STRINGSTRING
CTHRC1 CTHRC1 FGF2 FGF2 LRP5L LRP5L LRP5 LRP5 SCUBE3 SCUBE3 TP63 TP63 JUND JUND IL6ST IL6ST JAG1 JAG1 LRP3 LRP3 SUCO SUCO IGF1 IGF1 TENT5A TENT5A LTF LTF PDLIM7 PDLIM7 CTNNBIP1 CTNNBIP1 SMAD5 SMAD5 PPP3CA PPP3CA SCUBE2 SCUBE2 ILK ILK CCN1 CCN1 WDR63 WDR63 SOX11 SOX11 RUNX2 RUNX2 CTNNB1 CTNNB1 BMP4 BMP4 ZHX3 ZHX3 MEF2C MEF2C FERMT2 FERMT2 BMP2 BMP2 ACVR2B ACVR2B YAP1 YAP1 ATRAID ATRAID DDR2 DDR2 BMPR2 BMPR2 SFRP2 SFRP2 SMAD1 SMAD1 CCN4 CCN4 FBN2 FBN2 WWTR1 WWTR1 GLI3 GLI3 FFAR4 FFAR4 FBXO5 FBXO5 BMP7 BMP7 GDPD2 GDPD2 BMPR1B BMPR1B ACVR2A ACVR2A PRKD1 PRKD1 TMEM119 TMEM119 WNT10B WNT10B BMPR1A BMPR1A BMP6 BMP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LRP5LLOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein. (469 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1080 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3 isoform X1. (1004 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
JUNDTranscription factor jun-D. (262 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LRP3Low-density lipoprotein receptor-related protein 3. (645 aa)
SUCOSUN domain-containing ossification factor isoform X1. (1252 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
TENT5ATerminal nucleotidyltransferase 5A. (424 aa)
LTFLactotransferrin; Belongs to the transferrin family. (725 aa)
PDLIM7PDZ and LIM domain protein 7 isoform X1. (458 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (942 aa)
ILKIntegrin-linked protein kinase. (452 aa)
CCN1Protein CYR61. (382 aa)
WDR63WD repeat-containing protein 63 isoform X1. (892 aa)
SOX11Transcription factor SOX-11. (200 aa)
RUNX2Runt-related transcription factor 2. (343 aa)
CTNNB1Catenin beta-1. (767 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
ZHX3Zinc fingers and homeoboxes protein 3. (952 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
FERMT2Fermitin family homolog 2 isoform X1. (706 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
YAP1Transcriptional coactivator YAP1. (332 aa)
ATRAIDAll-trans retinoic acid-induced differentiation factor isoform X1. (271 aa)
DDR2Discoidin domain-containing receptor 2. (855 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CCN4WNT1-inducible-signaling pathway protein 1. (323 aa)
FBN2Fibrillin-2. (2784 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
FFAR4LOW QUALITY PROTEIN: free fatty acid receptor 4. (361 aa)
FBXO5F-box only protein 5. (448 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
GDPD2LOW QUALITY PROTEIN: glycerophosphoinositol inositolphosphodiesterase GDPD2. (539 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
TMEM119Transmembrane protein 119. (304 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP6Bone morphogenetic protein 6. (388 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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