STRINGSTRING
MTMR6 MTMR6 DGKB DGKB PLCB4 PLCB4 PLCB1 PLCB1 CALML4 CALML4 PIK3C2B PIK3C2B ITPKC ITPKC ITPKB ITPKB PI4K2B PI4K2B IP6K1 IP6K1 IP6K2 IP6K2 IMPAD1 IMPAD1 SACM1L SACM1L PIK3CD PIK3CD PIK3CB PIK3CB MTMR3 MTMR3 PIK3C3 PIK3C3 INPP5F INPP5F INPP5A INPP5A MTMR7 MTMR7 PLCB3 PLCB3 DGKE DGKE PIK3R1 PIK3R1 IPMK IPMK PIP5K1C PIP5K1C PIP4K2B PIP4K2B PIP4P2 PIP4P2 PI4KB PI4KB PIP5K1A PIP5K1A MTM1 MTM1 PTEN PTEN DGKA DGKA PIP4K2C PIP4K2C ITPKA ITPKA PLCD3 PLCD3 PIP4P1 PIP4P1 PLCB2 PLCB2 DGKZ DGKZ OCRL OCRL PRKCG PRKCG DGKQ DGKQ PIP5K1B PIP5K1B IPPK IPPK PLCG2 PLCG2 INPP5B INPP5B DGKK DGKK ITPK1 ITPK1 DGKD DGKD INPP5D INPP5D IMPA1 IMPA1 PRKCA PRKCA SYNJ2 SYNJ2 PRKCB PRKCB CDIPT CDIPT ITPR3 ITPR3 IP6K3 IP6K3 DGKH DGKH PLCE1 PLCE1 PIKFYVE PIKFYVE INPP4B INPP4B PIP4K2A PIP4K2A MTMR8 MTMR8 CALM2 CALM2 MTMR4 MTMR4 MTMR2 MTMR2 CDS2 CDS2 PPIP5K2 PPIP5K2 ITPR1 ITPR1 MTMR14 MTMR14 PLCG1 PLCG1 PLCZ1 PLCZ1 PIK3C2G PIK3C2G ITPR2 ITPR2 DGKG DGKG PIK3R2 PIK3R2 PI4KA PI4KA PPIP5K1 PPIP5K1 IMPA2 IMPA2 INPPL1 INPPL1 PIK3CA PIK3CA INPP5E INPP5E INPP4A INPP4A LOC103008077 LOC103008077 INPP1 INPP1 LOC103020340 LOC103020340 PIK3C2A PIK3C2A DGKI DGKI MTMR1 MTMR1 SYNJ1 SYNJ1 PLCD4 PLCD4 CDS1 CDS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTMR6Myotubularin-related protein 6. (621 aa)
DGKBDiacylglycerol kinase. (803 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
CALML4Calmodulin-like protein 4. (153 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1; Belongs to the PI3/PI4-kinase family. (1634 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (618 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (940 aa)
PI4K2BLOW QUALITY PROTEIN: phosphatidylinositol 4-kinase type 2-beta. (494 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
IMPAD1Inositol monophosphatase 3. (365 aa)
SACM1LLOW QUALITY PROTEIN: phosphatidylinositide phosphatase SAC1. (587 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1042 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1220 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
INPP5FPhosphatidylinositide phosphatase SAC2 isoform X1. (1038 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase isoform X3. (412 aa)
MTMR7Myotubularin-related protein 7 isoform X1. (660 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
DGKEDiacylglycerol kinase. (564 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (419 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1. (661 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PI4KBPhosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family. (816 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (562 aa)
MTM1LOW QUALITY PROTEIN: myotubularin. (609 aa)
PTENPhosphatase and tensin homolog. (612 aa)
DGKADiacylglycerol kinase. (734 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (421 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (289 aa)
PLCD3Phosphoinositide phospholipase C. (741 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
DGKZDiacylglycerol kinase. (1121 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1. (882 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
DGKQDiacylglycerol kinase. (938 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (554 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
INPP5BLOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase. (995 aa)
DGKKDiacylglycerol kinase. (1222 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (332 aa)
DGKDDiacylglycerol kinase. (1165 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1301 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
SYNJ2Synaptojanin-2. (1440 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (389 aa)
DGKHDiacylglycerol kinase. (1080 aa)
PLCE1Phosphoinositide phospholipase C. (1973 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2109 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase isoform X1. (939 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha. (406 aa)
MTMR8Myotubularin-related protein 8. (553 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1210 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1302 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
MTMR14Myotubularin-related protein 14 isoform X1. (664 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
PLCZ1Phosphoinositide phospholipase C. (669 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1454 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
DGKGDiacylglycerol kinase. (791 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (700 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2044 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1534 aa)
IMPA2Inositol-1-monophosphatase. (287 aa)
INPPL1LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1174 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (745 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (990 aa)
LOC103008077Phosphatidylinositol 3-kinase regulatory subunit gamma. (484 aa)
INPP1Inositol polyphosphate 1-phosphatase. (387 aa)
LOC103020340CDP-diacylglycerol--inositol 3-phosphatidyltransferase-like; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (148 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1689 aa)
DGKIDiacylglycerol kinase. (731 aa)
MTMR1Myotubularin-related protein 1 isoform X4. (586 aa)
SYNJ1Synaptojanin-1 isoform X1. (1611 aa)
PLCD4Phosphoinositide phospholipase C. (801 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (374 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.