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SLC27A3 SLC27A3 MORC2 MORC2 ACSL3 ACSL3 ELOVL4 ELOVL4 ACSBG2 ACSBG2 SLC27A2 SLC27A2 ACSF3 ACSF3 ACSL5 ACSL5 ACSBG1 ACSBG1 ELOVL2 ELOVL2 HACD2 HACD2 ELOVL7 ELOVL7 HACD4 HACD4 HSD17B3 HSD17B3 LOC103009790 LOC103009790 ACSL1 ACSL1 LOC103003294 LOC103003294 MORC4 MORC4 HSD17B12 HSD17B12 ACSL4 ACSL4 TECR TECR HSDL1 HSDL1 LOC102998571 LOC102998571 LOC102999763 LOC102999763 SLC25A1 SLC25A1 PPT2 PPT2 LOC103019841 LOC103019841 OLAH OLAH HACD1 HACD1 ELOVL5 ELOVL5 TECRL TECRL CBR4 CBR4 ELOVL6 ELOVL6 ACACA ACACA ACSL6 ACSL6 SCD SCD ELOVL3 ELOVL3 HSD17B8 HSD17B8 LOC103017465 LOC103017465 ARMC7 ARMC7 MORC3 MORC3 SCD5 SCD5 PPT1 PPT1 HACD3 HACD3 ELOVL1 ELOVL1 HTD2 HTD2 LOC114238847 LOC114238847 MORC1 MORC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC27A3Solute carrier family 27 member 3 isoform X1. (446 aa)
MORC2MORC family CW-type zinc finger protein 2. (1015 aa)
ACSL3long-chain-fatty-acid--CoA ligase 3. (720 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
ACSBG2long-chain-fatty-acid--CoA ligase ACSBG2. (654 aa)
SLC27A2Very long-chain acyl-CoA synthetase. (620 aa)
ACSF3acyl-CoA synthetase family member 3, mitochondrial. (587 aa)
ACSL5long-chain-fatty-acid--CoA ligase 5. (682 aa)
ACSBG1long-chain-fatty-acid--CoA ligase ACSBG1 isoform X1. (740 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (360 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa)
HSD17B3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
LOC103009790ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa)
ACSL1long-chain-fatty-acid--CoA ligase 1. (698 aa)
LOC103003294ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
MORC4MORC family CW-type zinc finger protein 4 isoform X3. (845 aa)
HSD17B12Very-long-chain 3-oxoacyl-CoA reductase isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4. (686 aa)
TECRVery-long-chain enoyl-CoA reductase. (344 aa)
HSDL1Inactive hydroxysteroid dehydrogenase-like protein 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
LOC102998571Elongation of very long chain fatty acids protein. (120 aa)
LOC102999763LOW QUALITY PROTEIN: very-long-chain 3-oxoacyl-CoA reductase-B-like. (339 aa)
SLC25A1Tricarboxylate transport protein, mitochondrial; Belongs to the mitochondrial carrier (TC 2.A.29) family. (387 aa)
PPT2LOW QUALITY PROTEIN: lysosomal thioesterase PPT2. (317 aa)
LOC103019841stearoyl-CoA desaturase 5-like. (74 aa)
OLAHLOW QUALITY PROTEIN: S-acyl fatty acid synthase thioesterase, medium chain. (260 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (195 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
TECRLtrans-2,3-enoyl-CoA reductase-like isoform X1. (363 aa)
CBR4Carbonyl reductase family member 4 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
ACACAacetyl-CoA carboxylase 1 isoform X1. (2383 aa)
ACSL6long-chain-fatty-acid--CoA ligase 6 isoform X1. (746 aa)
SCDacyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8. (259 aa)
LOC103017465Fatty acid synthase-like isoform X1. (3457 aa)
ARMC7Armadillo repeat-containing protein 7 isoform X1. (234 aa)
MORC3MORC family CW-type zinc finger protein 3. (933 aa)
SCD5stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (308 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (314 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2, mitochondrial. (168 aa)
LOC114238847LOW QUALITY PROTEIN: palmitoyl-protein thioesterase 1-like. (237 aa)
MORC1LOW QUALITY PROTEIN: MORC family CW-type zinc finger protein 1. (991 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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