STRINGSTRING
ATF2 ATF2 MATN1 MATN1 FGF7 FGF7 S1PR1 S1PR1 PLAG1 PLAG1 STK3 STK3 ZMPSTE24 ZMPSTE24 LEPR LEPR FGF9 FGF9 GJE1 GJE1 HLX HLX PSAPL1 PSAPL1 TGFB2 TGFB2 RARB RARB JARID2 JARID2 CER1 CER1 BNC2 BNC2 RARA RARA ECM1 ECM1 TMEM38B TMEM38B THBS3 THBS3 ARID2 ARID2 UBE3A UBE3A RARG RARG RAG2 RAG2 ADPRH ADPRH FXN FXN HEG1 HEG1 IL7 IL7 AR AR PRKAR1A PRKAR1A SOX9 SOX9 DLL1 DLL1 SPRY2 SPRY2 FGF8 FGF8 TENM4 TENM4 ANXA6 ANXA6 EXT1 EXT1 MAPK11 MAPK11 SMAD1 SMAD1 BMP10 BMP10 TBX5 TBX5 HEY2 HEY2 EVC EVC DDR2 DDR2 MMP13 MMP13 BCL2 BCL2 ADRA1A ADRA1A SAV1 SAV1 STK4 STK4 EHMT2 EHMT2 LOC103015737 LOC103015737 WNT2 WNT2 OSTN OSTN FGF10 FGF10 COMP COMP ADPRHL1 ADPRHL1 GATA6 GATA6 SMPD3 SMPD3 NOTCH1 NOTCH1 ESR1 ESR1 LOC103001916 LOC103001916 LOC114235831 LOC114235831 ANKRD26 ANKRD26 PTPN11 PTPN11 LEP LEP SHH SHH ARX ARX LOC103016806 LOC103016806 IFT80 IFT80 DIPK2A DIPK2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
MATN1Cartilage matrix protein. (495 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
STK3Serine/threonine-protein kinase 3. (487 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
LEPRLeptin receptor isoform X4. (1166 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GJE1Putative gap junction epsilon-1 protein isoform X1. (210 aa)
HLXH2.0-like homeobox protein. (442 aa)
PSAPL1LOW QUALITY PROTEIN: proactivator polypeptide-like 1. (533 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
RARBRetinoic acid receptor beta. (584 aa)
JARID2Protein Jumonji. (1235 aa)
CER1Cerberus. (273 aa)
BNC2Zinc finger protein basonuclin-2 isoform X1. (1043 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
ECM1Extracellular matrix protein 1 isoform X1. (543 aa)
TMEM38BTrimeric intracellular cation channel type B. (292 aa)
THBS3LOW QUALITY PROTEIN: thrombospondin-3. (956 aa)
ARID2AT-rich interactive domain-containing protein 2. (1687 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
RAG2V(D)J recombination-activating protein 2. (527 aa)
ADPRHADP-ribosylarginine hydrolase. (362 aa)
FXNFrataxin, mitochondrial. (239 aa)
HEG1Protein HEG homolog 1. (1339 aa)
IL7Interleukin-7 isoform X2. (178 aa)
ARAndrogen receptor isoform X1. (895 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
SOX9Transcription factor SOX-9. (432 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
TENM4Teneurin-4. (2739 aa)
ANXA6Annexin. (673 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
MAPK11Mitogen-activated protein kinase. (281 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
TBX5T-box transcription factor TBX5 isoform X1. (536 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
EVCEllis-van Creveld syndrome protein. (1044 aa)
DDR2Discoidin domain-containing receptor 2. (855 aa)
MMP13Collagenase 3. (471 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
ADRA1Aalpha-1A adrenergic receptor isoform X1. (466 aa)
SAV1Protein salvador homolog 1. (351 aa)
STK4Serine/threonine-protein kinase 4. (411 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
LOC103015737Mesoderm posterior protein 1. (126 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
OSTNOsteocrin isoform X1. (138 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
COMPCartilage oligomeric matrix protein. (658 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1 isoform X1. (359 aa)
GATA6Transcription factor GATA-6. (357 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
ESR1LOW QUALITY PROTEIN: estrogen receptor. (422 aa)
LOC103001916LOW QUALITY PROTEIN: serine/threonine-protein kinase 3-like. (366 aa)
LOC114235831Estrogen receptor-like. (144 aa)
ANKRD26Ankyrin repeat domain-containing protein 26 isoform X1. (2071 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
ARXHomeobox protein ARX. (121 aa)
LOC103016806LOW QUALITY PROTEIN: retinoic acid receptor beta-like. (358 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (808 aa)
DIPK2ADivergent protein kinase domain 2A isoform X1. (432 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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