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LOC103006469 LOC103006469 RNF43 RNF43 WNT11 WNT11 CTNNB1 CTNNB1 LOC103001360 LOC103001360 TRIM71 TRIM71 NR2E1 NR2E1 SIX2 SIX2 SFRP2 SFRP2 CEP120 CEP120 GLI3 GLI3 XRCC5 XRCC5 FGF8 FGF8 SOX9 SOX9 AXIN2 AXIN2 SART3 SART3 TBX3 TBX3 RARG RARG WNT1 WNT1 WNT10B WNT10B GBA GBA NFIB NFIB SCRG1 SCRG1 NF1 NF1 CTC1 CTC1 IFT20 IFT20 LOC103016806 LOC103016806 SHH SHH PTCH1 PTCH1 SHOX2 SHOX2 FGF2 FGF2 TGFB1 TGFB1 TP63 TP63 BRCA2 BRCA2 BYSL BYSL LIG4 LIG4 SHB SHB IRS2 IRS2 ELL3 ELL3 ETV6 ETV6 LOC103011148 LOC103011148 FGF10 FGF10 BABAM1 BABAM1 RUNX2 RUNX2 HOXB4 HOXB4 IRF6 IRF6 FGF9 FGF9 CDKN2C CDKN2C OSR2 OSR2 CD109 CD109 ERCC2 ERCC2 KDR KDR ARIH2 ARIH2 WNT2B WNT2B KDF1 KDF1 SFN SFN YTHDF2 YTHDF2 FGF4 FGF4 HOXA3 HOXA3 NES NES PRRX1 PRRX1 HMX2 HMX2 RARB RARB WNT3 WNT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
RNF43E3 ubiquitin-protein ligase RNF43. (783 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CTNNB1Catenin beta-1. (767 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (641 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (400 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
CEP120Centrosomal protein of 120 kDa isoform X1. (987 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
XRCC5X-ray repair cross-complementing protein 5 isoform X1. (733 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SOX9Transcription factor SOX-9. (432 aa)
AXIN2Axin-2. (543 aa)
SART3Squamous cell carcinoma antigen recognized by T-cells 3 isoform X1. (978 aa)
TBX3T-box transcription factor TBX3. (670 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
GBAGlucosylceramidase. (536 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
SCRG1Scrapie-responsive protein 1. (98 aa)
NF1Neurofibromin. (2821 aa)
CTC1CST complex subunit CTC1. (1202 aa)
IFT20LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog. (159 aa)
LOC103016806LOW QUALITY PROTEIN: retinoic acid receptor beta-like. (358 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
PTCH1LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (332 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
BRCA2LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (3340 aa)
BYSLBystin. (433 aa)
LIG4DNA ligase. (911 aa)
SHBLOW QUALITY PROTEIN: SH2 domain-containing adapter protein B. (509 aa)
IRS2Insulin receptor substrate 2. (507 aa)
ELL3RNA polymerase II elongation factor ELL3. (400 aa)
ETV6Transcription factor ETV6 isoform X1. (452 aa)
LOC103011148Breast cancer type 2 susceptibility protein-like. (273 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
BABAM1BRISC and BRCA1-A complex member 1. (330 aa)
RUNX2Runt-related transcription factor 2. (343 aa)
HOXB4Homeobox protein Hox-B4. (251 aa)
IRF6Interferon regulatory factor 6 isoform X1. (472 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
CD109CD109 antigen. (1312 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD. (760 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ARIH2RBR-type E3 ubiquitin transferase. (491 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
KDF1LOW QUALITY PROTEIN: keratinocyte differentiation factor 1. (397 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
YTHDF2YTH domain-containing family protein 2. (546 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
HOXA3Homeobox protein Hox-A3 isoform X1. (341 aa)
NESNestin; Belongs to the intermediate filament family. (1537 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
HMX2Homeobox protein HMX2. (274 aa)
RARBRetinoic acid receptor beta. (584 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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