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| | FLT1 | Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1298 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LOC103014668 | Transcription factor AP-1; Belongs to the bZIP family. (253 aa) |
| | FLT3 | Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1074 aa) |
| | MKNK1 | MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (459 aa) |
| | LOC103001311 | Transcription factor AP-1-like. (199 aa) |
| | STK3 | Serine/threonine-protein kinase 3. (487 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (187 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | MAP2K5 | Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (528 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1001 aa) |
| | MAP4K3 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (831 aa) |
| | RASGRF1 | Ras-specific guanine nucleotide-releasing factor 1. (1257 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (583 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (499 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | NTF4 | Neurotrophin-4; Belongs to the NGF-beta family. (210 aa) |
| | FLT3LG | Fms-related tyrosine kinase 3 ligand isoform X1. (292 aa) |
| | KDR | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | MAPKAPK3 | MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (436 aa) |
| | CACNA2D2 | Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1075 aa) |
| | ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1. (433 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1343 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X2. (435 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2. (303 aa) |
| | RAP1A | Ras-related protein Rap-1A. (184 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1. (513 aa) |
| | FLT4 | Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1368 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (807 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (271 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (231 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (343 aa) |
| | MRAS | Ras-related protein M-Ras isoform X1. (208 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | RELA | Transcription factor p65 isoform X1. (520 aa) |
| | IGF2 | Insulin-like growth factor II isoform X1. (240 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (112 aa) |
| | HRAS | GTPase HRas isoform X1. (196 aa) |
| | MAPKAPK5 | MAP kinase-activated protein kinase 5 isoform X1. (473 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase 11. (751 aa) |
| | DUSP8 | Dual specificity protein phosphatase 8. (377 aa) |
| | MAPKAPK2 | MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (388 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (171 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (523 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (826 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (486 aa) |
| | LAMTOR3 | Ragulator complex protein LAMTOR3. (124 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1. (901 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | LOC103005053 | Non-specific serine/threonine protein kinase. (551 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (974 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | LOC103012091 | Phospholipase A2. (728 aa) |
| | DUSP5 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (329 aa) |
| | ARRB1 | Beta-arrestin-1 isoform X1. (413 aa) |
| | PLA2G4D | Phospholipase A2. (819 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | VEGFB | Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (396 aa) |
| | MAP4K2 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | RASGRP2 | RAS guanyl-releasing protein 2 isoform X3. (608 aa) |
| | RPS6KA4 | Non-specific serine/threonine protein kinase. (601 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | PDGFA | Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (275 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa) |
| | CACNA2D3 | Voltage-dependent calcium channel subunit alpha-2/delta-3. (1091 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa) |
| | RRAS2 | Ras-related protein R-Ras2. (169 aa) |
| | LOC103018737 | Ras-related protein Rap-1b-like isoform X1. (142 aa) |
| | RPS6KA3 | Non-specific serine/threonine protein kinase. (712 aa) |
| | CDC42 | Cell division control protein 42 homolog isoform X2. (191 aa) |
| | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5. (763 aa) |
| | EPHA2 | Ephrin type-A receptor 2. (975 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (338 aa) |
| | TGFA | Protransforming growth factor alpha. (145 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3 isoform X1. (647 aa) |
| | MAPT | Microtubule-associated protein. (620 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa) |
| | NGFR | Tumor necrosis factor receptor superfamily member 16. (427 aa) |
| | CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa) |
| | MKNK2 | MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (463 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | TEK | Angiopoietin-1 receptor isoform X1. (1125 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | FLNC | filamin-C. (2693 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | CASP3 | Caspase-3; Belongs to the peptidase C14A family. (275 aa) |
| | EFNA1 | ephrin-A1; Belongs to the ephrin family. (205 aa) |
| | EFNA3 | ephrin-A3; Belongs to the ephrin family. (224 aa) |
| | CACNA2D4 | Voltage-dependent calcium channel subunit alpha-2/delta-4. (1108 aa) |
| | EFNA4 | ephrin-A4 isoform X1; Belongs to the ephrin family. (146 aa) |
| | RPS6KA1 | Non-specific serine/threonine protein kinase. (700 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | CACNA2D1 | Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1110 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1338 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (598 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | RASGRF2 | Ras-specific guanine nucleotide-releasing factor 2. (1239 aa) |
| | EREG | Proepiregulin isoform X1. (163 aa) |
| | CACNB3 | Voltage-dependent L-type calcium channel subunit beta-3. (539 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAP4K1 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | AREG | Amphiregulin isoform X1. (254 aa) |
| | RASGRP4 | RAS guanyl-releasing protein 4. (660 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (961 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X1. (611 aa) |
| | ELK1 | ETS domain-containing protein Elk-1. (437 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (153 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (797 aa) |
