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SLC4A2 SLC4A2 ATP12A ATP12A ATP6V0B ATP6V0B LOC103013659 LOC103013659 ATP1B2 ATP1B2 RNASEK RNASEK KCNMA1 KCNMA1 SLC8A1 SLC8A1 TMEM9 TMEM9 SLC12A3 SLC12A3 LRRK2 LRRK2 RAB38 RAB38 TMEM165 TMEM165 ATP1A1 ATP1A1 WNK1 WNK1 SLC12A1 SLC12A1 SLC9A1 SLC9A1 TCIRG1 TCIRG1 KCNQ1 KCNQ1 OTC OTC LOC103005600 LOC103005600 KCNJ10 KCNJ10 RHBG RHBG KLHL3 KLHL3 SLC9A4 SLC9A4 SLC9A2 SLC9A2 ATP1B1 ATP1B1 TMPRSS3 TMPRSS3 ATP6V1C1 ATP6V1C1 EDN1 EDN1 SLC9A6 SLC9A6 CUNHXorf21 CUNHXorf21 ATP6V1B1 ATP6V1B1 ATP6V0D2 ATP6V0D2 PDK2 PDK2 ATP6V0A4 ATP6V0A4 LOC103019480 LOC103019480 LOC103016593 LOC103016593 SNAPIN SNAPIN ATP6V1E1 ATP6V1E1 CLIC4 CLIC4 RHCE RHCE RAB7A RAB7A UBE3A UBE3A SLC4A8 SLC4A8 ATP5F1B ATP5F1B CA2 CA2 GRN GRN SLC4A1 SLC4A1 SLC12A6 SLC12A6 LOC103010682 LOC103010682 SLC26A3 SLC26A3 SLC26A4 SLC26A4 DMXL1 DMXL1 NOX1 NOX1 TMEM175 TMEM175 SLC9C1 SLC9C1 GPR89A GPR89A SLC12A8 SLC12A8 SCN7A SCN7A SLC9A7 SLC9A7 LOC103003700 LOC103003700 ATP6V0E2 ATP6V0E2 RAB39A RAB39A SLC12A5 SLC12A5 ATP6AP1 ATP6AP1 EDNRB EDNRB MAPK3 MAPK3 SLC12A9 SLC12A9 LACC1 LACC1 AQP11 AQP11 SLC11A1 SLC11A1 SLC4A3 SLC4A3 SLC9A9 SLC9A9 UMOD UMOD LOC102997552 LOC102997552 SLC12A2 SLC12A2 EXT1 EXT1 UPK3A UPK3A EDNRA EDNRA VPS33A VPS33A ATP6V0A2 ATP6V0A2 SLC4A7 SLC4A7 SLC9A3 SLC9A3 BCL2 BCL2 SLC1A3 SLC1A3 ATP6AP1L ATP6AP1L TM9SF4 TM9SF4 SLC4A4 SLC4A4 TFAP2B TFAP2B SLC4A9 SLC4A9 RHCG RHCG CFTR CFTR PDK4 PDK4 MAPK1 MAPK1 RAB20 RAB20 ATP4B ATP4B IL1A IL1A CLN6 CLN6 SLC12A4 SLC12A4 SCNN1B SCNN1B CA7 CA7 ATP6V0D1 ATP6V0D1 SCNN1G SCNN1G KCNH2 KCNH2 ATP1B3 ATP1B3 RHAG RHAG SLC9A5 SLC9A5 ATP1A3 ATP1A3 LOC103005321 LOC103005321 ATP4A ATP4A MLLT6 MLLT6 EXT2 EXT2 SLC4A10 SLC4A10 LOC103006898 LOC103006898 SLC9A8 SLC9A8 DMXL2 DMXL2 CLN3 CLN3 SLC4A5 SLC4A5 LOC103013954 LOC103013954 SLC12A7 SLC12A7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SLC4A2Anion exchange protein. (1259 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (929 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
LOC103013659V-type proton ATPase subunit B, brain isoform-like. (187 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
RNASEKRibonuclease kappa. (98 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X11. (1230 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (991 aa)
TMEM9Transmembrane protein 9 isoform X1. (289 aa)
SLC12A3Solute carrier family 12 member 3 isoform X1. (1049 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
RAB38Ras-related protein Rab-38. (211 aa)
TMEM165GDT1 family protein. (324 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
WNK1Serine/threonine-protein kinase WNK1. (2371 aa)
SLC12A1LOW QUALITY PROTEIN: solute carrier family 12 member 1. (1107 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (745 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
OTCOrnithine carbamoyltransferase, mitochondrial isoform X1; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
LOC103005600Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
RHBGAmmonium transporter Rh type B isoform X1; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (458 aa)
KLHL3Kelch-like protein 3. (601 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (771 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
TMPRSS3Transmembrane protease serine 3 isoform X1; Belongs to the peptidase S1 family. (476 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
EDN1Endothelin-1. (202 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (530 aa)
CUNHXorf21Uncharacterized protein CXorf21 homolog. (305 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (508 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (879 aa)
LOC103019480V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
LOC103016593V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (211 aa)
RHCEBlood group Rh(CE) polypeptide; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (417 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
