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LOC103012696 LOC103012696 RLIM RLIM LOC103008965 LOC103008965 TNP1 TNP1 PCGF5 PCGF5 HELLS HELLS RB1 RB1 MECP2 MECP2 ZNF335 ZNF335 ZNFX1 ZNFX1 PRDM14 PRDM14 EZH2 EZH2 SMYD5 SMYD5 CHEK1 CHEK1 HAT1 HAT1 RIF1 RIF1 PHF2 PHF2 AXIN1 AXIN1 PCGF3 PCGF3 CTBP1 CTBP1 BAHD1 BAHD1 METTL3 METTL3 HDAC5 HDAC5 SUV39H1 SUV39H1 BAZ2A BAZ2A HMGA2 HMGA2 SMARCD1 SMARCD1 TRIM27 TRIM27 VPS72 VPS72 LOC103015379 LOC103015379 LOC103008156 LOC103008156 LOC103020966 LOC103020966 MBD3 MBD3 LMNB2 LMNB2 LOC103011144 LOC103011144 LOC103012673 LOC103012673 SPTY2D1 SPTY2D1 CENPV CENPV CDYL CDYL JARID2 JARID2 DNMT3L DNMT3L RRP8 RRP8 LOC103002265 LOC103002265 LMNA LMNA KCNQ1 KCNQ1 HDAC1 HDAC1 EXOSC10 EXOSC10 GLMN GLMN RBM15 RBM15 LRIF1 LRIF1 SIRT6 SIRT6 LOC102997638 LOC102997638 CREBZF CREBZF GSK3A GSK3A PPHLN1 PPHLN1 SPHK2 SPHK2 SIRT1 SIRT1 LOC103019059 LOC103019059 NDN NDN LOC103000311 LOC103000311 HNRNPU HNRNPU FAM47E FAM47E LOC103018221 LOC103018221 CGGBP1 CGGBP1 ARID4A ARID4A ASIP ASIP YTHDC1 YTHDC1 NRM NRM LOC103010562 LOC103010562 EPC1 EPC1 LOC114238459 LOC114238459 MORC1 MORC1 EP300 EP300 MBD2 MBD2 FAM172A FAM172A KDM1B KDM1B UBR2 UBR2 CTCF CTCF PRMT7 PRMT7 POLE3 POLE3 LHX2 LHX2 MBD3L1 MBD3L1 DOT1L DOT1L DNMT1 DNMT1 MORC2 MORC2 ZFP57 ZFP57 HDAC6 HDAC6 KLF2 KLF2 TFAP2C TFAP2C CTCFL CTCFL WBP2 WBP2 LOC103003515 LOC103003515 LMNB1 LMNB1 SMARCA5 SMARCA5 BMI1 BMI1 SUZ12 SUZ12 PPM1D PPM1D ZDBF2 ZDBF2 BEND3 BEND3 DNMT3A DNMT3A SMCHD1 SMCHD1 TASOR TASOR LOC103017898 LOC103017898
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103012696E3 ubiquitin-protein ligase RLIM. (605 aa)
RLIME3 ubiquitin-protein ligase RLIM. (623 aa)
LOC103008965prelamin-A/C-like; Belongs to the intermediate filament family. (103 aa)
TNP1Spermatid nuclear transition protein 1. (55 aa)
PCGF5Polycomb group RING finger protein 5 isoform X1. (256 aa)
HELLSLOW QUALITY PROTEIN: lymphoid-specific helicase. (875 aa)
RB1Retinoblastoma-associated protein. (816 aa)
MECP2methyl-CpG-binding protein 2. (459 aa)
ZNF335Zinc finger protein 335 isoform X1. (1343 aa)
ZNFX1NFX1-type zinc finger-containing protein 1 isoform X1. (1918 aa)
PRDM14PR domain zinc finger protein 14. (571 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (746 aa)
SMYD5SET and MYND domain-containing protein 5 isoform X1. (309 aa)
CHEK1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
RIF1Telomere-associated protein RIF1 isoform X1. (2467 aa)
PHF2Lysine-specific demethylase PHF2. (981 aa)
AXIN1Axin-1 isoform X1. (866 aa)
PCGF3Polycomb group RING finger protein 3 isoform X1. (242 aa)
CTBP1LOW QUALITY PROTEIN: C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa)
BAHD1Bromo adjacent homology domain-containing 1 protein isoform X1. (779 aa)
METTL3N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1138 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
BAZ2ABromodomain adjacent to zinc finger domain protein 2A isoform X1. (1911 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
SMARCD1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1. (476 aa)
TRIM27LOW QUALITY PROTEIN: zinc finger protein RFP. (517 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog isoform X1. (364 aa)
LOC103015379Histone-lysine N-methyltransferase EZH1 isoform X1. (747 aa)
LOC103008156Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (765 aa)
LOC103020966Histone-lysine N-methyltransferase EZH1 isoform X2. (744 aa)
MBD3methyl-CpG-binding domain protein 3. (233 aa)
LMNB2lamin-B2; Belongs to the intermediate filament family. (544 aa)
LOC103011144Histone H3.3-like. (136 aa)
LOC103012673Protein-arginine deiminase type-2. (647 aa)
