STRINGSTRING
IGF1 IGF1 CUL3 CUL3 OOEP OOEP PIWIL2 PIWIL2 NPM2 NPM2 ZNF112 ZNF112 INSR INSR HOXA13 HOXA13 UBE2B UBE2B CDC23 CDC23 CDT1 CDT1 PRAP1 PRAP1 EDN1 EDN1 LOC103006469 LOC103006469 TGFA TGFA CDC27 CDC27 STRA8 STRA8 BTC BTC EREG EREG EPGN EPGN SIRT2 SIRT2 NUSAP1 NUSAP1 DMRT1 DMRT1 NUP62 NUP62 SPHK1 SPHK1 ANAPC11 ANAPC11 SH2B1 SH2B1 RB1 RB1 FGF8 FGF8 LOC102999029 LOC102999029 NSMCE2 NSMCE2 PDGFB PDGFB ANAPC5 ANAPC5 ANAPC7 ANAPC7 MSX2 MSX2 CD28 CD28 EGF EGF MSX1 MSX1 LOC103001360 LOC103001360 MAD2L1BP MAD2L1BP IL1B IL1B IL1A IL1A SMPD3 SMPD3 LOC103007245 LOC103007245 CDC16 CDC16 BHMG1 BHMG1 LOC103003530 LOC103003530 LRP5 LRP5 LOC103015712 LOC103015712 LRP5L LRP5L PRDM7 PRDM7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF1Insulin-like growth factor I isoform X1. (187 aa)
CUL3Cullin-3; Belongs to the cullin family. (746 aa)
OOEPOocyte-expressed protein homolog. (100 aa)
PIWIL2Piwi-like protein 2 isoform X1; Belongs to the argonaute family. (971 aa)
NPM2Nucleoplasmin-2. (178 aa)
ZNF112Zinc finger protein 112 isoform X1. (912 aa)
INSRTyrosine-protein kinase receptor. (1343 aa)
HOXA13Homeobox protein Hox-A13. (294 aa)
UBE2BUbiquitin-conjugating enzyme E2 B isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
CDT1DNA replication factor Cdt1. (530 aa)
PRAP1Proline-rich acidic protein 1. (150 aa)
EDN1Endothelin-1. (202 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
TGFAProtransforming growth factor alpha. (145 aa)
CDC27Cell division cycle protein 27 homolog isoform X1. (831 aa)
STRA8Stimulated by retinoic acid gene 8 protein homolog. (370 aa)
BTCProbetacellulin. (178 aa)
EREGProepiregulin isoform X1. (163 aa)
EPGNEpigen isoform X1. (153 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
NUSAP1Nucleolar and spindle-associated protein 1. (424 aa)
DMRT1Doublesex- and mab-3-related transcription factor 1 isoform X1. (347 aa)
NUP62Nuclear pore glycoprotein p62. (516 aa)
SPHK1Sphingosine kinase 1. (476 aa)
ANAPC11Anaphase-promoting complex subunit 11. (84 aa)
SH2B1SH2B adapter protein 1 isoform X1. (795 aa)
RB1Retinoblastoma-associated protein. (816 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC102999029Nuclear pore glycoprotein p62-like. (277 aa)
NSMCE2E3 SUMO-protein ligase NSE2. (246 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (596 aa)
MSX2Homeobox protein MSX-2. (268 aa)
CD28T-cell-specific surface glycoprotein CD28. (265 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1215 aa)
MSX1Homeobox protein MSX-1. (229 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
MAD2L1BPMAD2L1-binding protein. (273 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
LOC103007245LOW QUALITY PROTEIN: oocyte-expressed protein homolog. (140 aa)
CDC16Cell division cycle protein 16 homolog isoform X2. (536 aa)
BHMG1LOW QUALITY PROTEIN: basic helix-loop-helix and HMG box domain-containing protein 1. (635 aa)
LOC103003530LOW QUALITY PROTEIN: oocyte-expressed protein homolog. (147 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1080 aa)
LOC103015712Insulin-like. (117 aa)
LRP5LLOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein. (469 aa)
PRDM7Probable histone-lysine N-methyltransferase PRDM7. (961 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.