(22 nodes) Cholesterol efflux network (Balaenoptera acutorostrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STX12	Syntaxin-12; Belongs to the syntaxin family. (274 aa)
	SPG11	Spatacsin isoform X1. (2437 aa)
	ABCG1	ATP-binding cassette sub-family G member 1 isoform X1. (678 aa)
	TSKU	Tsukushin isoform X1. (367 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (149 aa)
	SOAT2	O-acyltransferase. (535 aa)
	ABCA1	ATP-binding cassette sub-family A member 1 isoform X1. (2264 aa)
	LOC103008831	ATP-binding cassette sub-family A member 1-like. (119 aa)
	ABCA7	ATP-binding cassette sub-family A member 7. (1451 aa)
	SOAT1	O-acyltransferase. (550 aa)
	APOA2	Apolipoprotein A-II isoform X1. (103 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (313 aa)
	APOB	Apolipoprotein B-100. (4585 aa)
	ABCA2	ATP-binding cassette sub-family A member 2. (2133 aa)
	APOA5	Apolipoprotein A-V isoform X1. (378 aa)
	ABCG4	ATP-binding cassette sub-family G member 4 isoform X1. (646 aa)
	APOC3	Apolipoprotein C-III. (99 aa)
	APOA4	Apolipoprotein A-IV. (380 aa)
	APOM	Apolipoprotein M. (188 aa)
	ABCG8	ATP-binding cassette sub-family G member 8. (676 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (652 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (487 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA2	A0A383ZT92	A0A383Z9M2	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein A-II isoform X1.	0.427
ABCA1	APOB	A0A383ZT92	A0A452CHV5	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein B-100.	0.507
ABCA1	SCARB1	A0A383ZT92	A0A384ARF0	ATP-binding cassette sub-family A member 1 isoform X1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.601
ABCA2	APOB	A0A452CHL4	A0A452CHV5	ATP-binding cassette sub-family A member 2.	Apolipoprotein B-100.	0.438
ABCA2	SCARB1	A0A452CHL4	A0A384ARF0	ATP-binding cassette sub-family A member 2.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.525
ABCG1	ABCG5	A0A383ZCJ1	A0A384AS17	ATP-binding cassette sub-family G member 1 isoform X1.	ATP-binding cassette sub-family G member 5.	0.772
ABCG1	APOB	A0A383ZCJ1	A0A452CHV5	ATP-binding cassette sub-family G member 1 isoform X1.	Apolipoprotein B-100.	0.520
ABCG1	SCARB1	A0A383ZCJ1	A0A384ARF0	ATP-binding cassette sub-family G member 1 isoform X1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.709
ABCG4	ABCG5	A0A384BAM0	A0A384AS17	ATP-binding cassette sub-family G member 4 isoform X1.	ATP-binding cassette sub-family G member 5.	0.772
ABCG5	ABCG1	A0A384AS17	A0A383ZCJ1	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 1 isoform X1.	0.772
ABCG5	ABCG4	A0A384AS17	A0A384BAM0	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 4 isoform X1.	0.772
ABCG5	ABCG8	A0A384AS17	A0A384ASQ1	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 8.	0.999
ABCG5	APOB	A0A384AS17	A0A452CHV5	ATP-binding cassette sub-family G member 5.	Apolipoprotein B-100.	0.539
ABCG5	APOC3	A0A384AS17	A0A384BAB1	ATP-binding cassette sub-family G member 5.	Apolipoprotein C-III.	0.421
ABCG5	SCARB1	A0A384AS17	A0A384ARF0	ATP-binding cassette sub-family G member 5.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.648
ABCG8	ABCG5	A0A384ASQ1	A0A384AS17	ATP-binding cassette sub-family G member 8.	ATP-binding cassette sub-family G member 5.	0.999
ABCG8	APOB	A0A384ASQ1	A0A452CHV5	ATP-binding cassette sub-family G member 8.	Apolipoprotein B-100.	0.645
ABCG8	SCARB1	A0A384ASQ1	A0A384ARF0	ATP-binding cassette sub-family G member 8.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.639
APOA2	ABCA1	A0A383Z9M2	A0A383ZT92	Apolipoprotein A-II isoform X1.	ATP-binding cassette sub-family A member 1 isoform X1.	0.427
APOA2	APOA4	A0A383Z9M2	A0A384BAA9	Apolipoprotein A-II isoform X1.	Apolipoprotein A-IV.	0.672