STRINGSTRING
CASQ2 CASQ2 SLC9A1 SLC9A1 RYR2 RYR2 CABP4 CABP4 CACNB1 CACNB1 LOC103018596 LOC103018596 PKD2 PKD2 CABP2 CABP2 LOC114238926 LOC114238926 LOC114238950 LOC114238950 LOC103011591 LOC103011591 LOC114238951 LOC114238951 STIM2 STIM2 MRLN MRLN PDE4B PDE4B GEM GEM LOC103011186 LOC103011186 CABP5 CABP5 HRC HRC CRACR2A CRACR2A STAC STAC CAV3 CAV3 REM1 REM1 JPH2 JPH2 SRI SRI CUNH1orf226 CUNH1orf226 CASQ1 CASQ1 DRD2 DRD2 LOC103013686 LOC103013686 CUNH4orf3 CUNH4orf3 LOC103007734 LOC103007734 ATP1B1 ATP1B1 JPH3 JPH3 STIM1 STIM1 STIMATE STIMATE LOC103018378 LOC103018378 JSRP1 JSRP1 CBARP CBARP UBQLN1 UBQLN1 STAC2 STAC2 LOC103006874 LOC103006874 STAC3 STAC3 R3HDM2 R3HDM2 CACNB3 CACNB3 REM2 REM2 DRD3 DRD3 HPCA HPCA PLCG2 PLCG2 CACNB4 CACNB4 FKBP1B FKBP1B CABP1 CABP1 HSPA2 HSPA2 CLIC2 CLIC2 SMIM6 SMIM6 ATP2A1 ATP2A1 CALM2 CALM2 VMP1 VMP1 PLN PLN GNB5 GNB5 CACNB2 CACNB2 RAB44 RAB44 RRAD RRAD SELENON SELENON R3HDM1 R3HDM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
RYR2Ryanodine receptor 2 isoform X1. (4884 aa)
CABP4Calcium-binding protein 4. (272 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform X4. (617 aa)
LOC103018596Calmodulin-like; Belongs to the calmodulin family. (149 aa)
PKD2Polycystin-2. (763 aa)
CABP2Calcium-binding protein 2 isoform X1. (226 aa)
LOC114238926Triadin-like. (164 aa)
LOC114238950Triadin-like. (103 aa)
LOC103011591Triadin. (176 aa)
LOC114238951Triadin-like. (283 aa)
STIM2Stromal interaction molecule 2. (726 aa)
MRLNMyoregulin isoform X1. (79 aa)
PDE4BPhosphodiesterase. (736 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
LOC103011186Myosin light chain 6B-like; Belongs to the calmodulin family. (366 aa)
CABP5Calcium-binding protein 5 isoform X1. (173 aa)
HRCSarcoplasmic reticulum histidine-rich calcium-binding protein isoform X1. (649 aa)
CRACR2AEF-hand calcium-binding domain-containing protein 4B isoform X1. (723 aa)
STACSH3 and cysteine-rich domain-containing protein isoform X1. (402 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (314 aa)
JPH2Junctophilin-2. (474 aa)
SRISorcin. (199 aa)
CUNH1orf226Uncharacterized protein C1orf226 homolog isoform X1. (689 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (397 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC103013686Huntingtin isoform X1. (2391 aa)
CUNH4orf3Uncharacterized protein C4orf3 homolog. (68 aa)
LOC103007734Huntingtin-like. (660 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (741 aa)
STIM1Stromal interaction molecule 1 isoform X1. (791 aa)
STIMATEStore-operated calcium entry regulator STIMATE isoform X1. (294 aa)
LOC103018378Uncharacterized protein C4orf3-like. (68 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1 isoform X1. (329 aa)
CBARPVoltage-dependent calcium channel beta subunit-associated regulatory protein. (393 aa)
UBQLN1Ubiquilin-1 isoform X1. (590 aa)
STAC2SH3 and cysteine-rich domain-containing protein 2 isoform X1. (409 aa)
LOC103006874Huntingtin-associated protein 1-like. (636 aa)
STAC3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (360 aa)
R3HDM2R3H domain-containing protein 2 isoform X1. (1092 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3. (539 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
HPCANeuron-specific calcium-binding protein hippocalcin isoform X1. (220 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (502 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
CABP1Calcium-binding protein 1 isoform X1. (280 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa)
CLIC2LOW QUALITY PROTEIN: chloride intracellular channel protein 2. (248 aa)
SMIM6Small integral membrane protein 6. (59 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
VMP1Vacuole membrane protein 1. (377 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (301 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa)
RAB44Ras-related protein Rab-44. (981 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
SELENONSelenoprotein N. (524 aa)
R3HDM1LOW QUALITY PROTEIN: R3H domain-containing protein 1. (1097 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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