STRINGSTRING
CACNA1E CACNA1E SLC2A1 SLC2A1 FFAR1 FFAR1 PLCB1 PLCB1 THAP6 THAP6 GNB1 GNB1 ACSL3 ACSL3 GNG8 GNG8 GNAI2 GNAI2 CACNA2D2 CACNA2D2 RAP1A RAP1A GNB3 GNB3 GNG4 GNG4 ADRA2C ADRA2C PRKACB PRKACB PLCB3 PLCB3 CACNA1D CACNA1D KCNJ11 KCNJ11 ABCC8 ABCC8 ADCY5 ADCY5 GNA15 GNA15 GNG7 GNG7 GNA11 GNA11 RAPGEFL1 RAPGEFL1 CACNA2D1 CACNA2D1 ADCY6 ADCY6 RAPGEF3 RAPGEF3 CACNB3 CACNB3 PLCB2 PLCB2 SYT5 SYT5 ACSL4 ACSL4 GNG13 GNG13 PRKACA PRKACA GNA14 GNA14 LOC103018216 LOC103018216 CACNA1F CACNA1F GCG GCG RAPGEF4 RAPGEF4 KCNS3 KCNS3 KCNB1 KCNB1 PRKCA PRKCA GNB2 GNB2 ITPR3 ITPR3 GNAI1 GNAI1 LOC103019875 LOC103019875 CD36 CD36 ITPR1 ITPR1 GNG2 GNG2 KCNC2 KCNC2 ITPR2 ITPR2 GNB5 GNB5 GNB4 GNB4 GNGT1 GNGT1 GNG11 GNG11 THAP7 THAP7 CACNB2 CACNB2 SLC2A2 SLC2A2 GLP1R GLP1R CACNA1S CACNA1S GNG12 GNG12 GNG5 GNG5 ADRA2A ADRA2A GNG3 GNG3 GNGT2 GNGT2 CACNA1C CACNA1C CACNA1A CACNA1A FAP FAP RAPGEF5 RAPGEF5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2331 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (480 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
THAP6THAP domain-containing protein 6 isoform X1. (222 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (296 aa)
ACSL3long-chain-fatty-acid--CoA ligase 3. (720 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1075 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ADRA2Calpha-2C adrenergic receptor. (422 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11. (396 aa)
ABCC8ATP-binding cassette sub-family C member 8 isoform X1. (1584 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
RAPGEFL1Rap guanine nucleotide exchange factor-like 1. (559 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1110 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1220 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X1. (936 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3. (539 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
SYT5Synaptotagmin-5 isoform X1. (386 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4. (686 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
LOC103018216Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
GCGGlucagon isoform X1. (180 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (858 aa)
KCNS3Potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC103019875Platelet glycoprotein 4-like; Belongs to the CD36 family. (472 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (360 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (301 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
THAP7THAP domain-containing protein 7. (313 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (446 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADRA2Aalpha-2A adrenergic receptor. (465 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa)
FAPProlyl endopeptidase FAP isoform X1; Belongs to the peptidase S9B family. (764 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (612 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (16%) [HD]