(98 nodes) Centriolar satellite network (Balaenoptera acutorostrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAF1D	LOW QUALITY PROTEIN: TATA box-binding protein-associated factor RNA polymerase I subunit D. (321 aa)
	CHD3	chromodomain-helicase-DNA-binding protein 3 isoform X1. (1888 aa)
	KLHL12	Kelch-like protein 12 isoform X2. (684 aa)
	KNSTRN	LOW QUALITY PROTEIN: small kinetochore-associated protein. (313 aa)
	BBS9	Protein PTHB1 isoform X1. (896 aa)
	C2CD3	C2 domain-containing protein 3 isoform X1. (2349 aa)
	SSX2IP	Afadin- and alpha-actinin-binding protein isoform X1. (618 aa)
	ODF2L	Protein BCAP isoform X4. (643 aa)
	LOC103019618	LOW QUALITY PROTEIN: afadin- and alpha-actinin-binding protein-like. (617 aa)
	PARD6A	Partitioning defective 6 homolog alpha. (345 aa)
	BBS4	Bardet-Biedl syndrome 4 protein isoform X1. (517 aa)
	RPP25	Ribonuclease P protein subunit p25. (213 aa)
	KCTD1	BTB/POZ domain-containing protein KCTD1 isoform X1. (265 aa)
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	SKA1	Spindle and kinetochore-associated protein 1. (255 aa)
	DCDC2	Doublecortin domain-containing protein 2. (473 aa)
	DZIP1	Zinc finger protein DZIP1 isoform X1. (774 aa)
	KIF5B	Kinesin-1 heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1036 aa)
	CEP162	Centrosomal protein of 162 kDa. (1405 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1. (200 aa)
	C2CD5	C2 domain-containing protein 5 isoform X1. (1075 aa)
	RASSF8	Ras association domain-containing protein 8. (419 aa)
	NEK6	Serine/threonine-protein kinase Nek6 isoform X1; Belongs to the protein kinase superfamily. (365 aa)
	DBH	Dopamine beta-hydroxylase. (610 aa)
	CD2AP	CD2-associated protein. (714 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
	CCDC13	Coiled-coil domain-containing protein 13. (762 aa)
	RBM39	RNA-binding protein 39 isoform X1. (530 aa)
	DLGAP5	Disks large-associated protein 5. (846 aa)
	NEK1	Serine/threonine-protein kinase Nek1 isoform X4. (1280 aa)
	CCDC66	Coiled-coil domain-containing protein 66 isoform X1. (986 aa)
	PXK	PX domain-containing protein kinase-like protein isoform X7. (570 aa)
	PDZD2	PDZ domain-containing protein 2. (2580 aa)
	AK5	Adenylate kinase isoenzyme 5 isoform X1; Belongs to the adenylate kinase family. (561 aa)
	CEP68	Centrosomal protein of 68 kDa isoform X1. (760 aa)
	LOC102998388	Keratin, type I cytoskeletal 18-like; Belongs to the intermediate filament family. (472 aa)
	PLA2G6	85/88 kDa calcium-independent phospholipase A2 isoform X1. (806 aa)
	FOPNL	lisH domain-containing protein FOPNL isoform X1. (174 aa)
	KLHL4	LOW QUALITY PROTEIN: kelch-like protein 4. (718 aa)
	PAX2	Paired box protein Pax-2 isoform X1. (463 aa)
	LOC103020725	T-cell receptor-associated transmembrane adapter 1. (186 aa)
	TAP1	Antigen peptide transporter 1 isoform X1. (768 aa)
	MAP11	Uncharacterized protein C7orf43 homolog. (571 aa)
	IL4R	Interleukin-4 receptor subunit alpha isoform X1. (832 aa)
	PLK1	Serine/threonine-protein kinase PLK. (604 aa)
	PIBF1	Progesterone-induced-blocking factor 1 isoform X1. (757 aa)
	GPR174	Probable G-protein coupled receptor 174. (333 aa)
	CEP131	Centrosomal protein of 131 kDa. (1090 aa)
	EXOC7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa)
	ZBED6CL	LOW QUALITY PROTEIN: ZBED6 C-terminal-like protein. (322 aa)
	MPP1	55 kDa erythrocyte membrane protein; Belongs to the MAGUK family. (490 aa)
	G6PD	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (631 aa)
	IFT43	Intraflagellar transport protein 43 homolog isoform X1. (207 aa)
	FNIP2	Folliculin-interacting protein 2. (838 aa)
	RAB11FIP5	Rab11 family-interacting protein 5 isoform X1. (1205 aa)
	SPAG5	Sperm-associated antigen 5. (1180 aa)
	RSKR	LOW QUALITY PROTEIN: ribosomal protein S6 kinase-related protein. (406 aa)
	BBS5	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
	LOC103010096	PX domain-containing protein kinase-like protein. (105 aa)
	SDCCAG8	Serologically defined colon cancer antigen 8 isoform X1. (697 aa)
	MID1	E3 ubiquitin-protein ligase Midline-1 isoform X1. (677 aa)
	RAB11FIP3	Rab11 family-interacting protein 3. (473 aa)
	NLRC3	NLR family CARD domain-containing protein 3. (1065 aa)
	UBN1	Ubinuclein-1 isoform X1. (1134 aa)
	WDR13	WD repeat-containing protein 13. (491 aa)
	KRT18	Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (429 aa)
	HOOK3	Protein Hook homolog 3 isoform X1. (680 aa)