SPTY2D1Protein SPT2 homolog. (728 aa)
CENPVCentromere protein V. (184 aa)
CDYLChromodomain Y-like protein. (585 aa)
JARID2Protein Jumonji. (1235 aa)
DNMT3LDNA (Cytosine-5)-methyltransferase 3-like. (417 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (458 aa)
LOC103002265Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LMNALamin; Belongs to the intermediate filament family. (664 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
EXOSC10LOW QUALITY PROTEIN: exosome component 10. (887 aa)
GLMNGlomulin isoform X1. (592 aa)
RBM15RNA-binding protein 15. (962 aa)
LRIF1Ligand-dependent nuclear receptor-interacting factor 1 isoform X1. (762 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
LOC102997638DNA (Cytosine-5)-methyltransferase 1-like. (185 aa)
CREBZFCREB/ATF bZIP transcription factor. (355 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (410 aa)
PPHLN1Periphilin-1 isoform X1. (387 aa)
SPHK2Sphingosine kinase 2 isoform X1. (665 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
LOC103019059Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
NDNNecdin. (325 aa)
LOC103000311Histone H3; Belongs to the histone H3 family. (136 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (798 aa)
FAM47EProtein FAM47E. (389 aa)
LOC103018221Uncharacterized protein. (440 aa)
CGGBP1CGG triplet repeat-binding protein 1. (167 aa)
ARID4AAT-rich interactive domain-containing protein 4A. (1259 aa)
ASIPAgouti-signaling protein. (171 aa)
YTHDC1YTH domain-containing protein 1 isoform X1. (744 aa)
NRMNurim isoform X1. (262 aa)
LOC103010562Histone H3; Belongs to the histone H3 family. (136 aa)
EPC1Enhancer of polycomb homolog. (842 aa)
LOC114238459Histone H3.3-like. (127 aa)
MORC1LOW QUALITY PROTEIN: MORC family CW-type zinc finger protein 1. (991 aa)
EP300Histone acetyltransferase p300. (2445 aa)
MBD2methyl-CpG-binding domain protein 2. (262 aa)
FAM172ACotranscriptional regulator FAM172A isoform X1. (416 aa)
KDM1BLysine-specific histone demethylase 1B isoform X1. (820 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa)
CTCFTranscriptional repressor CTCF isoform X1. (727 aa)
PRMT7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (729 aa)
POLE3LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 3. (146 aa)
LHX2LOW QUALITY PROTEIN: LIM/homeobox protein Lhx2. (406 aa)
MBD3L1LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 3-like 1. (192 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1548 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1348 aa)
MORC2MORC family CW-type zinc finger protein 2. (1015 aa)
ZFP57Zinc finger protein 57 homolog. (602 aa)
HDAC6Histone deacetylase 6. (1143 aa)
KLF2Krueppel-like factor 2. (181 aa)
TFAP2CTranscription factor AP-2 gamma isoform X2. (452 aa)
CTCFLTranscriptional repressor CTCFL isoform X1. (639 aa)
WBP2WW domain-binding protein 2 isoform X1. (261 aa)
LOC103003515LOW QUALITY PROTEIN: histone H1oo-like. (304 aa)
LMNB1lamin-B1; Belongs to the intermediate filament family. (591 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
SUZ12Polycomb protein SUZ12. (694 aa)
PPM1DLOW QUALITY PROTEIN: protein phosphatase 1D. (605 aa)
ZDBF2DBF4-type zinc finger-containing protein 2. (2441 aa)
BEND3BEN domain-containing protein 3. (828 aa)
DNMT3ADNA (Cytosine-5)-methyltransferase 3A; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (910 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (1972 aa)
TASORProtein TASOR isoform X1. (1672 aa)
LOC103017898Histone H1oo. (349 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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