STRINGSTRING
AK2 AK2 AK4 AK4 NME3 NME3 AK6 AK6 LOC103010377 LOC103010377 NME2 NME2 TXN TXN TXNDC8 TXNDC8 AK7 AK7 TXNRD1 TXNRD1 NUDT13 NUDT13 DTYMK DTYMK GUK1 GUK1 NME9 NME9 RRM2B RRM2B NME4 NME4 CTPS2 CTPS2 RRM1 RRM1 GSR GSR CMPK1 CMPK1 CTPS1 CTPS1 DCTPP1 DCTPP1 CDADC1 CDADC1 NME8 NME8 SMIM3 SMIM3 DCTD DCTD AK9 AK9 GLRX2 GLRX2 TYMS TYMS AK5 AK5 CEP44 CEP44 AK1 AK1 AK8 AK8 SLC25A42 SLC25A42 RRM2 RRM2 TXNDC2 TXNDC2 GLRX GLRX NRSN1 NRSN1 TXNRD3 TXNRD3 CMPK2 CMPK2 LOC114236184 LOC114236184 DUT DUT LOC103002621 LOC103002621 LOC103014119 LOC103014119 LOC103000785 LOC103000785
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
NME3Nucleoside diphosphate kinase. (163 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
LOC103010377Nucleoside diphosphate kinase. (152 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
TXNDC8Thioredoxin; Belongs to the thioredoxin family. (105 aa)
AK7Adenylate kinase 7. (698 aa)
TXNRD1Thioredoxin reductase 1, cytoplasmic. (497 aa)
NUDT13Nucleoside diphosphate-linked moiety X motif 13 isoform X1. (352 aa)
DTYMKThymidylate kinase. (186 aa)
GUK1Guanylate kinase isoform X1. (214 aa)
NME9Thioredoxin domain-containing protein 6; Belongs to the NDK family. (340 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B. (351 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (607 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
GSRGlutathione reductase, mitochondrial. (410 aa)
CMPK1UMP-CMP kinase; Belongs to the adenylate kinase family. (232 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
DCTPP1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (169 aa)
CDADC1Cytidine and dCMP deaminase domain-containing protein 1 isoform X1. (565 aa)
NME8Thioredoxin domain-containing protein 3. (425 aa)
SMIM3Small integral membrane protein 3. (60 aa)
DCTDDeoxycytidylate deaminase. (178 aa)
AK9Adenylate kinase 9. (1862 aa)
GLRX2Glutaredoxin 2 isoform X1. (132 aa)
TYMSThymidylate synthase. (303 aa)
AK5Adenylate kinase isoenzyme 5 isoform X1; Belongs to the adenylate kinase family. (561 aa)
CEP44Centrosomal protein of 44 kDa. (385 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (194 aa)
AK8Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (498 aa)
SLC25A42Mitochondrial coenzyme A transporter SLC25A42 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (393 aa)
TXNDC2Thioredoxin domain-containing protein 2. (335 aa)
GLRXGlutaredoxin-1. (106 aa)
NRSN1Neurensin-1. (195 aa)
TXNRD3LOW QUALITY PROTEIN: thioredoxin reductase 3. (563 aa)
CMPK2UMP-CMP kinase 2, mitochondrial. (303 aa)
LOC114236184LOW QUALITY PROTEIN: adenylate kinase isoenzyme 1-like. (141 aa)
DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1. (288 aa)
LOC103002621LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2-like. (406 aa)
LOC103014119LOW QUALITY PROTEIN: thymidylate synthase-like. (306 aa)
LOC103000785Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like. (164 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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