STRINGSTRING
SMAD1 SMAD1 ZFYVE16 ZFYVE16 AMHR2 AMHR2 ACVRL1 ACVRL1 CHRDL2 CHRDL2 SMAD5 SMAD5 SKI SKI SMAD6 SMAD6 GDF2 GDF2 ACVR1 ACVR1 BMPR1B BMPR1B SMURF2 SMURF2 SMURF1 SMURF1 BMP10 BMP10 BMPR2 BMPR2 ACVR2B ACVR2B BMP2 BMP2 SMAD4 SMAD4 SMAD7 SMAD7 SMAD9 SMAD9 NOG NOG CER1 CER1 UBE2D1 UBE2D1 BMPR1A BMPR1A ACVR2A ACVR2A FSTL1 FSTL1 CHRDL1 CHRDL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X1. (1563 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (549 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
CHRDL2Chordin-like protein 2 isoform X1. (452 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
SKISki oncogene. (772 aa)
SMAD6Mothers against decapentaplegic homolog. (321 aa)
GDF2Growth/differentiation factor 2. (432 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
SMURF2E3 ubiquitin-protein ligase. (735 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (719 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD9Mothers against decapentaplegic homolog. (440 aa)
NOGNoggin. (154 aa)
CER1Cerberus. (273 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
FSTL1Follistatin-related protein 1. (307 aa)
CHRDL1Chordin-like protein 1 isoform X1. (379 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.