44 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1149 aa)
	GREM1	Gremlin. (184 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (992 aa)
	TMEM64	Transmembrane protein 64. (334 aa)
	PTCH1	LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
	NOG	Noggin. (154 aa)
	HOXA2	LOW QUALITY PROTEIN: homeobox protein Hox-A2. (369 aa)
	LRP5L	LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein. (469 aa)
	LRP5	Low-density lipoprotein receptor-related protein 5. (1080 aa)
	CHRD	Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (943 aa)
	NOTCH1	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B isoform X1. (1206 aa)
	TWSG1	Twisted gastrulation protein homolog 1 isoform X1. (223 aa)
	CDK6	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	OSTN	Osteocrin isoform X1. (138 aa)
	SEMA4D	semaphorin-4D; Belongs to the semaphorin family. (863 aa)
	HAND2	Heart- and neural crest derivatives-expressed protein 2. (130 aa)
	RANBP3L	Ran-binding protein 3-like isoform X1. (491 aa)
	CRIM1	Cysteine-rich motor neuron 1 protein isoform X2. (1037 aa)
	UCMA	Unique cartilage matrix-associated protein isoform X1. (138 aa)
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (453 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (247 aa)
	SOX9	Transcription factor SOX-9. (432 aa)
	AXIN2	Axin-2. (543 aa)
	TWIST2	Twist-related protein 2 isoform X1. (160 aa)
	RIOX1	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (578 aa)
	LOC103004151	LIM domain-containing protein 1-like. (279 aa)
	TNFAIP6	Tumor necrosis factor-inducible gene 6 protein. (277 aa)
	RORB	Nuclear receptor ROR-beta. (459 aa)
	SFRP1	Secreted frizzled-related protein 1. (295 aa)
	GDF10	Growth/differentiation factor 10. (544 aa)
	LOC103007666	Next to BRCA1 gene 1 protein isoform X1. (985 aa)
	LOC103005722	Next to BRCA1 gene 1 protein isoform X1. (985 aa)
	TOB1	Protein Tob1. (344 aa)
	ID3	DNA-binding protein inhibitor ID-3. (119 aa)
	MEN1	Menin. (517 aa)
	NOCT	Nocturnin. (362 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (231 aa)
	LIMD1	LIM domain-containing protein 1. (188 aa)
	SKI	Ski oncogene. (772 aa)
	SMAD6	Mothers against decapentaplegic homolog. (321 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	TNN	tenascin-N. (1266 aa)
	TWIST1	Twist-related protein 1. (153 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	LRP5	A0A384AFA5	A0A452C8I9	Axin-2.	Low-density lipoprotein receptor-related protein 5.	0.777
AXIN2	LRP5L	A0A384AFA5	A0A452C8S2	Axin-2.	LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein.	0.777
AXIN2	NOG	A0A384AFA5	A0A452CCN4	Axin-2.	Noggin.	0.507
AXIN2	SFRP1	A0A384AFA5	A0A384A4K5	Axin-2.	Secreted frizzled-related protein 1.	0.604
AXIN2	SOX9	A0A384AFA5	A0A384AFJ4	Axin-2.	Transcription factor SOX-9.	0.522
AXIN2	TWIST1	A0A384AFA5	A0A383YQH2	Axin-2.	Twist-related protein 1.	0.400
BAMBI	SMAD3	A0A384AME0	A0A383YTC5	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.594
BAMBI	SMAD6	A0A384AME0	A0A383YTH8	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.746
CDK6	NOTCH1	A0A384B982	A0A452C441	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1.	0.420
CHRD	NOG	A0A452C496	A0A452CCN4	Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.	Noggin.	0.778
CHRD	SMAD6	A0A452C496	A0A383YTH8	Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.	Mothers against decapentaplegic homolog.	0.532
CHRD	TNFAIP6	A0A452C496	A0A384A6Y6	Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.	Tumor necrosis factor-inducible gene 6 protein.	0.567
CHRD	TWSG1	A0A452C496	A0A384B9Q2	Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.	Twisted gastrulation protein homolog 1 isoform X1.	0.716
CRIM1	TWSG1	A0A384AW21	A0A384B9Q2	Cysteine-rich motor neuron 1 protein isoform X2.	Twisted gastrulation protein homolog 1 isoform X1.	0.440
HDAC4	SMAD3	A0A384AC10	A0A383YTC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Mothers against decapentaplegic homolog.	0.533
LIMD1	LOC103004151	A0A383Z1B9	A0A384A708	LIM domain-containing protein 1.	LIM domain-containing protein 1-like.	0.815
LOC103004151	LIMD1	A0A384A708	A0A383Z1B9	LIM domain-containing protein 1-like.	LIM domain-containing protein 1.	0.815
LOC103005722	LOC103007666	A0A383ZRP5	A0A383ZRQ5	Next to BRCA1 gene 1 protein isoform X1.	Next to BRCA1 gene 1 protein isoform X1.	0.989
LOC103007666	LOC103005722	A0A383ZRQ5	A0A383ZRP5	Next to BRCA1 gene 1 protein isoform X1.	Next to BRCA1 gene 1 protein isoform X1.	0.989
LRP5	AXIN2	A0A452C8I9	A0A384AFA5	Low-density lipoprotein receptor-related protein 5.	Axin-2.	0.777