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ATP11A ATP11A NKX2-5 NKX2-5 FZD7 FZD7 MSX1 MSX1 BMP2 BMP2 BCL2 BCL2 LMOD3 LMOD3 CAV3 CAV3 MEF2C MEF2C BMP4 BMP4 PTGDS PTGDS LOC103015737 LOC103015737 PLPP7 PLPP7 MYF5 MYF5 FRS2 FRS2 MYF6 MYF6 IGF1 IGF1 SMAD4 SMAD4 RBM24 RBM24 ARRB2 ARRB2 SHH SHH SHOX2 SHOX2 SIK1 SIK1 BHLHE41 BHLHE41 NOTCH1 NOTCH1 LOC103003275 LOC103003275 PI16 PI16 LOC102997198 LOC102997198 MYOCD MYOCD PROX1 PROX1 NLN NLN TRIM32 TRIM32 TMEM119 TMEM119 HDAC5 HDAC5 MMP14 MMP14 EZH2 EZH2 HDAC4 HDAC4 RBM38 RBM38 MYOG MYOG DLL1 DLL1 BHLHA15 BHLHA15 TRIM72 TRIM72 CCN3 CCN3 BMP10 BMP10 MSX2 MSX2 SMYD1 SMYD1 SOX6 SOX6 EDN1 EDN1 FBXO22 FBXO22 ACTN3 ACTN3 MTOR MTOR MAML1 MAML1 WNT3A WNT3A GSK3A GSK3A DMPK DMPK MAMSTR MAMSTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (987 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
MSX1Homeobox protein MSX-1. (229 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LMOD3Leiomodin-3. (575 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
PTGDSprostaglandin-H2 D-isomerase isoform X1; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
LOC103015737Mesoderm posterior protein 1. (126 aa)
PLPP7Inactive phospholipid phosphatase 7. (271 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
MYF6Myogenic factor 6. (242 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
RBM24RNA-binding protein 24. (200 aa)
ARRB2Beta-arrestin-2 isoform X1. (287 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (332 aa)
SIK1Serine/threonine-protein kinase SIK1. (836 aa)
BHLHE41Class E basic helix-loop-helix protein 41. (370 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
LOC103003275LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek5. (867 aa)
PI16Peptidase inhibitor 16 isoform X1; Belongs to the CRISP family. (463 aa)
LOC102997198Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
MYOCDMyocardin isoform X1. (985 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
NLNNeurolysin, mitochondrial isoform X1. (704 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
TMEM119Transmembrane protein 119. (304 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1138 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (746 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1149 aa)
RBM38RNA-binding protein 38. (158 aa)
MYOGMyogenin. (224 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (138 aa)
TRIM72Tripartite motif-containing protein 72. (457 aa)
CCN3CCN family member 3. (358 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MSX2Homeobox protein MSX-2. (268 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1 isoform X1. (490 aa)
SOX6Transcription factor SOX-6 isoform X1. (842 aa)
EDN1Endothelin-1. (202 aa)
FBXO22F-box only protein 22 isoform X1. (406 aa)
ACTN3Alpha-actinin-3. (902 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
MAML1Mastermind-like protein 1. (971 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (410 aa)
DMPKMyotonin-protein kinase isoform X1. (634 aa)
MAMSTRMEF2-activating motif and SAP domain-containing transcriptional regulator isoform X1. (430 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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