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CPT2 CPT2 SCP2 SCP2 LOC103000849 LOC103000849 LOC103000297 LOC103000297 ME1 ME1 SCD5 SCD5 GK2 GK2 ACSL3 ACSL3 ME3 ME3 LOC102998844 LOC102998844 ANGPTL4 ANGPTL4 ACSBG2 ACSBG2 PLIN5 PLIN5 DBI DBI PLIN4 PLIN4 HMGCS2 HMGCS2 SLC27A2 SLC27A2 FABP3 FABP3 CPT1A CPT1A FABP6 FABP6 APOA2 APOA2 ACOX3 ACOX3 FABP2 FABP2 ILK ILK ACSL5 ACSL5 ACSBG1 ACSBG1 FADS2 FADS2 GK GK FABP1 FABP1 SLC27A5 SLC27A5 AQP7 AQP7 PLIN2 PLIN2 ACSL1 ACSL1 PCK2 PCK2 NR1H3 NR1H3 ACSL4 ACSL4 PDPK1 PDPK1 ACADM ACADM LPL LPL CPT1C CPT1C LOC103005192 LOC103005192 FABP5 FABP5 PLTP PLTP ACOX1 ACOX1 RXRB RXRB LOC103019875 LOC103019875 CD36 CD36 SCD SCD SORBS1 SORBS1 LOC102999025 LOC102999025 ACADL ACADL SLC27A6 SLC27A6 ACSL6 ACSL6 UCP1 UCP1 PPARA PPARA UBC UBC FABP7 FABP7 RXRG RXRG MMP1 MMP1 ACAA1 ACAA1 ACOX2 ACOX2 PPARG PPARG LOC103000983 LOC103000983 RXRA RXRA SLC27A4 SLC27A4 EHHADH EHHADH ADIPOQ ADIPOQ SLC27A1 SLC27A1 HMGCS1 HMGCS1 OLR1 OLR1 APOC3 APOC3 PPARD PPARD APOA5 APOA5 PCK1 PCK1 CPT1B CPT1B APOA1 APOA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPT2Carnitine O-palmitoyltransferase 2, mitochondrial isoform X1; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
SCP2Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
LOC103000849Taurochenodeoxycholic 6 alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
LOC103000297Taurochenodeoxycholic 6 alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
ME1Malic enzyme. (546 aa)
SCD5stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (308 aa)
GK2Glycerol kinase 2; Belongs to the FGGY kinase family. (553 aa)
ACSL3long-chain-fatty-acid--CoA ligase 3. (720 aa)
ME3Malic enzyme. (752 aa)
LOC102998844Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
ANGPTL4Angiopoietin-related protein 4. (412 aa)
ACSBG2long-chain-fatty-acid--CoA ligase ACSBG2. (654 aa)
PLIN5Perilipin; Belongs to the perilipin family. (404 aa)
DBIacyl-CoA-binding protein. (87 aa)
PLIN4Perilipin-4. (1932 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (437 aa)
SLC27A2Very long-chain acyl-CoA synthetase. (620 aa)
FABP3Fatty acid-binding protein, heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
FABP6Gastrotropin. (128 aa)
APOA2Apolipoprotein A-II isoform X1. (103 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
FABP2Fatty acid-binding protein, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
ILKIntegrin-linked protein kinase. (452 aa)
ACSL5long-chain-fatty-acid--CoA ligase 5. (682 aa)
ACSBG1long-chain-fatty-acid--CoA ligase ACSBG1 isoform X1. (740 aa)
FADS2acyl-CoA 6-desaturase. (413 aa)
GKGlycerol kinase isoform X1; Belongs to the FGGY kinase family. (587 aa)
FABP1Fatty acid-binding protein, liver. (127 aa)
SLC27A5LOW QUALITY PROTEIN: bile acyl-CoA synthetase. (690 aa)
AQP7Aquaporin-7 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
PLIN2Perilipin; Belongs to the perilipin family. (455 aa)
ACSL1long-chain-fatty-acid--CoA ligase 1. (698 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4. (686 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (421 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (801 aa)
LOC103005192Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
FABP5Fatty acid-binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
PLTPPhospholipid transfer protein. (496 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
RXRBRetinoic acid receptor RXR-beta isoform X1. (537 aa)
LOC103019875Platelet glycoprotein 4-like; Belongs to the CD36 family. (472 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
SCDacyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
SORBS1Sorbin and SH3 domain-containing protein 1 isoform X1. (1551 aa)
LOC102999025Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (537 aa)
ACADLLong-chain specific acyl-CoA dehydrogenase, mitochondrial. (430 aa)
SLC27A6Long-chain fatty acid transport protein 6. (632 aa)
ACSL6long-chain-fatty-acid--CoA ligase 6 isoform X1. (746 aa)
UCP1Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (274 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
UBCpolyubiquitin-C. (609 aa)
FABP7Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
RXRGRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
MMP1Interstitial collagenase. (470 aa)
ACAA13-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (678 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
LOC1030009835-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
RXRARetinoic acid receptor RXR-alpha. (439 aa)
SLC27A4Long-chain fatty acid transport protein 4. (643 aa)
EHHADHPeroxisomal bifunctional enzyme isoform X1. (723 aa)
ADIPOQAdiponectin. (243 aa)
SLC27A1Long-chain fatty acid transport protein 1 isoform X1. (646 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
OLR1Oxidized low-density lipoprotein receptor 1 isoform X1. (274 aa)
APOC3Apolipoprotein C-III. (99 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
APOA5Apolipoprotein A-V isoform X1. (378 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (780 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (265 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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