(27 nodes) Sm domain network (Balaenoptera acutorostrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SNRPD2	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
	LSM14A	Protein LSM14 homolog A isoform X1. (502 aa)
	LSM11	LOW QUALITY PROTEIN: U7 snRNA-associated Sm-like protein LSm11. (359 aa)
	SNRPF	Small nuclear ribonucleoprotein F. (86 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
	NAA38	N-alpha-acetyltransferase 38, NatC auxiliary subunit isoform X1. (173 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	LSM2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	LSM6	U6 snRNA-associated Sm-like protein LSm6. (80 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	LSM10	U7 snRNA-associated Sm-like protein LSm10. (123 aa)
	LSM12	Protein LSM12 homolog. (195 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
	LSM7	U6 snRNA-associated Sm-like protein LSm7. (135 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	GEMIN7	Gem-associated protein 7. (128 aa)
	GEMIN6	Gem-associated protein 6. (166 aa)
	ATXN2	Ataxin-2 isoform X1. (1049 aa)
	ATXN2L	Ataxin-2-like protein isoform X1. (989 aa)
	LOC114236421	Small nuclear ribonucleoprotein G-like. (68 aa)
	EDC3	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3. (506 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN2	ATXN2L	A0A452CMH1	A0A452CK69	Ataxin-2 isoform X1.	Ataxin-2-like protein isoform X1.	0.915
ATXN2	LSM12	A0A452CMH1	A0A383ZZC1	Ataxin-2 isoform X1.	Protein LSM12 homolog.	0.875
ATXN2	NAA38	A0A452CMH1	A0A383YUA4	Ataxin-2 isoform X1.	N-alpha-acetyltransferase 38, NatC auxiliary subunit isoform X1.	0.503
ATXN2	SNRPB	A0A452CMH1	A0A384B9C2	Ataxin-2 isoform X1.	Small nuclear ribonucleoprotein-associated protein.	0.503
ATXN2	SNRPN	A0A452CMH1	A0A383ZVU2	Ataxin-2 isoform X1.	Small nuclear ribonucleoprotein-associated protein.	0.753
ATXN2L	ATXN2	A0A452CK69	A0A452CMH1	Ataxin-2-like protein isoform X1.	Ataxin-2 isoform X1.	0.915
ATXN2L	EDC3	A0A452CK69	A0A452C6G2	Ataxin-2-like protein isoform X1.	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	0.409
ATXN2L	LSM12	A0A452CK69	A0A383ZZC1	Ataxin-2-like protein isoform X1.	Protein LSM12 homolog.	0.829
ATXN2L	LSM14A	A0A452CK69	A0A383YQJ1	Ataxin-2-like protein isoform X1.	Protein LSM14 homolog A isoform X1.	0.546
ATXN2L	NAA38	A0A452CK69	A0A383YUA4	Ataxin-2-like protein isoform X1.	N-alpha-acetyltransferase 38, NatC auxiliary subunit isoform X1.	0.503
ATXN2L	SNRPB	A0A452CK69	A0A384B9C2	Ataxin-2-like protein isoform X1.	Small nuclear ribonucleoprotein-associated protein.	0.503
ATXN2L	SNRPN	A0A452CK69	A0A383ZVU2	Ataxin-2-like protein isoform X1.	Small nuclear ribonucleoprotein-associated protein.	0.753
EDC3	ATXN2L	A0A452C6G2	A0A452CK69	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	Ataxin-2-like protein isoform X1.	0.409
EDC3	LSM1	A0A452C6G2	A0A383ZTQ4	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.	0.841
EDC3	LSM14A	A0A452C6G2	A0A383YQJ1	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	Protein LSM14 homolog A isoform X1.	0.803
EDC3	LSM2	A0A452C6G2	A0A384B304	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.861
EDC3	LSM3	A0A452C6G2	A0A384A733	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.689
EDC3	LSM4	A0A452C6G2	A0A384B797	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.949
EDC3	LSM5	A0A452C6G2	A0A383ZJH3	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.679
EDC3	LSM6	A0A452C6G2	A0A384APZ2	LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3.	U6 snRNA-associated Sm-like protein LSm6.	0.688