(10 nodes) Low-density lipoprotein particle network (Balaenoptera acutorostrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APOC2	Apolipoprotein C-II. (101 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (313 aa)
	MSR1	Macrophage scavenger receptor types I and II isoform X1. (454 aa)
	APOM	Apolipoprotein M. (188 aa)
	LDLR	Low-density lipoprotein receptor. (842 aa)
	SELENOS	Selenoprotein S isoform X1. (203 aa)
	APOB	Apolipoprotein B-100. (4585 aa)
	APOBR	Apolipoprotein B receptor. (1013 aa)
	APOO	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (198 aa)
	PLA2G7	Platelet-activating factor acetylhydrolase. (444 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	APOBR	A0A452CHV5	A0A452CK30	Apolipoprotein B-100.	Apolipoprotein B receptor.	0.525
APOB	APOC2	A0A452CHV5	A0A383YZ74	Apolipoprotein B-100.	Apolipoprotein C-II.	0.834
APOB	APOE	A0A452CHV5	P0DML7	Apolipoprotein B-100.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.797
APOB	APOM	A0A452CHV5	A0A384B3X2	Apolipoprotein B-100.	Apolipoprotein M.	0.599
APOB	LDLR	A0A452CHV5	A0A452C822	Apolipoprotein B-100.	Low-density lipoprotein receptor.	0.971
APOB	MSR1	A0A452CHV5	A0A383ZG86	Apolipoprotein B-100.	Macrophage scavenger receptor types I and II isoform X1.	0.631
APOBR	APOB	A0A452CK30	A0A452CHV5	Apolipoprotein B receptor.	Apolipoprotein B-100.	0.525
APOC2	APOB	A0A383YZ74	A0A452CHV5	Apolipoprotein C-II.	Apolipoprotein B-100.	0.834
APOC2	APOE	A0A383YZ74	P0DML7	Apolipoprotein C-II.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.909
APOC2	APOM	A0A383YZ74	A0A384B3X2	Apolipoprotein C-II.	Apolipoprotein M.	0.460
APOE	APOB	P0DML7	A0A452CHV5	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Apolipoprotein B-100.	0.797
APOE	APOC2	P0DML7	A0A383YZ74	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Apolipoprotein C-II.	0.909
APOM	APOB	A0A384B3X2	A0A452CHV5	Apolipoprotein M.	Apolipoprotein B-100.	0.599
APOM	APOC2	A0A384B3X2	A0A383YZ74	Apolipoprotein M.	Apolipoprotein C-II.	0.460
LDLR	APOB	A0A452C822	A0A452CHV5	Low-density lipoprotein receptor.	Apolipoprotein B-100.	0.971
MSR1	APOB	A0A383ZG86	A0A452CHV5	Macrophage scavenger receptor types I and II isoform X1.	Apolipoprotein B-100.	0.631