STRINGSTRING
MSX1 MSX1 EN2 EN2 FOXB1 FOXB1 DLG5 DLG5 SOS1 SOS1 EN1 EN1 WNT3A WNT3A RYK RYK FZD6 FZD6 PHOX2A PHOX2A LOC103006469 LOC103006469 WNT9B WNT9B WNT3 WNT3 TAL2 TAL2 WNT1 WNT1 PITX3 PITX3 NDST1 NDST1 SMAD1 SMAD1 OTX1 OTX1 LMX1A LMX1A UCHL5 UCHL5 LOC103001360 LOC103001360 FZD3 FZD3 CTNNB1 CTNNB1 TFAP2D TFAP2D WNT2 WNT2 HES1 HES1 BARHL1 BARHL1 FGF2 FGF2 KAT2A KAT2A LOC103012500 LOC103012500 SHH SHH KDM2B KDM2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSX1Homeobox protein MSX-1. (229 aa)
EN2Homeobox protein engrailed-like. (300 aa)
FOXB1Forkhead box protein B1. (325 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1902 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1001 aa)
EN1Homeobox protein engrailed-like. (206 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
RYKTyrosine-protein kinase RYK. (655 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
PHOX2APaired mesoderm homeobox protein 2A. (218 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
TAL2T-cell acute lymphocytic leukemia protein 2 isoform X1. (127 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PITX3Homeobox protein. (381 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X1. (882 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
OTX1Homeobox protein OTX1 isoform X1. (355 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CTNNB1Catenin beta-1. (767 aa)
TFAP2DTranscription factor AP-2-delta. (452 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HES1Transcription factor HES-1. (280 aa)
BARHL1barH-like 1 homeobox protein. (354 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
KAT2ALOW QUALITY PROTEIN: histone acetyltransferase KAT2A. (839 aa)
LOC103012500LOW QUALITY PROTEIN: histone acetyltransferase KAT2A-like. (732 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
KDM2BLysine-specific demethylase 2B isoform X1. (1223 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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