STRINGSTRING
CCNT1 CCNT1 POLR2I POLR2I POLR2B POLR2B POLR2A POLR2A EAF1 EAF1 POLR2C POLR2C GTF2F1 GTF2F1 MLLT1 MLLT1 NCBP2 NCBP2 CTDP1 CTDP1 POLR2G POLR2G ELOA ELOA EAF2 EAF2 SUPT4H1 SUPT4H1 POLR2E POLR2E MLLT3 MLLT3 AFF1 AFF1 LOC103015962 LOC103015962 SUPT5H SUPT5H RTF1 RTF1 NELFA NELFA NELFB NELFB POLR2D POLR2D POLR2J POLR2J GTF2F2 GTF2F2 CCNT2 CCNT2 CCNH CCNH NELFE NELFE CDK9 CDK9 POLR2H POLR2H ELL ELL NCBP1 NCBP1 POLR2L POLR2L POLR2K POLR2K CCNK CCNK NELFCD NELFCD AFF4 AFF4 POLR2F POLR2F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNT1cyclin-T1 isoform X1; Belongs to the cyclin family. (727 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1963 aa)
EAF1ELL-associated factor 1. (268 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3 isoform X1. (275 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
MLLT1Protein ENL. (553 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (765 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
ELOAelongin-A. (767 aa)
EAF2ELL-associated factor 2. (264 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
MLLT3LOW QUALITY PROTEIN: protein AF-9. (605 aa)
AFF1AF4/FMR2 family member 1 isoform X1. (1230 aa)
LOC103015962DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
SUPT5HTranscription elongation factor SPT5. (1083 aa)
RTF1RNA polymerase-associated protein RTF1 homolog. (710 aa)
NELFANegative elongation factor A. (451 aa)
NELFBLOW QUALITY PROTEIN: negative elongation factor B. (761 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (104 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
CCNT2cyclin-T2 isoform X1; Belongs to the cyclin family. (745 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (328 aa)
NELFENegative elongation factor E isoform X4. (419 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ELLRNA polymerase II elongation factor ELL. (612 aa)
NCBP1Nuclear cap-binding protein subunit 1 isoform X1. (790 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (58 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
CCNKcyclin-K; Belongs to the cyclin family. (410 aa)
NELFCDNegative elongation factor C/D. (533 aa)
AFF4LOW QUALITY PROTEIN: AF4/FMR2 family member 4. (1164 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (115 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.