(50 nodes) Maintenance of protein location in cell network (Balaenoptera acutorostrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PML	Protein PML isoform X1. (871 aa)
	LOC103003549	LOW QUALITY PROTEIN: Golgi phosphoprotein 3-like. (154 aa)
	LOC103018366	Golgi phosphoprotein 3. (86 aa)
	VPS13C	Vacuolar protein sorting-associated protein 13C. (3492 aa)
	LOC114237722	Thymosin beta-4-like. (32 aa)
	DBN1	Drebrin isoform X1. (644 aa)
	HK1	Hexokinase-1 isoform X1. (889 aa)
	TAF8	Transcription initiation factor TFIID subunit 8. (292 aa)
	SYNE1	LOW QUALITY PROTEIN: nesprin-1. (8827 aa)
	LOC103017932	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (46 aa)
	BBS4	Bardet-Biedl syndrome 4 protein isoform X1. (517 aa)
	SORL1	Sortilin-related receptor isoform X1. (2110 aa)
	DZIP1	Zinc finger protein DZIP1 isoform X1. (774 aa)
	HSPA5	Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
	NR5A1	Steroidogenic factor 1. (461 aa)
	CIZ1	Cip1-interacting zinc finger protein isoform X1. (856 aa)
	LOC103021124	Protein RER1-like. (270 aa)
	GOLPH3	Golgi phosphoprotein 3. (272 aa)
	SUPT7L	STAGA complex 65 subunit gamma. (412 aa)
	CCDC88A	Girdin isoform X1. (2026 aa)
	RANGAP1	Ran GTPase-activating protein 1 isoform X1. (585 aa)
	TSPO	Translocator protein. (169 aa)
	KDELR3	ER lumen protein-retaining receptor. (214 aa)
	KDELR2	ER lumen protein-retaining receptor. (150 aa)
	HK2	Hexokinase-2 isoform X1. (1002 aa)
	MORC3	MORC family CW-type zinc finger protein 3. (933 aa)
	PFN4	Profilin; Belongs to the profilin family. (129 aa)
	ANKRD13C	Ankyrin repeat domain-containing protein 13C. (546 aa)
	VPS13A	Vacuolar protein sorting-associated protein 13A isoform X1. (3177 aa)
	LOC103010683	ER lumen protein-retaining receptor. (212 aa)
	OS9	Protein OS-9 isoform X1. (668 aa)
	GSN	Gelsolin isoform X1. (780 aa)
	TOPORS	E3 ubiquitin-protein ligase Topors. (1044 aa)
	TMSB10	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (42 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (405 aa)
	SUN1	SUN domain-containing protein 1 isoform X1. (909 aa)
	ARL2	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	PARK7	Protein/nucleic acid deglycase DJ-1. (189 aa)
	VPS13D	LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 13D. (4397 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
	TWF1	Twinfilin-1 isoform X1. (357 aa)
	KDELR1	ER lumen protein-retaining receptor. (150 aa)
	ARL2BP	ADP-ribosylation factor-like protein 2-binding protein isoform X1. (162 aa)
	TAPT1	Transmembrane anterior posterior transformation protein 1 homolog isoform X2. (462 aa)
	TAF3	Transcription initiation factor TFIID subunit 3. (926 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (798 aa)
	RER1	Protein RER1 isoform X1. (223 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (276 aa)
	CDK5	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
	SCIN	Adseverin. (715 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL2	ARL2BP	A0A383ZGR2	A0A383YXS9	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-like protein 2-binding protein isoform X1.	0.984
ARL2BP	ARL2	A0A383YXS9	A0A383ZGR2	ADP-ribosylation factor-like protein 2-binding protein isoform X1.	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	0.984
ARL2BP	TAPT1	A0A383YXS9	A0A383YXK1	ADP-ribosylation factor-like protein 2-binding protein isoform X1.	Transmembrane anterior posterior transformation protein 1 homolog isoform X2.	0.437
ARL2BP	TOPORS	A0A383YXS9	A0A383ZP76	ADP-ribosylation factor-like protein 2-binding protein isoform X1.	E3 ubiquitin-protein ligase Topors.	0.599
CIZ1	TAF3	A0A384B4V2	A0A383YX83	Cip1-interacting zinc finger protein isoform X1.	Transcription initiation factor TFIID subunit 3.	0.513
GSN	PFN4	A0A383ZSR9	A0A384A820	Gelsolin isoform X1.	Profilin; Belongs to the profilin family.	0.545
GSN	SCIN	A0A383ZSR9	A0A383YQ17	Gelsolin isoform X1.	Adseverin.	0.901
GSN	TWF1	A0A383ZSR9	A0A383Z0H8	Gelsolin isoform X1.	Twinfilin-1 isoform X1.	0.516
HK1	HK2	A0A452C765	A0A384A9W4	Hexokinase-1 isoform X1.	Hexokinase-2 isoform X1.	0.948
HK1	HSPA5	A0A452C765	A0A384B529	Hexokinase-1 isoform X1.	Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.	0.412
HK1	TSPO	A0A452C765	A0A384APB0	Hexokinase-1 isoform X1.	Translocator protein.	0.437
HK2	HK1	A0A384A9W4	A0A452C765	Hexokinase-2 isoform X1.	Hexokinase-1 isoform X1.	0.948
HK2	TSPO	A0A384A9W4	A0A384APB0	Hexokinase-2 isoform X1.	Translocator protein.	0.412
HSPA5	HK1	A0A384B529	A0A452C765	Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.	Hexokinase-1 isoform X1.	0.412
HSPA5	OS9	A0A384B529	A0A383ZX99	Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.	Protein OS-9 isoform X1.	0.621
LOC103017932	PFN4	A0A384BFE7	A0A384A820	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	Profilin; Belongs to the profilin family.	0.527
OS9	HSPA5	A0A383ZX99	A0A384B529	Protein OS-9 isoform X1.	Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.	0.621
PARK7	PINK1	A0A383Z5E6	A0A383ZJ37	Protein/nucleic acid deglycase DJ-1.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.847
PFN4	GSN	A0A384A820	A0A383ZSR9	Profilin; Belongs to the profilin family.	Gelsolin isoform X1.	0.545
PFN4	LOC103017932	A0A384A820	A0A384BFE7	Profilin; Belongs to the profilin family.	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	0.527