STRINGSTRING
LOC103015848 LOC103015848 PSMC2 PSMC2 HIPK2 HIPK2 LOC103009986 LOC103009986 LOC103003105 LOC103003105 TCF3 TCF3 CDK7 CDK7 PSMC5 PSMC5 WDR5B WDR5B SMARCD2 SMARCD2 PSMA1 PSMA1 UBB UBB TMEM62 TMEM62 SCML1 SCML1 PSMA4 PSMA4 LOC103019280 LOC103019280 LMO1 LMO1 ZFPM1 ZFPM1 IL2 IL2 ELF2 ELF2 PSMD13 PSMD13 CCND1 CCND1 HDAC1 HDAC1 ARID1A ARID1A PRMT8 PRMT8 CCND2 CCND2 LOC103000493 LOC103000493 PSMA5 PSMA5 PRMT6 PRMT6 SMARCC1 SMARCC1 LOC103011976 LOC103011976 CSNK2A2 CSNK2A2 GATA3 GATA3 LDB2 LDB2 RNF2 RNF2 PSMB6 PSMB6 TP73 TP73 LOC103019413 LOC103019413 KMT2C KMT2C SMARCD3 SMARCD3 KMT2B KMT2B SCMH1 SCMH1 LOC103020561 LOC103020561 CBFB CBFB PSMD7 PSMD7 SMARCA4 SMARCA4 PTPN11 PTPN11 TAL1 TAL1 LOC103015084 LOC103015084 SCML2 SCML2 PBRM1 PBRM1 LOC103019119 LOC103019119 LOC103013996 LOC103013996 LOC103020690 LOC103020690 LOC103009898 LOC103009898 LOC102998612 LOC102998612 LOC103008837 LOC103008837 KMT2D KMT2D SMARCC2 SMARCC2 LOC103011160 LOC103011160 LOC103003208 LOC103003208 LMO2 LMO2 SMARCA2 SMARCA2 ARID1B ARID1B AUTS2 AUTS2 SETD1A SETD1A LOC114238483 LOC114238483 LOC103008474 LOC103008474 CBX6 CBX6 EP300 EP300 SETD1B SETD1B PAX8 PAX8 ESR1 ESR1 LOC103015272 LOC103015272 PSMB10 PSMB10 CCND3 CCND3 SIN3A SIN3A PML PML PSMA8 PSMA8 PHC3 PHC3 PAX5 PAX5 KMT2A KMT2A LOC102997204 LOC102997204 CLDN5 CLDN5 PSMD10 PSMD10 SMARCB1 SMARCB1 PHC1 PHC1 CDK6 CDK6 SIN3B SIN3B UBA52 UBA52 ACTL6A ACTL6A TCF12 TCF12 WDR5 WDR5 LMO3 LMO3 PSMB7 PSMB7 ABL1 ABL1 CSNK2B CSNK2B LY6G5B LY6G5B PSMF1 PSMF1 CSNK2A1 CSNK2A1 ITCH ITCH CCNH CCNH MNAT1 MNAT1 PSMA3 PSMA3 PSMC6 PSMC6 SOCS4 SOCS4 BLK BLK SETD5 SETD5 RYBP RYBP PSMD6 PSMD6 DPY30 DPY30 MYB MYB PSMD11 PSMD11 PSME4 PSME4 RPS27A RPS27A BMI1 BMI1 UBC UBC PSMD9 PSMD9 TNRC6B TNRC6B LOC103019984 LOC103019984 LOC103002779 LOC103002779 PSMA2 PSMA2 PCGF5 PCGF5 PAX2 PAX2 LDB1 LDB1 PSMB9 PSMB9 LOC103012429 LOC103012429 PSMB8 PSMB8 RING1 RING1 ELF1 ELF1 LOC103002948 LOC103002948 LOC103002676 LOC103002676 PSMB1 PSMB1 CBX2 CBX2 PSMD12 PSMD12 LOC103005469 LOC103005469 CBX4 CBX4 CBX8 CBX8 PSMA7 PSMA7 PRMT1 PRMT1 PSMD1 PSMD1 LOC103018418 LOC103018418 RUNX1 RUNX1 PSMD14 PSMD14 KAT2B KAT2B RBBP5 RBBP5 FOXP3 FOXP3 PHC2 PHC2 PSMB2 PSMB2 CREBBP CREBBP SPI1 SPI1 PSMC3 PSMC3 ELF4 ELF4 PSMC1 PSMC1 PSMA6 PSMA6 PSME1 PSME1 PSME2 PSME2 LOC114235831 LOC114235831 PSMB5 PSMB5 PSMB11 PSMB11 SPIB SPIB PSMD8 PSMD8 PSMC4 PSMC4 SMARCD1 SMARCD1 ARID2 ARID2 LOC103003205 LOC103003205 GATA2 GATA2 LOC103010782 LOC103010782 LOC103004316 LOC103004316 LOC103010190 LOC103010190 LOC103004037 LOC103004037 LOC102998884 LOC102998884 ASH2L ASH2L LOC103017256 LOC103017256 PSMD5 PSMD5 PSMD4 PSMD4 PSMB4 PSMB4 CTSK CTSK LOC103018846 LOC103018846 LOC103018297 LOC103018297 LOC103019385 LOC103019385 LOC103001388 LOC103001388 PSMD3 PSMD3 SMARCE1 SMARCE1 LOC103019838 LOC103019838 LOC103016974 LOC103016974 PSMB3 PSMB3 LOC103020116 LOC103020116 LOC103020394 LOC103020394 LOC103014184 LOC103014184 LOC103019568 LOC103019568 LOC103015570 LOC103015570 LOC103018292 LOC103018292 KMT2E KMT2E
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103015848Histone H2A; Belongs to the histone H2A family. (130 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1207 aa)
LOC103009986Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
LOC103003105Cathepsin L1 isoform X1; Belongs to the peptidase C1 family. (333 aa)
TCF3Transcription factor E2-alpha isoform X4. (645 aa)
CDK7Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
WDR5BWD repeat-containing protein 5B isoform X1. (329 aa)
SMARCD2annotation not available (456 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
UBBpolyubiquitin-B. (305 aa)
TMEM62Transmembrane protein 62 isoform X1. (656 aa)
SCML1Sex comb on midleg-like protein 1 isoform X1. (341 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
LOC103019280Histone H2A; Belongs to the histone H2A family. (128 aa)
LMO1Rhombotin-1. (147 aa)
ZFPM1Zinc finger protein ZFPM1. (874 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
ELF2ETS-related transcription factor Elf-2 isoform X1. (607 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
CCND1G1/S-specific cyclin-D1 isoform X1; Belongs to the cyclin family. (214 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
