(10 nodes) Lipase, LIPH-type network (Balaenoptera acutorostrata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LIPH	Lipase member H. (441 aa)
	LIPI	Lipase member I. (460 aa)
	LIPC	Hepatic triacylglycerol lipase. (500 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
	PNLIPRP1	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
	PNLIP	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
	PNLIPRP3	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (562 aa)
	PLA1A	Phospholipase A1 member A isoform X1. (456 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
	LIPG	Endothelial lipase. (500 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LIPC	LIPG	A0A383YSZ3	A0A384BCU0	Hepatic triacylglycerol lipase.	Endothelial lipase.	0.900
LIPC	LPL	A0A383YSZ3	A0A384AAG0	Hepatic triacylglycerol lipase.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.923
LIPC	PNLIP	A0A383YSZ3	A0A383ZDS7	Hepatic triacylglycerol lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.915
LIPC	PNLIPRP1	A0A383YSZ3	A0A383ZDR1	Hepatic triacylglycerol lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.908
LIPC	PNLIPRP2	A0A383YSZ3	A0A383ZDG3	Hepatic triacylglycerol lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.903
LIPC	PNLIPRP3	A0A383YSZ3	A0A383ZDZ5	Hepatic triacylglycerol lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.905
LIPG	LIPC	A0A384BCU0	A0A383YSZ3	Endothelial lipase.	Hepatic triacylglycerol lipase.	0.900
LIPG	LPL	A0A384BCU0	A0A384AAG0	Endothelial lipase.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.901
LIPG	PNLIP	A0A384BCU0	A0A383ZDS7	Endothelial lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.904
LIPG	PNLIPRP1	A0A384BCU0	A0A383ZDR1	Endothelial lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.907
LIPG	PNLIPRP2	A0A384BCU0	A0A383ZDG3	Endothelial lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.902
LIPG	PNLIPRP3	A0A384BCU0	A0A383ZDZ5	Endothelial lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.906
LPL	LIPC	A0A384AAG0	A0A383YSZ3	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Hepatic triacylglycerol lipase.	0.923
LPL	LIPG	A0A384AAG0	A0A384BCU0	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Endothelial lipase.	0.901
LPL	PNLIP	A0A384AAG0	A0A383ZDS7	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.905
LPL	PNLIPRP1	A0A384AAG0	A0A383ZDR1	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.909
LPL	PNLIPRP2	A0A384AAG0	A0A383ZDG3	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.903
LPL	PNLIPRP3	A0A384AAG0	A0A383ZDZ5	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.906
PNLIP	LIPC	A0A383ZDS7	A0A383YSZ3	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Hepatic triacylglycerol lipase.	0.915
PNLIP	LIPG	A0A383ZDS7	A0A384BCU0	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Endothelial lipase.	0.904