	UPF3B	Regulator of nonsense transcripts 3B isoform X1. (483 aa)
	DDHD2	Phospholipase DDHD2. (715 aa)
	CENPU	Centromere protein U isoform X1. (411 aa)
	MIEN1	Migration and invasion enhancer 1. (115 aa)
	KIAA0753	Protein moonraker isoform X1. (910 aa)
	TEK	Angiopoietin-1 receptor isoform X1. (1125 aa)
	SPAG9	C-Jun-amino-terminal kinase-interacting protein 4 isoform X1. (1338 aa)
	CCDC14	Coiled-coil domain-containing protein 14. (898 aa)
	DYSF	Dysferlin isoform X1. (2152 aa)
	NR0B1	LOW QUALITY PROTEIN: nuclear receptor subfamily 0 group B member 1. (463 aa)
	NAA40	N-alpha-acetyltransferase 40. (216 aa)
	FLII	Protein flightless-1 homolog isoform X1. (1247 aa)
	PCM1	Pericentriolar material 1 protein isoform X1. (2123 aa)
	RASSF7	Ras association domain-containing protein 7. (359 aa)
	BBS1	Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
	FRMD8	FERM domain-containing protein 8 isoform X1. (465 aa)
	YTHDF2	YTH domain-containing family protein 2. (546 aa)
	LRIF1	Ligand-dependent nuclear receptor-interacting factor 1 isoform X1. (762 aa)
	KEAP1	Kelch-like ECH-associated protein 1. (624 aa)
	ZMYND10	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
	CCDC61	Coiled-coil domain-containing protein 61. (503 aa)
	NUDT21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (230 aa)
	CCDC113	Coiled-coil domain-containing protein 113. (377 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	TMEM63A	CSC1-like protein 1 isoform X1. (804 aa)
	PIK3R5	Phosphoinositide 3-kinase regulatory subunit 5. (882 aa)
	RAB11A	Ras-related protein Rab-11A. (216 aa)
	CYTH4	Cytohesin-4. (423 aa)
	WDR62	WD repeat-containing protein 62. (1546 aa)
	PATJ	inaD-like protein isoform X1. (1903 aa)
	LATS2	Serine/threonine-protein kinase LATS2. (795 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS1	BBS4	A0A383Z7R2	A0A384BDQ0	Bardet-Biedl syndrome 1 protein isoform X1.	Bardet-Biedl syndrome 4 protein isoform X1.	0.999
BBS1	BBS5	A0A383Z7R2	A0A384A7G1	Bardet-Biedl syndrome 1 protein isoform X1.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.999
BBS1	BBS9	A0A383Z7R2	A0A452CC84	Bardet-Biedl syndrome 1 protein isoform X1.	Protein PTHB1 isoform X1.	0.999
BBS1	CEP131	A0A383Z7R2	A0A384AF70	Bardet-Biedl syndrome 1 protein isoform X1.	Centrosomal protein of 131 kDa.	0.424
BBS1	IFT43	A0A383Z7R2	A0A384AB46	Bardet-Biedl syndrome 1 protein isoform X1.	Intraflagellar transport protein 43 homolog isoform X1.	0.525
BBS1	KEAP1	A0A383Z7R2	A0A383Z1K8	Bardet-Biedl syndrome 1 protein isoform X1.	Kelch-like ECH-associated protein 1.	0.541
BBS1	KLHL4	A0A383Z7R2	A0A384AK48	Bardet-Biedl syndrome 1 protein isoform X1.	LOW QUALITY PROTEIN: kelch-like protein 4.	0.541
BBS1	PCM1	A0A383Z7R2	A0A383ZG47	Bardet-Biedl syndrome 1 protein isoform X1.	Pericentriolar material 1 protein isoform X1.	0.452
BBS1	SDCCAG8	A0A383Z7R2	A0A384A564	Bardet-Biedl syndrome 1 protein isoform X1.	Serologically defined colon cancer antigen 8 isoform X1.	0.409
BBS4	BBS1	A0A384BDQ0	A0A383Z7R2	Bardet-Biedl syndrome 4 protein isoform X1.	Bardet-Biedl syndrome 1 protein isoform X1.	0.999
BBS4	BBS5	A0A384BDQ0	A0A384A7G1	Bardet-Biedl syndrome 4 protein isoform X1.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.994
BBS4	BBS9	A0A384BDQ0	A0A452CC84	Bardet-Biedl syndrome 4 protein isoform X1.	Protein PTHB1 isoform X1.	0.999
BBS4	CCDC13	A0A384BDQ0	A0A384B1M4	Bardet-Biedl syndrome 4 protein isoform X1.	Coiled-coil domain-containing protein 13.	0.400
BBS4	CCDC66	A0A384BDQ0	A0A384AYG3	Bardet-Biedl syndrome 4 protein isoform X1.	Coiled-coil domain-containing protein 66 isoform X1.	0.422
BBS4	CEP131	A0A384BDQ0	A0A384AF70	Bardet-Biedl syndrome 4 protein isoform X1.	Centrosomal protein of 131 kDa.	0.536
BBS4	IFT43	A0A384BDQ0	A0A384AB46	Bardet-Biedl syndrome 4 protein isoform X1.	Intraflagellar transport protein 43 homolog isoform X1.	0.454
BBS4	KEAP1	A0A384BDQ0	A0A383Z1K8	Bardet-Biedl syndrome 4 protein isoform X1.	Kelch-like ECH-associated protein 1.	0.533
BBS4	KLHL4	A0A384BDQ0	A0A384AK48	Bardet-Biedl syndrome 4 protein isoform X1.	LOW QUALITY PROTEIN: kelch-like protein 4.	0.533
BBS4	PCM1	A0A384BDQ0	A0A383ZG47	Bardet-Biedl syndrome 4 protein isoform X1.	Pericentriolar material 1 protein isoform X1.	0.856
BBS4	SDCCAG8	A0A384BDQ0	A0A384A564	Bardet-Biedl syndrome 4 protein isoform X1.	Serologically defined colon cancer antigen 8 isoform X1.	0.401