STRINGSTRING
RMI2 RMI2 RPA3 RPA3 YBX1 YBX1 DARS2 DARS2 MCM5 MCM5 DIS3L DIS3L YBX2 YBX2 EIF5A EIF5A CCAR1 CCAR1 LIG1 LIG1 RPS11 RPS11 MCM4 MCM4 RPS28 RPS28 CSDE1 CSDE1 RPA2 RPA2 ZCCHC17 ZCCHC17 EIF1AD EIF1AD NABP1 NABP1 LOC103013956 LOC103013956 MNDA MNDA EIF1AX EIF1AX POLR2G POLR2G PSMC5 PSMC5 SSBP1 SSBP1 POT1 POT1 PSMC2 PSMC2 RPA1 RPA1 RADX RADX LIN28A LIN28A MCM2 MCM2 NABP2 NABP2 PSMC4 PSMC4 MRPS12 MRPS12 DHX8 DHX8 RPA4 RPA4 PSMC1 PSMC1 PSMC3 PSMC3 MEIOB MEIOB YARS YARS KARS KARS SUPT6H SUPT6H EIF2S1 EIF2S1 DIS3L2 DIS3L2 RPL8 RPL8 TEN1 TEN1 DIS3 DIS3 LOC103003043 LOC103003043 MCM7 MCM7 STN1 STN1 PDCD11 PDCD11 EXOSC1 EXOSC1 NARS2 NARS2 DDIAS DDIAS CARHSP1 CARHSP1 POLR3H POLR3H CSDC2 CSDC2 MCM10 MCM10 PNPT1 PNPT1 SRBD1 SRBD1 LIG3 LIG3 MCM9 MCM9 LIN28B LIN28B AIMP1 AIMP1 MCM8 MCM8 NARS NARS MCM6 MCM6 DARS DARS PSMC6 PSMC6 RPS23 RPS23 EXOSC2 EXOSC2 SPOUT1 SPOUT1 POLR2H POLR2H TTC14 TTC14 RNGTT RNGTT EXOSC3 EXOSC3 LIG4 LIG4 EIF5A2 EIF5A2 MRPL2 MRPL2 BRCA2 BRCA2 MCM3 MCM3 LOC103014355 LOC103014355 LOC103008148 LOC103008148 LOC103015078 LOC103015078 AIM2 AIM2 LOC103008473 LOC103008473 LOC102999486 LOC102999486
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RMI2LOW QUALITY PROTEIN: recQ-mediated genome instability protein 2. (175 aa)
RPA3Replication protein A 14 kDa subunit isoform X1. (121 aa)
YBX1Nuclease-sensitive element-binding protein 1. (356 aa)
DARS2aspartate--tRNA ligase, mitochondrial isoform X1. (652 aa)
MCM5DNA helicase; Belongs to the MCM family. (721 aa)
DIS3LDIS3-like exonuclease 1 isoform X1; Belongs to the RNR ribonuclease family. (1048 aa)
YBX2Y-box-binding protein 2. (287 aa)
EIF5AEukaryotic translation initiation factor 5A. (154 aa)
CCAR1Cell division cycle and apoptosis regulator protein 1. (1150 aa)
LIG1DNA ligase. (918 aa)
RPS1140S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
MCM4DNA helicase; Belongs to the MCM family. (739 aa)
RPS2840S ribosomal protein S28. (69 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (844 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
ZCCHC17Nucleolar protein of 40 kDa. (241 aa)
EIF1ADProbable RNA-binding protein EIF1AD. (165 aa)
NABP1SOSS complex subunit B2 isoform X1. (205 aa)
LOC103013956Gamma-interferon-inducible protein 16-like isoform X1. (532 aa)
MNDALOW QUALITY PROTEIN: myeloid cell nuclear differentiation antigen. (338 aa)
EIF1AXEukaryotic translation initiation factor 1A, X-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
SSBP1Single-stranded DNA-binding protein, mitochondrial. (148 aa)
POT1Protection of telomeres protein 1 isoform X1. (785 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
RADXRPA-related protein RADX. (847 aa)
LIN28AProtein lin-28 homolog A. (205 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
NABP2SOSS complex subunit B1. (211 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
MRPS1228S ribosomal protein S12, mitochondrial; Belongs to the universal ribosomal protein uS12 family. (139 aa)
DHX8ATP-dependent RNA helicase DHX8. (1214 aa)
RPA4Replication protein A 30 kDa subunit. (259 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMC326S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X1. (471 aa)
YARSTyrosine--tRNA ligase. (528 aa)
KARSLysine--tRNA ligase. (624 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (882 aa)
RPL860S ribosomal protein L8. (226 aa)
TEN1CST complex subunit TEN1. (123 aa)
DIS3Exosome complex exonuclease RRP44 isoform X1; Belongs to the RNR ribonuclease family. (958 aa)
LOC103003043Nuclease-sensitive element-binding protein 1. (331 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (369 aa)
PDCD11Protein RRP5 homolog isoform X1. (1875 aa)
EXOSC1Exosome complex component CSL4 isoform X1. (195 aa)
NARS2Probable asparagine--tRNA ligase, mitochondrial isoform X1. (477 aa)
DDIASDNA damage-induced apoptosis suppressor protein. (997 aa)
CARHSP1Calcium-regulated heat-stable protein 1. (147 aa)
POLR3HDNA-directed RNA polymerase III subunit RPC8. (204 aa)
CSDC2Cold shock domain-containing protein C2. (250 aa)
MCM10Protein MCM10 homolog. (873 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (776 aa)
SRBD1S1 RNA-binding domain-containing protein 1. (995 aa)
LIG3DNA ligase. (1031 aa)
MCM9LOW QUALITY PROTEIN: DNA helicase MCM9; Belongs to the MCM family. (1146 aa)
LIN28BProtein lin-28 homolog B isoform X1. (270 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (313 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (837 aa)
NARSasparagine--tRNA ligase, cytoplasmic isoform X1. (559 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
DARSaspartate--tRNA ligase, cytoplasmic isoform X1. (501 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
RPS2340S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
EXOSC2Exosome complex component RRP4 isoform X1. (293 aa)
SPOUT1Putative methyltransferase C9orf114 homolog isoform X1. (376 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
TTC14Tetratricopeptide repeat protein 14 isoform X1. (772 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (610 aa)
EXOSC3Exosome complex component RRP40 isoform X1. (275 aa)
LIG4DNA ligase. (911 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
MRPL239S ribosomal protein L2, mitochondrial isoform X1. (306 aa)
BRCA2LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (3340 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
LOC103014355Single-stranded DNA-binding protein, mitochondrial. (148 aa)
LOC103008148Y-box-binding protein 3. (342 aa)
LOC103015078LOW QUALITY PROTEIN: protein lin-28 homolog A-like. (205 aa)
AIM2LOW QUALITY PROTEIN: interferon-inducible protein AIM2. (230 aa)
LOC103008473Eukaryotic translation initiation factor 1A, X-chromosomal-like isoform X1. (149 aa)
LOC102999486CST complex subunit TEN1-like. (123 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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