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SYT1 SYT1 MESD MESD APOE APOE APBB3 APBB3 ANKRA2 ANKRA2 LDLRAP1 LDLRAP1 SYT2 SYT2 PCSK9 PCSK9 HSP90B1 HSP90B1 PICALM PICALM LRPAP1 LRPAP1 CLTC CLTC APOB APOB APOA5 APOA5 LANCL1 LANCL1 AP2A1 AP2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYT1Synaptotagmin-1 isoform X1. (422 aa)
MESDLRP chaperone MESD. (232 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (313 aa)
APBB3Amyloid-beta A4 precursor protein-binding family B member 3 isoform X1. (515 aa)
ANKRA2Ankyrin repeat family A protein 2. (313 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (310 aa)
SYT2Synaptotagmin-2 isoform X1. (431 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (723 aa)
HSP90B1Endoplasmin. (805 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (713 aa)
LRPAP1Alpha-2-macroglobulin receptor-associated protein. (361 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
APOBApolipoprotein B-100. (4585 aa)
APOA5Apolipoprotein A-V isoform X1. (378 aa)
LANCL1Glutathione S-transferase LANCL1. (399 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (983 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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