STRINGSTRING
LOC103018596 LOC103018596 NOS3 NOS3 PRKG2 PRKG2 PDSS1 PDSS1 LOC103011186 LOC103011186 COQ9 COQ9 COQ2 COQ2 ITPRIP ITPRIP GCHFR GCHFR PTS PTS SPR SPR COQ5 COQ5 COQ6 COQ6 LOC103007417 LOC103007417 IDH1 IDH1 COQ7 COQ7 ITPRIPL2 ITPRIPL2 CALM2 CALM2 PDSS2 PDSS2 GCH1 GCH1 COQ3 COQ3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103018596Calmodulin-like; Belongs to the calmodulin family. (149 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1206 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PDSS1Decaprenyl-diphosphate synthase subunit 1 isoform X1; Belongs to the FPP/GGPP synthase family. (365 aa)
LOC103011186Myosin light chain 6B-like; Belongs to the calmodulin family. (366 aa)
COQ9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (317 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (374 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor-interacting protein. (556 aa)
GCHFRGTP cyclohydrolase 1 feedback regulatory protein. (84 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
SPRSepiapterin reductase. (267 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (469 aa)
LOC103007417Cytochrome c oxidase assembly factor 1 homolog isoform X1. (136 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (216 aa)
ITPRIPL2Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
PDSS2Decaprenyl-diphosphate synthase subunit 2 isoform X1; Belongs to the FPP/GGPP synthase family. (395 aa)
GCH1GTP cyclohydrolase 1. (249 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (369 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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