STRINGSTRING
TNNC1 TNNC1 TNNT2 TNNT2 TNNI1 TNNI1 MYL3 MYL3 RYR2 RYR2 PROX1 PROX1 PKP2 PKP2 PTCD2 PTCD2 BMPR1A BMPR1A MED1 MED1 DLL4 DLL4 HEG1 HEG1 LRP2 LRP2 FOXH1 FOXH1 POU4F1 POU4F1 MYL10 MYL10 ZFPM2 ZFPM2 EDNRA EDNRA MYL2 MYL2 BMP10 BMP10 NKX2-5 NKX2-5 HEY2 HEY2 ENG ENG ISL1 ISL1 TGFBR1 TGFBR1 SMAD4 SMAD4 SMAD7 SMAD7 NOTCH1 NOTCH1 CHD7 CHD7 TGFB1 TGFB1 DSP DSP NOG NOG HAND1 HAND1 MYBPC3 MYBPC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
TNNT2Troponin T, cardiac muscle isoform X1. (280 aa)
TNNI1Troponin I, slow skeletal muscle. (221 aa)
MYL3Myosin light chain 3. (199 aa)
RYR2Ryanodine receptor 2 isoform X1. (4884 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
PKP2Plakophilin-2 isoform X1. (826 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial isoform X1. (380 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1578 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
HEG1Protein HEG homolog 1. (1339 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4651 aa)
FOXH1Forkhead box protein H1. (360 aa)
POU4F1POU domain protein. (298 aa)
MYL10Myosin regulatory light chain 10. (167 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
ENGEndoglin isoform X1. (652 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2829 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
DSPDesmoplakin isoform X1. (2867 aa)
NOGNoggin. (154 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1 isoform X1. (217 aa)
MYBPC3Myosin-binding protein C, cardiac-type isoform X1. (1289 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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