYROBP	LOC103008471	A0A452CDL3	A0A452CJJ2	TYRO protein tyrosine kinase-binding protein isoform X1.	CMRF35-like molecule 8.	0.592