STRINGSTRING
ATAD5 ATAD5 RPS27A RPS27A UBC UBC GTF2H3 GTF2H3 LIG1 LIG1 ERCC2 ERCC2 TCEA1 TCEA1 UBE2V2 UBE2V2 XAB2 XAB2 USP45 USP45 VTCN1 VTCN1 COPS7A COPS7A COPS2 COPS2 SPOCD1 SPOCD1 POLD4 POLD4 RAD23A RAD23A SUMO3 SUMO3 UBB UBB COPS3 COPS3 PRPF19 PRPF19 DDB1 DDB1 POLR2G POLR2G GTF2H1 GTF2H1 VWA5B1 VWA5B1 TCEA3 TCEA3 POLK POLK LOC103000259 LOC103000259 CDK7 CDK7 ERCC8 ERCC8 POLR2E POLR2E RPA1 RPA1 RAD23B RAD23B CUL4B CUL4B ERCC6 ERCC6 RFC1 RFC1 LOC103015962 LOC103015962 PHF3 PHF3 RPAP3 RPAP3 ISY1 ISY1 POLD1 POLD1 TCEANC TCEANC PARP2 PARP2 AQR AQR NRDE2 NRDE2 DDB2 DDB2 POLE POLE UVSSA UVSSA MEIOB MEIOB UBE2I UBE2I LOC103006290 LOC103006290 PIAS3 PIAS3 CHD1L CHD1L ERCC3 ERCC3 POLR2D POLR2D XPC XPC CETN2 CETN2 WBP1 WBP1 INO80B INO80B POLE4 POLE4 ERCC1 ERCC1 LOC103016368 LOC103016368 COPS4 COPS4 POLR2C POLR2C PARP1 PARP1 POLR2A POLR2A UBE2N UBE2N RNF111 RNF111 POLR2B POLR2B POLR2I POLR2I RPA3 RPA3 PPIE PPIE TCEANC2 TCEANC2 POLR2J POLR2J RCBTB2 RCBTB2 LOC103016635 LOC103016635 POLD2 POLD2 LOC103015513 LOC103015513 COPS7B COPS7B ERCC4 ERCC4 USP7 USP7 RBX1 RBX1 LOC103003809 LOC103003809 RFC5 RFC5 COPS6 COPS6 RFC2 RFC2 NFATC2IP NFATC2IP GTF2H5 GTF2H5 KCTD2 KCTD2 GPS1 GPS1 TCEA2 TCEA2 COPS5 COPS5 COPS8 COPS8 LOC103001445 LOC103001445 LIG3 LIG3 LOC103020561 LOC103020561 EP300 EP300 POLR2F POLR2F LOC114238515 LOC114238515 SUMO2 SUMO2 PPP1R42 PPP1R42 LOC103007401 LOC103007401 USP40 USP40 HMGN1 HMGN1 LOC103011160 LOC103011160 PARP3 PARP3 POLD3 POLD3 POLR2K POLR2K LOC102999414 LOC102999414 LOC103016069 LOC103016069 XRCC1 XRCC1 LOC114235986 LOC114235986 POLR2L POLR2L WDR76 WDR76 VWA5B2 VWA5B2 POLE3 POLE3 LOC103006878 LOC103006878 XPA XPA ERCC5 ERCC5 BIVM BIVM CUL4A CUL4A UBA52 UBA52 RFC4 RFC4 KXD1 KXD1 POLR2H POLR2H GTF2H4 GTF2H4 RCBTB1 RCBTB1 RFC3 RFC3 CCNH CCNH CETN3 CETN3 MNAT1 MNAT1 POLE2 POLE2 LOC103016861 LOC103016861 PCNA PCNA LOC103008595 LOC103008595 SUMO1 SUMO1 ZNF830 ZNF830
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATAD5ATPase family AAA domain-containing protein 5. (1853 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
UBCpolyubiquitin-C. (609 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
LIG1DNA ligase. (918 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD. (760 aa)
TCEA1Transcription elongation factor A protein 1. (266 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (105 aa)
XAB2pre-mRNA-splicing factor SYF1. (853 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (816 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1. (283 aa)
COPS7ALOW QUALITY PROTEIN: COP9 signalosome complex subunit 7a. (272 aa)
COPS2COP9 signalosome complex subunit 2 isoform X1. (450 aa)
SPOCD1SPOC domain-containing protein 1 isoform X1. (899 aa)
POLD4DNA polymerase delta subunit 4 isoform X2. (107 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (363 aa)
SUMO3Small ubiquitin-related modifier 3. (204 aa)
UBBpolyubiquitin-B. (305 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
PRPF19pre-mRNA-processing factor 19. (504 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
GTF2H1General transcription factor IIH subunit 1 isoform X1. (548 aa)
VWA5B1Von Willebrand factor A domain-containing protein 5B1. (1221 aa)
TCEA3Transcription elongation factor A protein 3. (346 aa)
POLKDNA polymerase kappa isoform X1. (877 aa)
LOC103000259General transcription factor IIH subunit. (395 aa)
CDK7Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
ERCC8DNA excision repair protein ERCC-8 isoform X1. (396 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
RAD23BUV excision repair protein RAD23 homolog B. (452 aa)
CUL4BLOW QUALITY PROTEIN: cullin-4B; Belongs to the cullin family. (893 aa)
ERCC6DNA excision repair protein ERCC-6 isoform X1. (1485 aa)
RFC1Replication factor C subunit 1. (1146 aa)
LOC103015962DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
PHF3PHD finger protein 3 isoform X1. (2043 aa)
RPAP3RNA polymerase II-associated protein 3. (665 aa)
ISY1pre-mRNA-splicing factor ISY1 homolog isoform X1. (296 aa)
POLD1DNA polymerase. (1107 aa)
TCEANCTranscription elongation factor A N-terminal and central domain-containing protein. (352 aa)
PARP2Poly [ADP-ribose] polymerase. (564 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1485 aa)
NRDE2Protein NRDE2 homolog. (1160 aa)
DDB2DNA damage-binding protein 2 isoform X1. (457 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
UVSSAUV-stimulated scaffold protein A. (679 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X1. (471 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC103006290Non-histone chromosomal protein HMG-14. (101 aa)
