STRINGSTRING
ATP6V0B ATP6V0B PPT1 PPT1 LAPTM4B LAPTM4B SCARB2 SCARB2 GGA1 GGA1 GNPTAB GNPTAB CD68 CD68 AP3M1 AP3M1 AP1S3 AP1S3 SLC17A5 SLC17A5 PSAP PSAP CTSH CTSH ENTPD4 ENTPD4 CTSC CTSC HYAL1 HYAL1 ATP6V1H ATP6V1H HYAL3 HYAL3 HYAL2 HYAL2 ACP5 ACP5 AP1M2 AP1M2 MCOLN1 MCOLN1 AP4B1 AP4B1 SORT1 SORT1 CLTB CLTB AP4E1 AP4E1 LAPTM5 LAPTM5 AP1B1 AP1B1 CTSF CTSF CTSW CTSW TCIRG1 TCIRG1 FUCA2 FUCA2 DNASE2 DNASE2 MAN2B1 MAN2B1 MFSD8 MFSD8 PSAPL1 PSAPL1 GALNS GALNS TPP1 TPP1 MANBA MANBA DNASE2B DNASE2B SMPD1 SMPD1 ASAH1 ASAH1 FUCA1 FUCA1 ARSB ARSB AP3B1 AP3B1 HEXB HEXB ATP6V0D2 ATP6V0D2 AP3D1 AP3D1 LOC103003105 LOC103003105 LOC103009986 LOC103009986 ATP6V0A4 ATP6V0A4 HYAL4 HYAL4 SPAM1 SPAM1 CTNS CTNS LOC103019480 LOC103019480 CTSK CTSK CTSS CTSS GBA GBA LIPA LIPA CD63 CD63 NAPSA NAPSA AP1G2 AP1G2 LOC103010195 LOC103010195 LOC103009512 LOC103009512 AP4S1 AP4S1 ACP2 ACP2 GLA GLA NAGPA NAGPA ATP6V0C ATP6V0C GNPTG GNPTG AP3M2 AP3M2 AP1S2 AP1S2 LAPTM4A LAPTM4A AP1M1 AP1M1 CTSO CTSO LGMN LGMN NPC2 NPC2 CTSA CTSA ATP6AP1 ATP6AP1 ARSG ARSG GGA3 GGA3 GAA GAA SGSH SGSH CLN5 CLN5 GUSB GUSB AP1S1 AP1S1 AP4M1 AP4M1 LITAF LITAF GM2A GM2A GALC GALC AGA AGA NAGA NAGA ARSA ARSA ABCB9 ABCB9 ATP6V0A2 ATP6V0A2 CLTC CLTC CD164 CD164 GLB1 GLB1 SUMF1 SUMF1 CTSB CTSB NEU1 NEU1 LOC103004775 LOC103004775 AP3B2 AP3B2 LAMP3 LAMP3 M6PR M6PR LAMP1 LAMP1 CLTA CLTA NPC1 NPC1 HEXA HEXA PLA2G15 PLA2G15 GGA2 GGA2 AP1G1 AP1G1 ATP6V0D1 ATP6V0D1 PPT2 PPT2 CTSD CTSD LOC103011932 LOC103011932 HGSNAT HGSNAT IDS IDS SLC11A2 SLC11A2 IDUA IDUA ABCA2 ABCA2 CTSZ CTSZ IGF2R IGF2R CLN3 CLN3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
LAPTM4BLysosomal-associated transmembrane protein 4B. (207 aa)
SCARB2Lysosome membrane protein 2 isoform X1; Belongs to the CD36 family. (491 aa)
GGA1ADP-ribosylation factor-binding protein GGA1 isoform X1. (636 aa)
GNPTABN-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1. (1258 aa)
CD68Macrosialin. (418 aa)
AP3M1AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (418 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (225 aa)
SLC17A5Sialin. (573 aa)
PSAPProsaposin isoform X1. (528 aa)
CTSHPro-cathepsin H isoform X1; Belongs to the peptidase C1 family. (297 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (616 aa)
CTSCDipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (547 aa)
HYAL1Hyaluronidase. (467 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
HYAL3Hyaluronidase. (517 aa)
HYAL2Hyaluronidase. (476 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (349 aa)
AP1M2AP-1 complex subunit mu-2 isoform X1; Belongs to the adaptor complexes medium subunit family. (425 aa)
MCOLN1Mucolipin-1. (520 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
SORT1Sortilin. (694 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (175 aa)
AP4E1AP-4 complex subunit epsilon-1 isoform X1. (1201 aa)
LAPTM5Lysosomal-associated transmembrane protein 5. (264 aa)
AP1B1AP complex subunit beta. (950 aa)
CTSFCathepsin F; Belongs to the peptidase C1 family. (425 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (376 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (745 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (462 aa)
DNASE2Deoxyribonuclease-2-alpha. (351 aa)
MAN2B1Alpha-mannosidase. (1008 aa)
MFSD8Major facilitator superfamily domain-containing protein 8 isoform X1. (519 aa)
PSAPL1LOW QUALITY PROTEIN: proactivator polypeptide-like 1. (533 aa)
GALNSN-acetylgalactosamine-6-sulfatase. (522 aa)
TPP1Tripeptidyl-peptidase 1. (572 aa)
MANBABeta-mannosidase. (1010 aa)
DNASE2BDeoxyribonuclease-2-beta. (335 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
ASAH1Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] (395 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (477 aa)
ARSBArylsulfatase B. (452 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1086 aa)
HEXBBeta-hexosaminidase. (546 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1140 aa)
LOC103003105Cathepsin L1 isoform X1; Belongs to the peptidase C1 family. (333 aa)
