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TRPM1 TRPM1 TRPM4 TRPM4 TRPM7 TRPM7 RYR2 RYR2 TPCN1 TPCN1 TPCN2 TPCN2 HCN3 HCN3 PKD2L2 PKD2L2 CNGA4 CNGA4 TRPM2 TRPM2 TRPV2 TRPV2 CACNA1D CACNA1D CACNA1G CACNA1G TRPV1 TRPV1 TRPV3 TRPV3 CATSPER4 CATSPER4 CNGA2 CNGA2 SCN8A SCN8A TRPV4 TRPV4 CNGA1 CNGA1 RYR3 RYR3 SLC9C1 SLC9C1 CACNA1H CACNA1H TRPM6 TRPM6 CACNA1F CACNA1F TRPC5 TRPC5 LOC103019313 LOC103019313 SCN9A SCN9A LOC102998353 LOC102998353 SCN7A SCN7A TRPV5 TRPV5 TRPM8 TRPM8 TRPV6 TRPV6 TRPA1 TRPA1 ITPR3 ITPR3 TRPC1 TRPC1 PKDREJ PKDREJ HVCN1 HVCN1 SCN11A SCN11A SCN10A SCN10A SCN5A SCN5A ITPR1 ITPR1 TRPC4 TRPC4 ITPR2 ITPR2 CNGA3 CNGA3 LOC103017170 LOC103017170 HCN4 HCN4 HCN1 HCN1 CATSPER2 CATSPER2 CACNA1S CACNA1S NALCN NALCN CNGB1 CNGB1 TRPM5 TRPM5 SCN4A SCN4A HCN2 HCN2 CACNA1C CACNA1C RYR1 RYR1 CACNA1A CACNA1A TRPM3 TRPM3 CACNA1B CACNA1B SCN3A SCN3A PKD2 PKD2 PKD2L1 PKD2L1 CACNA1E CACNA1E CACNA1I CACNA1I
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRPM1Transient receptor potential cation channel subfamily M member 1. (956 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4 isoform X1. (1206 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7 isoform X1. (1867 aa)
RYR2Ryanodine receptor 2 isoform X1. (4884 aa)
TPCN1Two pore calcium channel protein 1 isoform X1. (826 aa)
TPCN2Two pore calcium channel protein 2 isoform X1. (747 aa)
HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 isoform X1. (786 aa)
PKD2L2Polycystic kidney disease 2-like 2 protein. (630 aa)
CNGA4Cyclic nucleotide-gated cation channel alpha-4. (575 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1502 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
TRPV3LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (819 aa)
CATSPER4Cation channel sperm-associated protein 4. (450 aa)
CNGA2Cyclic nucleotide-gated olfactory channel. (664 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
CNGA1cGMP-gated cation channel alpha-1. (689 aa)
RYR3LOW QUALITY PROTEIN: ryanodine receptor 3. (4927 aa)
SLC9C1Sodium/hydrogen exchanger 10. (1187 aa)
CACNA1HLOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2326 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6 isoform X1. (2036 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
TRPC5Short transient receptor potential channel 5. (640 aa)
LOC103019313Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
LOC102998353Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1684 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (731 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6 isoform X3; Belongs to the transient receptor (TC 1.A.4) family. (721 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1314 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
TRPC1Short transient receptor potential channel 1 isoform X3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
PKDREJPolycystic kidney disease and receptor for egg jelly-related protein. (1480 aa)
HVCN1Voltage-gated hydrogen channel 1 isoform X1. (300 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1784 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1992 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
TRPC4Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
CNGA3Cyclic nucleotide-gated cation channel alpha-3. (706 aa)
LOC103017170Two pore calcium channel protein 2-like. (763 aa)
HCN4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (813 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (735 aa)
CATSPER2LOW QUALITY PROTEIN: cation channel sperm-associated protein 2. (529 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
NALCNLOW QUALITY PROTEIN: sodium leak channel non-selective protein. (1766 aa)
CNGB1Cyclic nucleotide-gated cation channel beta-1. (1322 aa)
TRPM5LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 5. (1362 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1832 aa)
HCN2Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (573 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
RYR1Ryanodine receptor 1. (4841 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3 isoform X1. (1756 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2153 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1961 aa)
PKD2Polycystin-2. (763 aa)
PKD2L1LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein. (683 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2331 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2076 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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