STRINGSTRING
FGF2 FGF2 PITX1 PITX1 FGF9 FGF9 SATB2 SATB2 HOXD3 HOXD3 IFT80 IFT80 LOC103016806 LOC103016806 PKD1 PKD1 EXT2 EXT2 HAND1 HAND1 WNT5B WNT5B COL1A1 COL1A1 NOG NOG SHOX2 SHOX2 ZMPSTE24 ZMPSTE24 OSR2 OSR2 MKKS MKKS BMP3 BMP3 CHST11 CHST11 EPYC EPYC TAPT1 TAPT1 BBS2 BBS2 SLC39A14 SLC39A14 HYAL1 HYAL1 HYAL3 HYAL3 HYAL2 HYAL2 IMPAD1 IMPAD1 PTH1R PTH1R WNT2B WNT2B FGF6 FGF6 MATN1 MATN1 BBS1 BBS1 FGF4 FGF4 HOXA3 HOXA3 HOXA11 HOXA11 HOXA5 HOXA5 MEF2D MEF2D ZBTB16 ZBTB16 SMAD5 SMAD5 PRRX1 PRRX1 SCUBE2 SCUBE2 CBS CBS CCN1 CCN1 CHRDL2 CHRDL2 RARB RARB EDN1 EDN1 BMPR1A BMPR1A MUSTN1 MUSTN1 CER1 CER1 NFIB NFIB CREB3L2 CREB3L2 RARA RARA ECM1 ECM1 THBS3 THBS3 PBXIP1 PBXIP1 LOC103010956 LOC103010956 CSGALNACT1 CSGALNACT1 WNT10B WNT10B RARG RARG COL2A1 COL2A1 HOXC4 HOXC4 HMGA2 HMGA2 TRPV4 TRPV4 CD44 CD44 OGN OGN SNX19 SNX19 DLX2 DLX2 OSR1 OSR1 BGN BGN MATN3 MATN3 RUNX1 RUNX1 ITGB8 ITGB8 BMPR1B BMPR1B SULF1 SULF1 SNAI1 SNAI1 SULF2 SULF2 AXIN2 AXIN2 SOX9 SOX9 MAPK3 MAPK3 RB1 RB1 COL11A2 COL11A2 CNMD CNMD GLI3 GLI3 IHH IHH ZEB1 ZEB1 ANXA6 ANXA6 CCN3 CCN3 EXT1 EXT1 SMAD1 SMAD1 SFRP2 SFRP2 SIX2 SIX2 ATF2 ATF2 BMPR2 BMPR2 CYTL1 CYTL1 CCN2 CCN2 MSX1 MSX1 MMP13 MMP13 BMP2 BMP2 OTOR OTOR ADAMTS12 ADAMTS12 HAND2 HAND2 HIF1A HIF1A MEF2C MEF2C BMP4 BMP4 GDF5 GDF5 CTNNB1 CTNNB1 SERPINH1 SERPINH1 RUNX2 RUNX2 IL17F IL17F PTGDS PTGDS MYF5 MYF5 DDRGK1 DDRGK1 COMP COMP COL3A1 COL3A1 TWSG1 TWSG1 MGP MGP GPLD1 GPLD1 MEX3C MEX3C SMPD3 SMPD3 TRIP11 TRIP11 ACAN ACAN ARID5A ARID5A SRF SRF TGFB1 TGFB1 LTBP3 LTBP3 FGF18 FGF18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
PITX1Homeobox protein. (199 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SATB2DNA-binding protein SATB. (853 aa)
HOXD3LOW QUALITY PROTEIN: homeobox protein Hox-D3. (431 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (808 aa)
LOC103016806LOW QUALITY PROTEIN: retinoic acid receptor beta-like. (358 aa)
PKD1LOW QUALITY PROTEIN: polycystin-1. (4200 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (770 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1 isoform X1. (217 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
COL1A1LOW QUALITY PROTEIN: collagen alpha-1(I) chain. (1462 aa)
NOGNoggin. (154 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (332 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
CHST11Carbohydrate sulfotransferase. (347 aa)
EPYCEpiphycan. (321 aa)
TAPT1Transmembrane anterior posterior transformation protein 1 homolog isoform X2. (462 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
SLC39A14Zinc transporter ZIP14 isoform X1. (490 aa)
HYAL1Hyaluronidase. (467 aa)
HYAL3Hyaluronidase. (517 aa)
HYAL2Hyaluronidase. (476 aa)
IMPAD1Inositol monophosphatase 3. (365 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (530 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MATN1Cartilage matrix protein. (495 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
HOXA3Homeobox protein Hox-A3 isoform X1. (341 aa)
HOXA11Homeobox protein Hox-A11. (314 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
MEF2DLOW QUALITY PROTEIN: myocyte-specific enhancer factor 2D. (512 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (942 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa)
CCN1Protein CYR61. (382 aa)
CHRDL2Chordin-like protein 2 isoform X1. (452 aa)