| | PLA2G4B | Phospholipase A2. (781 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (800 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (256 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | MAPK8IP1 | C-Jun-amino-terminal kinase-interacting protein 1. (720 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit. (228 aa) |
| | MAPK8IP3 | C-Jun-amino-terminal kinase-interacting protein 3 isoform X8. (1380 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha. (293 aa) |
| | CACNA1H | LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2326 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa) |
| | PTPN7 | LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7. (507 aa) |
| | ELK4 | ETS domain-containing protein Elk-4. (432 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (620 aa) |
| | CACNB4 | Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (502 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa) |
| | DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (296 aa) |
| | CRK | Adapter molecule crk isoform X1. (304 aa) |
| | TAOK1 | Serine/threonine-protein kinase TAO1 isoform X1. (1001 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | PDGFC | Platelet-derived growth factor C. (274 aa) |
| | LOC103005459 | Rap guanine nucleotide exchange factor 2. (1407 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa) |
| | PGF | Placenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | TGFB3 | Transforming growth factor beta-3 proprotein. (456 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | CACNG5 | Voltage-dependent calcium channel gamma-5 subunit. (275 aa) |
| | PRKCA | Non-specific serine/threonine protein kinase. (559 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (340 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (368 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | RAC3 | Ras-related C3 botulinum toxin substrate 3. (206 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit. (549 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa) |
| | CACNG3 | Voltage-dependent calcium channel gamma-3 subunit. (315 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (265 aa) |
| | HSPB1 | Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (194 aa) |
| | DAXX | Death domain-associated protein 6. (755 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit isoform X2. (901 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1156 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1298 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (468 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (960 aa) |
| | ANGPT1 | Angiopoietin-1 isoform X1. (498 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | ANGPT2 | Angiopoietin-2 isoform X1. (496 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (453 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (352 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (506 aa) |
| | TAOK3 | Serine/threonine-protein kinase TAO3 isoform X1. (898 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X3. (1219 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1215 aa) |
| | PDGFD | Platelet-derived growth factor D. (352 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa) |
| | RASGRP3 | Ras guanyl-releasing protein 3 isoform X1. (740 aa) |
| | EFNA5 | ephrin-A5 isoform X1; Belongs to the ephrin family. (213 aa) |
| | FLNB | filamin-B isoform X1. (2633 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1272 aa) |
| | PPM1A | Protein phosphatase 1A isoform X1. (382 aa) |
| | LOC103001540 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (411 aa) |
| | ANGPT4 | Angiopoietin-4. (498 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | LOC103020298 | Heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa) |
| | LOC103019729 | Heat shock 70 kDa protein 1B; Belongs to the heat shock protein 70 family. (641 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC103020014 | Heat shock 70 kDa protein 1B; Belongs to the heat shock protein 70 family. (641 aa) |
| | TRAF2 | TNF receptor-associated factor. (412 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) |
| | KRAS | GTPase KRas isoform X3. (227 aa) |
| | PTPRR | Receptor-type tyrosine-protein phosphatase R. (689 aa) |
| | RAP1B | Ras-related protein Rap-1b. (184 aa) |
| | LOC102999798 | Mitogen-activated protein kinase. (203 aa) |
| | MET | Hepatocyte growth factor receptor isoform X1. (1382 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | IL1RAP | Interleukin-1 receptor accessory protein isoform X1. (685 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1362 aa) |
| | JUND | Transcription factor jun-D. (262 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | CDC25B | M-phase inducer phosphatase 2. (574 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1. (263 aa) |
| | DUSP16 | Dual specificity protein phosphatase 16. (495 aa) |
| | CACNB2 | Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa) |
| | HSPA8 | Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (652 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (270 aa) |
| | IL1R1 | Interleukin-1 receptor type 1 isoform X1. (585 aa) |
| | DUSP2 | Dual specificity protein phosphatase 2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (161 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3. (998 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (343 aa) |
| | MAX | LOW QUALITY PROTEIN: protein max. (160 aa) |
| | MAP3K6 | LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 6. (1316 aa) |
| | PPP3R2 | LOW QUALITY PROTEIN: calcineurin subunit B type 2. (170 aa) |
| | VEGFA | Vascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (186 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (963 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4 isoform X1. (1394 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (288 aa) |
| | SRF | Serum response factor. (464 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (331 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12. (253 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (779 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (823 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (282 aa) |
| | FGFR3 | Receptor protein-tyrosine kinase. (843 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2153 aa) |
| | FLNA | filamin-A. (2305 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1602 aa) |
| | TAOK2 | Serine/threonine-protein kinase TAO2 isoform X1. (1234 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | RASA2 | Ras GTPase-activating protein 2 isoform X2. (795 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2331 aa) |
| | CACNA1I | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2076 aa) |
| | PPM1B | Protein phosphatase 1B isoform X1. (477 aa) |
| | NF1 | Neurofibromin. (2821 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1246 aa) |
| | RASA1 | Ras GTPase-activating protein 1. (1041 aa) |
