STRINGSTRING
CTNNB1 CTNNB1 FRS2 FRS2 SOX5 SOX5 WNT2 WNT2 ORC3 ORC3 ELL3 ELL3 DCT DCT MELK MELK RAPGEF1 RAPGEF1 TEAD3 TEAD3 DBN1 DBN1 NUMBL NUMBL ZNF503 ZNF503 NF1 NF1 SHANK3 SHANK3 IFT20 IFT20 RORA RORA ARX ARX RPGRIP1 RPGRIP1 SHH SHH ZZEF1 ZZEF1 SMO SMO VAX1 VAX1 DIXDC1 DIXDC1 AKNA AKNA FGF2 FGF2 LNX2 LNX2 DOCK7 DOCK7 DMRTA2 DMRTA2 ASCL1 ASCL1 BTG2 BTG2 KIF14 KIF14 ADGRG1 ADGRG1 ZNF423 ZNF423 POU3F2 POU3F2 WNT3A WNT3A RERE RERE KCNA1 KCNA1 EPHB1 EPHB1 BBS1 BBS1 LHX5 LHX5 NDUFS2 NDUFS2 ARHGEF2 ARHGEF2 DRD2 DRD2 CTNNA1 CTNNA1 KIFAP3 KIFAP3 ILK ILK EMX2 EMX2 FZD6 FZD6 PCM1 PCM1 DAGLA DAGLA PROX1 PROX1 OTP OTP IGF2BP1 IGF2BP1 PAFAH1B1 PAFAH1B1 EML1 EML1 HOOK3 HOOK3 WNT1 WNT1 RACGAP1 RACGAP1 TARBP2 TARBP2 NEUROD4 NEUROD4 FOXG1 FOXG1 PAX6 PAX6 POU3F1 POU3F1 LIMS2 LIMS2 CDON CDON NUMB NUMB GBX2 GBX2 ATF5 ATF5 DAGLB DAGLB FZD9 FZD9 FGF8 FGF8 GLI3 GLI3 NDE1 NDE1 CEP120 CEP120 ACSL6 ACSL6 POU3F4 POU3F4 SOX10 SOX10 PLXNB2 PLXNB2 HHIP HHIP ITGB1 ITGB1 EGF EGF NR2E1 NR2E1 HIF1A HIF1A FZD3 FZD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNB1Catenin beta-1. (767 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
SOX5Transcription factor SOX-5 isoform X1. (729 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ORC3Origin recognition complex subunit 3 isoform X1. (714 aa)
ELL3RNA polymerase II elongation factor ELL3. (400 aa)
DCTL-dopachrome tautomerase isoform X1. (554 aa)
MELKNon-specific serine/threonine protein kinase. (665 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1238 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (497 aa)
DBN1Drebrin isoform X1. (644 aa)
NUMBLNumb-like protein. (560 aa)
ZNF503Zinc finger protein 503. (648 aa)
NF1Neurofibromin. (2821 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3. (1465 aa)
IFT20LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog. (159 aa)
RORANuclear receptor ROR-alpha. (386 aa)
ARXHomeobox protein ARX. (121 aa)
RPGRIP1LOW QUALITY PROTEIN: X-linked retinitis pigmentosa GTPase regulator-interacting protein 1. (1219 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
ZZEF1LOW QUALITY PROTEIN: zinc finger ZZ-type and EF-hand domain-containing protein 1. (2945 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
VAX1Ventral anterior homeobox 1. (350 aa)
DIXDC1Dixin isoform X1. (706 aa)
AKNAAT-hook-containing transcription factor isoform X1. (1433 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LNX2Ligand of Numb protein X 2. (681 aa)
DOCK7Dedicator of cytokinesis protein 7 isoform X1; Belongs to the DOCK family. (2023 aa)
DMRTA2Doublesex- and mab-3-related transcription factor A2. (390 aa)
ASCL1Achaete-scute homolog 1. (169 aa)
BTG2Protein BTG2. (162 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1640 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (686 aa)
ZNF423Zinc finger protein 423. (1224 aa)
POU3F2POU domain protein. (263 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
REREArginine-glutamic acid dipeptide repeats protein. (1289 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
LHX5LIM/homeobox protein Lhx5. (404 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1; Belongs to the complex I 49 kDa subunit family. (462 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2 isoform X1. (1179 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CTNNA1Catenin alpha-1. (906 aa)
KIFAP3Kinesin-associated protein 3 isoform X1. (793 aa)
ILKIntegrin-linked protein kinase. (452 aa)
EMX2Homeobox protein EMX2 isoform X1. (253 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
PCM1Pericentriolar material 1 protein isoform X1. (2123 aa)
DAGLALOW QUALITY PROTEIN: sn1-specific diacylglycerol lipase alpha. (1037 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
OTPLOW QUALITY PROTEIN: homeobox protein orthopedia. (324 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
EML1Echinoderm microtubule-associated protein-like 1 isoform X1. (852 aa)
HOOK3Protein Hook homolog 3 isoform X1. (680 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
FOXG1Forkhead box protein G1. (352 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
POU3F1POU domain, class 3, transcription factor 1. (128 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein 2. (453 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1251 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
GBX2Homeobox protein GBX-2. (253 aa)
ATF5Cyclic AMP-dependent transcription factor ATF-5. (176 aa)
DAGLBSn1-specific diacylglycerol lipase beta isoform X1. (669 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (408 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
NDE1Nuclear distribution protein nudE homolog 1 isoform X1. (346 aa)
CEP120Centrosomal protein of 120 kDa isoform X1. (987 aa)
ACSL6long-chain-fatty-acid--CoA ligase 6 isoform X1. (746 aa)
POU3F4POU domain protein. (363 aa)
SOX10Transcription factor SOX-10. (468 aa)
PLXNB2plexin-B2. (1808 aa)
HHIPHedgehog-interacting protein isoform X1. (700 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1215 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (400 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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