ARID1AAT-rich interactive domain-containing protein 1A isoform X1. (1904 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (425 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
LOC103000493Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PRMT6Protein arginine N-methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
SMARCC1SWI/SNF complex subunit SMARCC1. (996 aa)
LOC103011976YY1-associated factor 2. (212 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
LDB2LIM domain-binding protein 2 isoform X1. (373 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (344 aa)
PSMB6Proteasome subunit beta. (239 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa)
LOC103019413Histone H2B; Belongs to the histone H2B family. (122 aa)
KMT2CHistone-lysine N-methyltransferase 2C. (4930 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (483 aa)
KMT2BLOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B. (2618 aa)
SCMH1Polycomb protein SCMH1 isoform X1. (649 aa)
LOC103020561LOW QUALITY PROTEIN: CDK-activating kinase assembly factor MAT1-like. (454 aa)
CBFBCore-binding factor subunit beta. (151 aa)
PSMD7LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 7. (326 aa)
SMARCA4Transcription activator BRG1 isoform X1. (1648 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
TAL1T-cell acute lymphocytic leukemia protein 1. (172 aa)
LOC103015084LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1A-like. (754 aa)
SCML2Sex comb on midleg-like protein 2. (621 aa)
PBRM1Protein polybromo-1 isoform X1. (1718 aa)
LOC103019119Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103013996Proteasome subunit alpha type. (284 aa)
LOC103020690Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103009898Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102998612Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103008837Histone H3.1-like isoform X1. (165 aa)
KMT2DLOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D. (5534 aa)
SMARCC2SWI/SNF complex subunit SMARCC2. (1140 aa)
LOC103011160Ubiquitin-like. (144 aa)
LOC103003208LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RING1-like. (406 aa)
LMO2Rhombotin-2 isoform X1. (158 aa)
SMARCA2Probable global transcription activator SNF2L2 isoform X1. (1631 aa)
ARID1BAT-rich interactive domain-containing protein 1B isoform X3. (1779 aa)
AUTS2Autism susceptibility gene 2 protein. (739 aa)
SETD1AHistone-lysine N-methyltransferase SETD1A. (1494 aa)
LOC114238483Tyrosine-protein phosphatase non-receptor type 11-like. (194 aa)
LOC103008474Tyrosine-protein phosphatase non-receptor type 11-like isoform X1. (509 aa)
CBX6Chromobox protein homolog 6 isoform X1. (415 aa)
EP300Histone acetyltransferase p300. (2445 aa)
SETD1BHistone-lysine N-methyltransferase SETD1B. (1934 aa)
PAX8Paired box protein Pax-8 isoform X1. (458 aa)
ESR1LOW QUALITY PROTEIN: estrogen receptor. (422 aa)
LOC103015272LOW QUALITY PROTEIN: LIM domain-binding protein 2-like. (246 aa)
PSMB10Proteasome subunit beta. (273 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa)
SIN3APaired amphipathic helix protein Sin3a. (1274 aa)
PMLProtein PML isoform X1. (871 aa)
PSMA8Proteasome subunit alpha type. (265 aa)
PHC3Polyhomeotic-like protein 3 isoform X1. (1012 aa)
PAX5Paired box protein Pax-5. (390 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3905 aa)
LOC102997204Histone H2A; Belongs to the histone H2A family. (129 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
PHC1Polyhomeotic-like protein 1. (997 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
SIN3BPaired amphipathic helix protein Sin3b isoform X1. (1075 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (468 aa)
TCF12Transcription factor 12 isoform X1. (706 aa)
WDR5WD repeat-containing protein 5. (334 aa)
LMO3LIM domain only protein 3 isoform X1. (156 aa)
PSMB7Proteasome subunit beta. (277 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (218 aa)
PSMF1Proteasome inhibitor PI31 subunit. (270 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (328 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
BLKTyrosine-protein kinase. (501 aa)
SETD5SET domain-containing protein 5 isoform X1. (1497 aa)
RYBPRING1 and YY1-binding protein. (228 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
DPY30Protein dpy-30 homolog. (99 aa)