PIAS3E3 SUMO-protein ligase PIAS3 isoform X1. (628 aa)
CHD1Lchromodomain-helicase-DNA-binding protein 1-like isoform X1. (904 aa)
ERCC3General transcription and DNA repair factor IIH helicase subunit XPB. (782 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (104 aa)
XPCDNA repair protein complementing XP-C cells. (962 aa)
CETN2Centrin-2. (204 aa)
WBP1WW domain-binding protein 1. (249 aa)
INO80BINO80 complex subunit B isoform X2. (373 aa)
POLE4DNA polymerase epsilon subunit 4. (116 aa)
ERCC1DNA excision repair protein ERCC-1. (294 aa)
LOC103016368DNA repair protein XRCC1-like isoform X1. (340 aa)
COPS4COP9 signalosome complex subunit 4 isoform X1. (406 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3 isoform X1. (275 aa)
PARP1Poly [ADP-ribose] polymerase. (1021 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1963 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (224 aa)
RNF111E3 ubiquitin-protein ligase Arkadia isoform X1. (1028 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
RPA3Replication protein A 14 kDa subunit isoform X1. (121 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
RCBTB2RCC1 and BTB domain-containing protein 2 isoform X1. (572 aa)
LOC103016635LOW QUALITY PROTEIN: uroplakin-3b-like protein 1. (254 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
LOC103015513Small ubiquitin-related modifier. (95 aa)
COPS7BCOP9 signalosome complex subunit 7b isoform X1. (343 aa)
ERCC4DNA repair endonuclease XPF. (916 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1055 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
LOC103003809Small ubiquitin-related modifier 2-like. (75 aa)
RFC5Replication factor C subunit 5. (341 aa)
COPS6COP9 signalosome complex subunit 6. (308 aa)
RFC2Replication factor C subunit 2. (352 aa)
NFATC2IPNFATC2-interacting protein. (418 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (224 aa)
GPS1COP9 signalosome complex subunit 1 isoform X1. (471 aa)
TCEA2Transcription elongation factor A protein 2. (273 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
COPS8COP9 signalosome complex subunit 8. (209 aa)
LOC103001445LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
LIG3DNA ligase. (1031 aa)
LOC103020561LOW QUALITY PROTEIN: CDK-activating kinase assembly factor MAT1-like. (454 aa)
EP300Histone acetyltransferase p300. (2445 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (115 aa)
LOC114238515Non-histone chromosomal protein HMG-14-like. (101 aa)
SUMO2Small ubiquitin-related modifier. (111 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42 isoform X1. (357 aa)
LOC103007401Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (230 aa)
USP40Ubiquitin carboxyl-terminal hydrolase 40 isoform X1; Belongs to the peptidase C19 family. (1241 aa)
HMGN1Non-histone chromosomal protein HMG-14. (192 aa)
LOC103011160Ubiquitin-like. (144 aa)
PARP3Poly [ADP-ribose] polymerase. (470 aa)
POLD3DNA polymerase delta subunit 3 isoform X1. (465 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
LOC102999414Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (235 aa)
LOC103016069Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (287 aa)
XRCC1DNA repair protein XRCC1. (536 aa)
LOC114235986LOW QUALITY PROTEIN: non-histone chromosomal protein HMG-14-like. (101 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (58 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (632 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2 isoform X1. (1295 aa)
POLE3LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 3. (146 aa)
LOC103006878Non-histone chromosomal protein HMG-17-like. (90 aa)
XPADNA repair protein complementing XP-A cells. (273 aa)
ERCC5DNA repair protein complementing XP-G cells isoform X1. (1201 aa)
BIVMBasic immunoglobulin-like variable motif-containing protein isoform X3. (504 aa)
CUL4Acullin-4A; Belongs to the cullin family. (637 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
RFC4Replication factor C subunit 4. (376 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
RCBTB1RCC1 and BTB domain-containing protein 1 isoform X1. (549 aa)
RFC3Replication factor C subunit 3. (356 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (328 aa)
CETN3Centrin-3. (167 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
LOC103016861Small ubiquitin-related modifier 2-like. (76 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
LOC103008595Non-histone chromosomal protein HMG-17. (90 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ZNF830Zinc finger protein 830. (380 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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