LOC103009986Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (879 aa)
HYAL4Hyaluronidase. (481 aa)
SPAM1Hyaluronidase. (554 aa)
CTNSCystinosin isoform X1. (389 aa)
LOC103019480V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (340 aa)
GBAGlucosylceramidase. (536 aa)
LIPALysosomal acid lipase/cholesteryl ester hydrolase isoform X1. (482 aa)
CD63Tetraspanin. (237 aa)
NAPSAnapsin-A isoform X1; Belongs to the peptidase A1 family. (436 aa)
AP1G2AP-1 complex subunit gamma. (787 aa)
LOC103010195Cathepsin G-like; Belongs to the peptidase S1 family. (250 aa)
LOC103009512Cathepsin G; Belongs to the peptidase S1 family. (250 aa)
AP4S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
ACP2Lysosomal acid phosphatase isoform X1; Belongs to the histidine acid phosphatase family. (521 aa)
GLAAlpha-galactosidase. (425 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase isoform X1. (545 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
GNPTGN-acetylglucosamine-1-phosphotransferase subunit gamma. (306 aa)
AP3M2AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (418 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (171 aa)
LAPTM4ALysosomal-associated transmembrane protein 4A. (233 aa)
AP1M1AP-1 complex subunit mu-1 isoform X2; Belongs to the adaptor complexes medium subunit family. (423 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (299 aa)
LGMNLegumain. (433 aa)
NPC2NPC intracellular cholesterol transporter 2. (149 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (495 aa)
ATP6AP1V-type proton ATPase subunit S1. (468 aa)
ARSGArylsulfatase G isoform X1. (525 aa)
GGA3ADP-ribosylation factor-binding protein GGA3 isoform X1. (722 aa)
GAALysosomal alpha-glucosidase isoform X1; Belongs to the glycosyl hydrolase 31 family. (940 aa)
SGSHN-sulphoglucosamine sulphohydrolase isoform X1. (517 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5. (273 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (652 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
AP4M1AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (460 aa)
LITAFLipopolysaccharide-induced tumor necrosis factor-alpha factor. (161 aa)
GM2AGanglioside GM2 activator. (196 aa)
GALCGalactocerebrosidase. (685 aa)
AGAN(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase. (346 aa)
NAGAAlpha-galactosidase. (411 aa)
ARSAArylsulfatase A isoform X1. (533 aa)
ABCB9ATP-binding cassette sub-family B member 9. (766 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
CD164Sialomucin core protein 24. (199 aa)
GLB1Beta-galactosidase. (660 aa)
SUMF1Formylglycine-generating enzyme isoform X1. (424 aa)
CTSBCathepsin B isoform X1; Belongs to the peptidase C1 family. (335 aa)
NEU1Sialidase-1 isoform X1. (416 aa)
LOC103004775AP-3 complex subunit sigma-2. (193 aa)
AP3B2AP-3 complex subunit beta. (1118 aa)
LAMP3Lysosome-associated membrane glycoprotein 3 isoform X1. (423 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (278 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (438 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (255 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
HEXABeta-hexosaminidase. (529 aa)
PLA2G15Group XV phospholipase A2 isoform X1. (435 aa)
GGA2ADP-ribosylation factor-binding protein GGA2. (621 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
PPT2LOW QUALITY PROTEIN: lysosomal thioesterase PPT2. (317 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (482 aa)
LOC103011932alpha-N-acetylglucosaminidase isoform X1. (754 aa)
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase isoform X1. (581 aa)
IDSIduronate 2-sulfatase. (487 aa)
SLC11A2Natural resistance-associated macrophage protein 2 isoform X1. (581 aa)
IDUALOW QUALITY PROTEIN: alpha-L-iduronidase. (705 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2133 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (331 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2426 aa)
CLN3Battenin. (446 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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