MYBTranscriptional activator Myb. (855 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (429 aa)
PSME4Proteasome activator complex subunit 4 isoform X1. (1845 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
UBCpolyubiquitin-C. (609 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X5. (1867 aa)
LOC103019984Interleukin-3. (144 aa)
LOC103002779Histone H2A; Belongs to the histone H2A family. (168 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PCGF5Polycomb group RING finger protein 5 isoform X1. (256 aa)
PAX2Paired box protein Pax-2 isoform X1. (463 aa)
LDB1LIM domain-binding protein 1 isoform X2. (375 aa)
PSMB9Proteasome subunit beta type-9. (322 aa)
LOC103012429Autism susceptibility gene 2 protein-like. (173 aa)
PSMB8Proteasome subunit beta. (276 aa)
RING1E3 ubiquitin-protein ligase RING1. (406 aa)
ELF1ETS-related transcription factor Elf-1 isoform X1. (614 aa)
LOC103002948Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103002676Histone H2B type 1-A-like; Belongs to the histone H2B family. (126 aa)
PSMB1Proteasome subunit beta. (241 aa)
CBX2Chromobox protein homolog 2. (494 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (434 aa)
LOC103005469Late histone H2B.L4-like; Belongs to the histone H2B family. (140 aa)
CBX4E3 SUMO-protein ligase CBX4. (454 aa)
CBX8Chromobox protein homolog 8. (371 aa)
PSMA7Proteasome endopeptidase complex. (220 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC103018418Histone H2A; Belongs to the histone H2A family. (109 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (457 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
KAT2BHistone acetyltransferase KAT2B. (703 aa)
RBBP5Retinoblastoma-binding protein 5 isoform X1. (538 aa)
FOXP3LOW QUALITY PROTEIN: forkhead box protein P3. (432 aa)
PHC2LOW QUALITY PROTEIN: polyhomeotic-like protein 2. (851 aa)
PSMB2Proteasome subunit beta. (201 aa)
CREBBPCREB-binding protein isoform X1. (2444 aa)
SPI1Transcription factor PU.1 isoform X1. (271 aa)
PSMC326S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa)
ELF4ETS-related transcription factor Elf-4. (658 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
LOC114235831Estrogen receptor-like. (144 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMB11Proteasome subunit beta. (291 aa)
SPIBTranscription factor Spi-B isoform X1. (261 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
SMARCD1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1. (476 aa)
ARID2AT-rich interactive domain-containing protein 2. (1687 aa)
LOC103003205Histone H2B; Belongs to the histone H2B family. (126 aa)
GATA2LOW QUALITY PROTEIN: endothelial transcription factor GATA-2. (479 aa)
LOC103010782Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103004316Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103010190Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103004037LOW QUALITY PROTEIN: putative histone H2B type 2-D; Belongs to the histone H2B family. (130 aa)
LOC102998884Histone H2B; Belongs to the histone H2B family. (126 aa)
ASH2Lset1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1. (630 aa)
LOC103017256Histone H2B; Belongs to the histone H2B family. (143 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
LOC103018846Histone H2A; Belongs to the histone H2A family. (147 aa)
LOC103018297Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103019385Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC103001388Proteasome activator complex subunit 3. (254 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
LOC103019838Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103016974Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMB3Proteasome subunit beta. (205 aa)
LOC103020116Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103020394Histone H3.1-like. (136 aa)
LOC103014184Histone H3; Belongs to the histone H3 family. (150 aa)
LOC103019568Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103015570Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103018292Histone H2B type 1-L-like; Belongs to the histone H2B family. (154 aa)
KMT2EInactive histone-lysine N-methyltransferase 2E. (1786 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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