(7 nodes) Derlin-1 retrotranslocation complex network (Balaenoptera acutorostrata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	AMFR	E3 ubiquitin-protein ligase AMFR. (548 aa)
	SYVN1	E3 ubiquitin-protein ligase synoviolin. (610 aa)
	SEL1L	Protein sel-1 homolog 1. (794 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
	RNF139	E3 ubiquitin-protein ligase RNF139 isoform X1. (664 aa)
	SELENOS	Selenoprotein S isoform X1. (203 aa)
	HM13	Minor histocompatibility antigen H13 isoform X1. (449 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	A0A383YY91	A0A384ANK5	E3 ubiquitin-protein ligase AMFR.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.991
AMFR	SEL1L	A0A383YY91	A0A384AN22	E3 ubiquitin-protein ligase AMFR.	Protein sel-1 homolog 1.	0.855
AMFR	SYVN1	A0A383YY91	A0A383Z7Z7	E3 ubiquitin-protein ligase AMFR.	E3 ubiquitin-protein ligase synoviolin.	0.528
DERL1	AMFR	A0A384ANK5	A0A383YY91	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	E3 ubiquitin-protein ligase AMFR.	0.991
DERL1	HM13	A0A384ANK5	A0A452CQ92	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Minor histocompatibility antigen H13 isoform X1.	0.589
DERL1	RNF139	A0A384ANK5	A0A384AP24	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	E3 ubiquitin-protein ligase RNF139 isoform X1.	0.734
DERL1	SEL1L	A0A384ANK5	A0A384AN22	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Protein sel-1 homolog 1.	0.943
DERL1	SELENOS	A0A384ANK5	A0A452CET4	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Selenoprotein S isoform X1.	0.841
DERL1	SYVN1	A0A384ANK5	A0A383Z7Z7	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	E3 ubiquitin-protein ligase synoviolin.	0.960
HM13	DERL1	A0A452CQ92	A0A384ANK5	Minor histocompatibility antigen H13 isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.589
HM13	RNF139	A0A452CQ92	A0A384AP24	Minor histocompatibility antigen H13 isoform X1.	E3 ubiquitin-protein ligase RNF139 isoform X1.	0.554
RNF139	DERL1	A0A384AP24	A0A384ANK5	E3 ubiquitin-protein ligase RNF139 isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.734
RNF139	HM13	A0A384AP24	A0A452CQ92	E3 ubiquitin-protein ligase RNF139 isoform X1.	Minor histocompatibility antigen H13 isoform X1.	0.554
RNF139	SEL1L	A0A384AP24	A0A384AN22	E3 ubiquitin-protein ligase RNF139 isoform X1.	Protein sel-1 homolog 1.	0.728
SEL1L	AMFR	A0A384AN22	A0A383YY91	Protein sel-1 homolog 1.	E3 ubiquitin-protein ligase AMFR.	0.855
SEL1L	DERL1	A0A384AN22	A0A384ANK5	Protein sel-1 homolog 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.943
SEL1L	RNF139	A0A384AN22	A0A384AP24	Protein sel-1 homolog 1.	E3 ubiquitin-protein ligase RNF139 isoform X1.	0.728
SEL1L	SYVN1	A0A384AN22	A0A383Z7Z7	Protein sel-1 homolog 1.	E3 ubiquitin-protein ligase synoviolin.	0.963
SELENOS	DERL1	A0A452CET4	A0A384ANK5	Selenoprotein S isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.841
SELENOS	SYVN1	A0A452CET4	A0A383Z7Z7	Selenoprotein S isoform X1.	E3 ubiquitin-protein ligase synoviolin.	0.455