STRINGSTRING
STIM1 STIM1 WNT6 WNT6 LOC103002330 LOC103002330 FAM20A FAM20A LAMA5 LAMA5 EDA EDA HAND1 HAND1 KLK4 KLK4 KLK5 KLK5 SHH SHH SMO SMO COL1A1 COL1A1 SRC SRC BMP4 BMP4 CTNNB1 CTNNB1 ENAM ENAM AMBN AMBN ODAM ODAM RUNX2 RUNX2 WDR72 WDR72 CFTR CFTR FGF10 FGF10 FST FST CNNM4 CNNM4 BCL2L11 BCL2L11 SMPD3 SMPD3 AMTN AMTN TP63 TP63 TGFB1 TGFB1 NF2 NF2 ANKRD11 ANKRD11 HAND2 HAND2 SSUH2 SSUH2 BMP2 BMP2 MMP20 MMP20 MSX1 MSX1 PITX2 PITX2 PPARA PPARA ANKH ANKH WNT10A WNT10A GLI3 GLI3 INHBA INHBA FGF8 FGF8 TNFSF11 TNFSF11 AXIN2 AXIN2 BMP7 BMP7 SLC24A4 SLC24A4 OSR1 OSR1 DLX2 DLX2 DLX1 DLX1 LHX8 LHX8 CCDC154 CCDC154 ROGDI ROGDI LRP4 LRP4 TRAF6 TRAF6 PAX9 PAX9 BCOR BCOR AQP6 AQP6 SP7 SP7 AQP5 AQP5 AQP3 AQP3 DLX3 DLX3 NGFR NGFR JAG2 JAG2 AQP1 AQP1 ID3 ID3 FAM20C FAM20C PHEX PHEX BMPR1A BMPR1A RELT RELT TSPEAR TSPEAR SNX10 SNX10 TCIRG1 TCIRG1 FGF4 FGF4 HDAC1 HDAC1 RHOA RHOA PDGFRA PDGFRA OSR2 OSR2 SOSTDC1 SOSTDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STIM1Stromal interaction molecule 1 isoform X1. (791 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
LOC103002330LOW QUALITY PROTEIN: BCL-6 corepressor-like. (1668 aa)
FAM20ALOW QUALITY PROTEIN: pseudokinase FAM20A. (333 aa)
LAMA5LOW QUALITY PROTEIN: laminin subunit alpha-5. (3531 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1 isoform X1. (217 aa)
KLK4LOW QUALITY PROTEIN: kallikrein-4. (159 aa)
KLK5Kallikrein-5. (256 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
COL1A1LOW QUALITY PROTEIN: collagen alpha-1(I) chain. (1462 aa)
SRCTyrosine-protein kinase. (557 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
CTNNB1Catenin beta-1. (767 aa)
ENAMLOW QUALITY PROTEIN: enamelin. (1145 aa)
AMBNAmeloblastin. (421 aa)
ODAMLOW QUALITY PROTEIN: odontogenic ameloblast-associated protein. (287 aa)
RUNX2Runt-related transcription factor 2. (343 aa)
WDR72WD repeat-containing protein 72. (1104 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
FSTFollistatin isoform X1. (344 aa)
CNNM4Metal transporter CNNM4. (728 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
AMTNAmelotin. (249 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
NF2Merlin isoform X4. (619 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2593 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (130 aa)
SSUH2Protein SSUH2 homolog. (375 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
MMP20LOW QUALITY PROTEIN: matrix metalloproteinase-20. (484 aa)
MSX1Homeobox protein MSX-1. (229 aa)
PITX2Homeobox protein. (325 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
ANKHProgressive ankylosis protein homolog isoform X1. (492 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
INHBAInhibin beta A chain. (425 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (244 aa)
AXIN2Axin-2. (543 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
SLC24A4Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (616 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
DLX2Homeobox protein DLX-2. (251 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
LHX8LIM/homeobox protein Lhx8. (377 aa)
CCDC154Coiled-coil domain-containing protein 154. (698 aa)
ROGDIProtein rogdi homolog. (318 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1901 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
PAX9LOW QUALITY PROTEIN: paired box protein Pax-9. (341 aa)
BCORBCL-6 corepressor isoform X1. (1757 aa)
AQP6Aquaporin-6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (281 aa)
SP7Transcription factor Sp7. (431 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
AQP3Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
DLX3Homeobox protein DLX-3. (287 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (894 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
FAM20CExtracellular serine/threonine protein kinase FAM20C. (689 aa)
PHEXPhosphate-regulating neutral endopeptidase PHEX isoform X2. (749 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RELTTumor necrosis factor receptor superfamily member 19L isoform X1. (477 aa)
TSPEARThrombospondin-type laminin G domain and EAR repeat-containing protein. (665 aa)
SNX10Sorting nexin-10 isoform X1. (201 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (745 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
RHOATransforming protein RhoA. (193 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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