STRINGSTRING
POLR2H POLR2H RNGTT RNGTT RNMT RNMT NCBP1 NCBP1 POLR2L POLR2L KHDC3L KHDC3L POLR2A POLR2A POLR2B POLR2B POLR2I POLR2I POLR2K POLR2K POLR2C POLR2C ERCC2 ERCC2 GTF2F1 GTF2F1 POLR2F POLR2F LOC103020561 LOC103020561 POLR2G POLR2G LOC103000158 LOC103000158 GTF2H1 GTF2H1 LOC103000259 LOC103000259 CDK7 CDK7 POLR2E POLR2E LOC103015962 LOC103015962 SUPT5H SUPT5H ERCC3 ERCC3 POLR2D POLR2D GTF2H5 GTF2H5 POLR2J POLR2J GTF2F2 GTF2F2 LOC103016635 LOC103016635 DUSP11 DUSP11 GTF2H3 GTF2H3 MNAT1 MNAT1 CCNH CCNH GTF2H4 GTF2H4 NCBP2 NCBP2 CUNH6orf15 CUNH6orf15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (610 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (477 aa)
NCBP1Nuclear cap-binding protein subunit 1 isoform X1. (790 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (58 aa)
KHDC3LKHDC3-like protein. (203 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1963 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3 isoform X1. (275 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD. (760 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (115 aa)
LOC103020561LOW QUALITY PROTEIN: CDK-activating kinase assembly factor MAT1-like. (454 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
LOC103000158RNA/RNP complex-1-interacting phosphatase-like. (109 aa)
GTF2H1General transcription factor IIH subunit 1 isoform X1. (548 aa)
LOC103000259General transcription factor IIH subunit. (395 aa)
CDK7Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
LOC103015962DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
SUPT5HTranscription elongation factor SPT5. (1083 aa)
ERCC3General transcription and DNA repair factor IIH helicase subunit XPB. (782 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (104 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
LOC103016635LOW QUALITY PROTEIN: uroplakin-3b-like protein 1. (254 aa)
DUSP11RNA/RNP complex-1-interacting phosphatase. (120 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (328 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
CUNH6orf15Uncharacterized protein C6orf15 homolog. (317 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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