RARBRetinoic acid receptor beta. (584 aa)
EDN1Endothelin-1. (202 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MUSTN1Musculoskeletal embryonic nuclear protein 1. (82 aa)
CER1Cerberus. (273 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
ECM1Extracellular matrix protein 1 isoform X1. (543 aa)
THBS3LOW QUALITY PROTEIN: thrombospondin-3. (956 aa)
PBXIP1pre-B-cell leukemia transcription factor-interacting protein 1 isoform X1. (701 aa)
LOC103010956Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (361 aa)
CSGALNACT1Hexosyltransferase. (518 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
COL2A1Collagen alpha-1(II) chain. (1418 aa)
HOXC4Homeobox protein Hox-C4. (264 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
CD44CD44 antigen isoform X1. (769 aa)
OGNMimecan. (299 aa)
SNX19Sorting nexin-19 isoform X1. (1005 aa)
DLX2Homeobox protein DLX-2. (251 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
MATN3Matrilin-3. (483 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (457 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
SULF1Extracellular sulfatase Sulf-1 isoform X1. (1041 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
SULF2Extracellular sulfatase Sulf-2 isoform X1. (865 aa)
AXIN2Axin-2. (543 aa)
SOX9Transcription factor SOX-9. (432 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
RB1Retinoblastoma-associated protein. (816 aa)
COL11A2Collagen alpha-2(XI) chain isoform X2. (1736 aa)
CNMDLeukocyte cell-derived chemotaxin 1. (369 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
IHHIndian hedgehog protein. (309 aa)
ZEB1Zinc finger E-box-binding homeobox 1. (787 aa)
ANXA6Annexin. (673 aa)
CCN3CCN family member 3. (358 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CYTL1Cytokine-like protein 1. (135 aa)
CCN2Connective tissue growth factor. (268 aa)
MSX1Homeobox protein MSX-1. (229 aa)
MMP13Collagenase 3. (471 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
OTOROtoraplin. (129 aa)
ADAMTS12A disintegrin and metalloproteinase with thrombospondin motifs 12. (1549 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (130 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
GDF5Growth/differentiation factor 5. (511 aa)
CTNNB1Catenin beta-1. (767 aa)
SERPINH1Serpin H1; Belongs to the serpin family. (418 aa)
RUNX2Runt-related transcription factor 2. (343 aa)
IL17Finterleukin-17F. (204 aa)
PTGDSprostaglandin-H2 D-isomerase isoform X1; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
DDRGK1DDRGK domain-containing protein 1. (315 aa)
COMPCartilage oligomeric matrix protein. (658 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
TWSG1Twisted gastrulation protein homolog 1 isoform X1. (223 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (103 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (843 aa)
MEX3CRNA-binding E3 ubiquitin-protein ligase MEX3C. (530 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
TRIP11LOW QUALITY PROTEIN: thyroid receptor-interacting protein 11. (1980 aa)
ACANAggrecan core protein. (2090 aa)
ARID5AAT-rich interactive domain-containing protein 5A. (531 aa)
SRFSerum response factor. (464 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
LTBP3LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 3. (1209 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (20%) [HD]