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CACNG2 CACNG2 TMEM249 TMEM249 MCU MCU CACNA2D2 CACNA2D2 CATSPERD CATSPERD RYR2 RYR2 CATSPERZ CATSPERZ MICU2 MICU2 CACHD1 CACHD1 SCN5A SCN5A TRPC4 TRPC4 CATSPERG CATSPERG PTPA PTPA CACNB2 CACNB2 CATSPER2 CATSPER2 CACNA1S CACNA1S MICU1 MICU1 CACNB1 CACNB1 CACNA1C CACNA1C CACNG7 CACNG7 PKD1 PKD1 CACNA1A CACNA1A CACNA1B CACNA1B PKD2L1 PKD2L1 CACNA1E CACNA1E CACNA1I CACNA1I CACNB3 CACNB3 TRPC5 TRPC5 CACNB4 CACNB4 SCN8A SCN8A CACNA2D1 CACNA2D1 CATSPER4 CATSPER4 SCN9A SCN9A CACNA2D4 CACNA2D4 CACNA1G CACNA1G PDE4D PDE4D CACNA1D CACNA1D CACNA2D3 CACNA2D3 PDE4B PDE4B TMEM262 TMEM262 AKAP6 AKAP6 CATSPERB CATSPERB CACNG6 CACNG6 CACNA1H CACNA1H CATSPERE CATSPERE CACNA1F CACNA1F LOC102998353 LOC102998353 FKBP1B FKBP1B HSPA2 HSPA2 TRPV5 TRPV5 TRPV6 TRPV6 CACNG5 CACNG5 MICU3 MICU3 CATSPER3 CATSPER3 CATSPER1 CATSPER1 EFCAB9 EFCAB9 CACNG1 CACNG1 CACNG4 CACNG4 LOC103010313 LOC103010313 SMDT1 SMDT1 SESTD1 SESTD1 MCUB MCUB SCN11A SCN11A
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
TMEM249Transmembrane protein 249. (241 aa)
MCUCalcium uniporter protein, mitochondrial. (348 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1075 aa)
CATSPERDCation channel sperm-associated protein subunit delta. (614 aa)
RYR2Ryanodine receptor 2 isoform X1. (4884 aa)
CATSPERZCation channel sperm-associated protein subunit zeta isoform X1. (209 aa)
MICU2Calcium uptake protein 2, mitochondrial. (364 aa)
CACHD1VWFA and cache domain-containing protein 1. (1258 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1992 aa)
TRPC4Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
CATSPERGCation channel sperm-associated protein subunit gamma isoform X1. (1156 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (288 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa)
CATSPER2LOW QUALITY PROTEIN: cation channel sperm-associated protein 2. (529 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
MICU1Calcium uptake protein 1, mitochondrial. (484 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform X4. (617 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (282 aa)
PKD1LOW QUALITY PROTEIN: polycystin-1. (4200 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2153 aa)
PKD2L1LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein. (683 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2331 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2076 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3. (539 aa)
TRPC5Short transient receptor potential channel 5. (640 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (502 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1110 aa)
CATSPER4Cation channel sperm-associated protein 4. (450 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1108 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
PDE4DPhosphodiesterase. (776 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3. (1091 aa)
PDE4BPhosphodiesterase. (736 aa)
TMEM262Transmembrane protein 262 isoform X1. (116 aa)
AKAP6A-kinase anchor protein 6 isoform X1. (2322 aa)
CATSPERBCation channel sperm-associated protein subunit beta. (1132 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
CACNA1HLOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2326 aa)
CATSPERECation channel sperm-associated protein subunit epsilon. (773 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC102998353Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (731 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6 isoform X3; Belongs to the transient receptor (TC 1.A.4) family. (721 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
MICU3Calcium uptake protein 3, mitochondrial. (533 aa)
CATSPER3Cation channel sperm-associated protein 3. (400 aa)
CATSPER1Cation channel sperm-associated protein 1. (677 aa)
EFCAB9EF-hand calcium-binding domain-containing protein 9. (189 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit. (549 aa)
LOC103010313Short transient receptor potential channel 5-like. (302 aa)
SMDT1Essential MCU regulator, mitochondrial. (107 aa)
SESTD1SEC14 domain and spectrin repeat-containing protein 1 isoform X1. (696 aa)
MCUBLOW QUALITY PROTEIN: calcium uniporter regulatory subunit MCUb, mitochondrial. (334 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1784 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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