SLC4A8Anion exchange protein. (1137 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (303 aa)
GRNGranulins. (587 aa)
SLC4A1Anion exchange protein. (856 aa)
SLC12A6Solute carrier family 12 member 6 isoform X1. (1150 aa)
LOC103010682Solute carrier family 12 member 3-like. (79 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (756 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
DMXL1dmX-like protein 1 isoform X1. (3084 aa)
NOX1LOW QUALITY PROTEIN: NADPH oxidase 1. (562 aa)
TMEM175Endosomal/lysosomal potassium channel TMEM175. (517 aa)
SLC9C1Sodium/hydrogen exchanger 10. (1187 aa)
GPR89AGolgi pH regulator A isoform X1. (455 aa)
SLC12A8Solute carrier family 12 member 8 isoform X1. (717 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1684 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (555 aa)
LOC103003700V-type proton ATPase subunit B, brain isoform-like. (345 aa)
ATP6V0E2V-type proton ATPase subunit e 2. (112 aa)
RAB39ARas-related protein Rab-39A. (217 aa)
SLC12A5Solute carrier family 12 member 5 isoform X1. (1143 aa)
ATP6AP1V-type proton ATPase subunit S1. (468 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
SLC12A9Solute carrier family 12 member 9. (920 aa)
LACC1Laccase domain-containing protein 1. (426 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
SLC11A1Natural resistance-associated macrophage protein 1 isoform X1. (547 aa)
SLC4A3Anion exchange protein. (1228 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (644 aa)
UMODUromodulin. (643 aa)
LOC102997552Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (439 aa)
SLC12A2Solute carrier family 12 member 2. (1143 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
UPK3AUroplakin-3a isoform X1. (287 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
VPS33AVacuolar protein sorting-associated protein 33A isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
SLC4A7Anion exchange protein. (1124 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (823 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
SLC1A3Amino acid transporter. (542 aa)
ATP6AP1LLOW QUALITY PROTEIN: V-type proton ATPase subunit S1-like protein. (343 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (642 aa)
SLC4A4Anion exchange protein. (1110 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (467 aa)
SLC4A9Anion exchange protein. (940 aa)
RHCGAmmonium transporter Rh type C; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (428 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
PDK4Protein-serine/threonine kinase. (407 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
RAB20Ras-related protein Rab-20 isoform X1. (231 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
CLN6Ceroid-lipofuscinosis neuronal protein 6. (473 aa)
SLC12A4Solute carrier family 12 member 4 isoform X1. (1055 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
CA7Carbonic anhydrase 7 isoform X1; Belongs to the alpha-carbonic anhydrase family. (264 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
KCNH2LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily H member 2. (813 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (266 aa)
RHAGAmmonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (433 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (830 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
LOC103005321Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1014 aa)
MLLT6Protein AF-17. (1133 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (770 aa)
SLC4A10Anion exchange protein. (1178 aa)
LOC103006898LOW QUALITY PROTEIN: ATP synthase subunit beta, mitochondrial-like. (213 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (602 aa)
DMXL2LOW QUALITY PROTEIN: dmX-like protein 2. (3062 aa)
CLN3Battenin. (446 aa)
SLC4A5Anion exchange protein. (1146 aa)
LOC103013954Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (278 aa)
SLC12A7Solute carrier family 12 member 7. (978 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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