STRINGSTRING
AGR2 AGR2 SYT17 SYT17 FN1 FN1 PLS1 PLS1 VIL1 VIL1 ERBB4 ERBB4 DBNL DBNL FGF8 FGF8 ZFYVE27 ZFYVE27 LIMK1 LIMK1 SMURF1 SMURF1 OCM2 OCM2 ZP3 ZP3 PRKN PRKN EZR EZR DLL1 DLL1 IL7 IL7 DSCAM DSCAM SYT2 SYT2 TBX20 TBX20 CELF1 CELF1 RAG2 RAG2 SASH3 SASH3 LOC103020229 LOC103020229 GLI1 GLI1 MTM1 MTM1 LOC103020607 LOC103020607 WNT3 WNT3 PROX1 PROX1 GHRHR GHRHR MUL1 MUL1 BMPR1A BMPR1A EDN1 EDN1 TRPV2 TRPV2 CAPN9 CAPN9 CDKL5 CDKL5 SHTN1 SHTN1 LPAR3 LPAR3 GPAM GPAM SYT4 SYT4 DRD2 DRD2 HLX HLX CRABP2 CRABP2 ACTN3 ACTN3 RASAL1 RASAL1 TBX5 TBX5 PEX5 PEX5 WNT3A WNT3A POU3F2 POU3F2 CSF1 CSF1 NGF NGF INSR INSR BBS2 BBS2 NTN1 NTN1 SOX15 SOX15 PPIB PPIB IGF1 IGF1 NOL12 NOL12 MKKS MKKS FGF9 FGF9 SPTBN4 SPTBN4 LOC103019784 LOC103019784 RIMS1 RIMS1 CDH4 CDH4 LOC114238097 LOC114238097 ARX ARX LOC102998237 LOC102998237 LOC103015198 LOC103015198 LEP LEP SMO SMO PLAA PLAA MYOD1 MYOD1 FGF2 FGF2 CHD7 CHD7 MEGF8 MEGF8 LOC103004507 LOC103004507 LOC114235950 LOC114235950 SRF SRF LOC103008148 LOC103008148 CREB1 CREB1 MAP3K13 MAP3K13 NOTCH1 NOTCH1 TBX2 TBX2 SYT3 SYT3 PIM1 PIM1 IST1 IST1 SEMA7A SEMA7A PPARD PPARD BBS4 BBS4 ISLR ISLR ISLR2 ISLR2 GATA6 GATA6 GHSR GHSR SMAD7 SMAD7 UNC13A UNC13A WNT2 WNT2 GPR21 GPR21 SYT1 SYT1 GHRH GHRH SEMA4D SEMA4D MEF2C MEF2C CPNE9 CPNE9 NIPBL NIPBL EFNA5 EFNA5 BCL2 BCL2 NEDD4L NEDD4L SLC6A3 SLC6A3 GOLGA4 GOLGA4 HEY2 HEY2 BMPR2 BMPR2 BMP10 BMP10 POU4F2 POU4F2 ZFPM2 ZFPM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGR2Anterior gradient protein 2 homolog. (175 aa)
SYT17Synaptotagmin-17. (474 aa)
FN1Fibronectin. (2376 aa)
PLS1Plastin-1. (630 aa)
VIL1Villin-1. (827 aa)
ERBB4Receptor protein-tyrosine kinase. (1298 aa)
DBNLDrebrin-like protein isoform X1. (448 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ZFYVE27Protrudin isoform X1. (414 aa)
LIMK1LOW QUALITY PROTEIN: LIM domain kinase 1. (636 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (719 aa)
OCM2Putative oncomodulin-2; Belongs to the parvalbumin family. (109 aa)
ZP3Zona pellucida sperm-binding protein 3. (421 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa)
EZREzrin. (586 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
IL7Interleukin-7 isoform X2. (178 aa)
DSCAMDown syndrome cell adhesion molecule. (2042 aa)
SYT2Synaptotagmin-2 isoform X1. (431 aa)
TBX20T-box transcription factor TBX20. (449 aa)
CELF1CUGBP Elav-like family member 1 isoform X1. (514 aa)
RAG2V(D)J recombination-activating protein 2. (527 aa)
SASH3SAM and SH3 domain-containing protein 3. (327 aa)
LOC103020229acetyl-CoA carboxylase 2 isoform X1. (2648 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
MTM1LOW QUALITY PROTEIN: myotubularin. (609 aa)
LOC103020607Signal transducer and activator of transcription. (794 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1 isoform X1. (370 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EDN1Endothelin-1. (202 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
CAPN9Calpain-9; Belongs to the peptidase C2 family. (526 aa)
CDKL5Cyclin-dependent kinase-like 5 isoform X1. (960 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (837 aa)
SYT4Synaptotagmin-4. (425 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
HLXH2.0-like homeobox protein. (442 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
ACTN3Alpha-actinin-3. (902 aa)
RASAL1rasGAP-activating-like protein 1 isoform X1. (813 aa)
TBX5T-box transcription factor TBX5 isoform X1. (536 aa)
PEX5Peroxisomal biogenesis factor 5 isoform X1. (640 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
POU3F2POU domain protein. (263 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
INSRTyrosine-protein kinase receptor. (1343 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
NTN1Netrin-1. (570 aa)
SOX15Protein SOX-15. (233 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
NOL12Nucleolar protein 12. (214 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2447 aa)
LOC103019784Regulating synaptic membrane exocytosis protein 1-like. (191 aa)
RIMS1Regulating synaptic membrane exocytosis protein 1 isoform X1. (1106 aa)
CDH4Cadherin-4; Cadherins are calcium-dependent cell adhesion proteins. (842 aa)
LOC114238097Intersectin-2-like. (356 aa)
ARXHomeobox protein ARX. (121 aa)
LOC102998237LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B-like. (745 aa)
LOC103015198LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B-like. (786 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
PLAAPhospholipase A-2-activating protein. (858 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (268 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2829 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2787 aa)
LOC103004507Copine-5. (290 aa)
LOC114235950Copine-5-like. (301 aa)
SRFSerum response factor. (464 aa)
LOC103008148Y-box-binding protein 3. (342 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (963 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
TBX2LOW QUALITY PROTEIN: T-box transcription factor TBX2. (592 aa)
SYT3LOW QUALITY PROTEIN: synaptotagmin-3. (508 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (401 aa)
IST1IST1 homolog isoform X1. (364 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (663 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
BBS4Bardet-Biedl syndrome 4 protein isoform X1. (517 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (428 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (747 aa)
GATA6Transcription factor GATA-6. (357 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
UNC13AProtein unc-13 homolog A isoform X1. (1730 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
GPR21Probable G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
GHRHSomatoliberin. (106 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (863 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
CPNE9Copine-9 isoform X2. (628 aa)
NIPBLNipped-B protein. (2803 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (213 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (993 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
GOLGA4Golgin subfamily A member 4 isoform X1. (2279 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
POU4F2POU domain protein. (408 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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