STRINGSTRING
RPA3 RPA3 ERCC1 ERCC1 LIG1 LIG1 ERCC2 ERCC2 RPA2 RPA2 POLD4 POLD4 RAD23A RAD23A DDB1 DDB1 GTF2H1 GTF2H1 LOC103000259 LOC103000259 CDK7 CDK7 ERCC8 ERCC8 RPA1 RPA1 RAD23B RAD23B CUL4B CUL4B ERCC6 ERCC6 RFC1 RFC1 POLD1 POLD1 RPA4 RPA4 DDB2 DDB2 POLE POLE ERCC3 ERCC3 XPC XPC CETN2 CETN2 POLE4 POLE4 GTF2H5 GTF2H5 RFC2 RFC2 POLD2 POLD2 ERCC4 ERCC4 RBX1 RBX1 RFC5 RFC5 GTF2H3 GTF2H3 PCNA PCNA POLE2 POLE2 MNAT1 MNAT1 CCNH CCNH RFC3 RFC3 GTF2H4 GTF2H4 RFC4 RFC4 CUL4A CUL4A ERCC5 ERCC5 XPA XPA POLE3 POLE3 POLD3 POLD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA3Replication protein A 14 kDa subunit isoform X1. (121 aa)
ERCC1DNA excision repair protein ERCC-1. (294 aa)
LIG1DNA ligase. (918 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD. (760 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
POLD4DNA polymerase delta subunit 4 isoform X2. (107 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (363 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
GTF2H1General transcription factor IIH subunit 1 isoform X1. (548 aa)
LOC103000259General transcription factor IIH subunit. (395 aa)
CDK7Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
ERCC8DNA excision repair protein ERCC-8 isoform X1. (396 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
RAD23BUV excision repair protein RAD23 homolog B. (452 aa)
CUL4BLOW QUALITY PROTEIN: cullin-4B; Belongs to the cullin family. (893 aa)
ERCC6DNA excision repair protein ERCC-6 isoform X1. (1485 aa)
RFC1Replication factor C subunit 1. (1146 aa)
POLD1DNA polymerase. (1107 aa)
RPA4Replication protein A 30 kDa subunit. (259 aa)
DDB2DNA damage-binding protein 2 isoform X1. (457 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
ERCC3General transcription and DNA repair factor IIH helicase subunit XPB. (782 aa)
XPCDNA repair protein complementing XP-C cells. (962 aa)
CETN2Centrin-2. (204 aa)
POLE4DNA polymerase epsilon subunit 4. (116 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
ERCC4DNA repair endonuclease XPF. (916 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RFC5Replication factor C subunit 5. (341 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (328 aa)
RFC3Replication factor C subunit 3. (356 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
RFC4Replication factor C subunit 4. (376 aa)
CUL4Acullin-4A; Belongs to the cullin family. (637 aa)
ERCC5DNA repair protein complementing XP-G cells isoform X1. (1201 aa)
XPADNA repair protein complementing XP-A cells. (273 aa)
POLE3LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 3. (146 aa)
POLD3DNA polymerase delta subunit 3 isoform X1. (465 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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