STRINGSTRING
SMAD6 SMAD6 TAF3 TAF3 NKX3-1 NKX3-1 NR0B2 NR0B2 PURA PURA ID3 ID3 DDIT3 DDIT3 DAXX DAXX LYAR LYAR ID1 ID1 SMAD7 SMAD7 SIN3A SIN3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD6Mothers against decapentaplegic homolog. (321 aa)
TAF3Transcription initiation factor TFIID subunit 3. (926 aa)
NKX3-1Homeobox protein Nkx-3.1. (153 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (260 aa)
PURATranscriptional activator protein Pur-alpha. (260 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
DAXXDeath domain-associated protein 6. (755 aa)
LYARCell growth-regulating nucleolar protein. (378 aa)
ID1DNA-binding protein inhibitor ID-1. (87 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SIN3APaired amphipathic helix protein Sin3a. (1274 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.