Your Input: | |||||
CCNE1 | LOW QUALITY PROTEIN: G1/S-specific cyclin-E1; Belongs to the cyclin family. (416 aa) | ||||
CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (405 aa) | ||||
LIN37 | Protein lin-37 homolog isoform X1. (246 aa) | ||||
RHEB | GTP-binding protein Rheb. (179 aa) | ||||
CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
CALML4 | Calmodulin-like protein 4. (153 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) | ||||
VDAC2 | Voltage-dependent anion-selective channel protein 2 isoform X3. (309 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (528 aa) | ||||
HIPK4 | Homeodomain-interacting protein kinase 4. (612 aa) | ||||
ZFP36L2 | mRNA decay activator protein ZFP36L2. (376 aa) | ||||
RBL2 | Retinoblastoma-like protein 2. (1160 aa) | ||||
MCU | Calcium uniporter protein, mitochondrial. (348 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (583 aa) | ||||
LIN54 | Protein lin-54 homolog isoform X1. (748 aa) | ||||
SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa) | ||||
CDC25A | M-phase inducer phosphatase 1 isoform X1. (524 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2. (303 aa) | ||||
HIPK1 | Homeodomain-interacting protein kinase 1. (1211 aa) | ||||
SQSTM1 | Sequestosome-1. (440 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1042 aa) | ||||
EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa) | ||||
CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) | ||||
FOXM1 | Forkhead box protein M1 isoform X2. (758 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) | ||||
MRAS | Ras-related protein M-Ras isoform X1. (208 aa) | ||||
TRPM7 | Transient receptor potential cation channel subfamily M member 7 isoform X1. (1867 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) | ||||
CHEK2 | Serine/threonine-protein kinase Chk2. (544 aa) | ||||
CCND1 | G1/S-specific cyclin-D1 isoform X1; Belongs to the cyclin family. (214 aa) | ||||
RELA | Transcription factor p65 isoform X1. (520 aa) | ||||
HRAS | GTPase HRas isoform X1. (196 aa) | ||||
FBXW11 | F-box/WD repeat-containing protein 11 isoform X1. (563 aa) | ||||
PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (363 aa) | ||||
MAPKAPK2 | MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (388 aa) | ||||
GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (171 aa) | ||||
VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) | ||||
CCNA2 | cyclin-A2; Belongs to the cyclin family. (435 aa) | ||||
SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) | ||||
NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1. (901 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (974 aa) | ||||
LOC103007740 | H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (349 aa) | ||||
SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa) | ||||
MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa) | ||||
RRAS2 | Ras-related protein R-Ras2. (169 aa) | ||||
CCNB1 | G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa) | ||||
GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) | ||||
CDKN2B | Cyclin-dependent kinase 4 inhibitor B isoform X1. (131 aa) | ||||
LOC103012968 | Cyclin-dependent kinase inhibitor 2A. (109 aa) | ||||
HIPK2 | Homeodomain-interacting protein kinase 2 isoform X1. (1207 aa) | ||||
SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (259 aa) | ||||
SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (283 aa) | ||||
PTEN | Phosphatase and tensin homolog. (612 aa) | ||||
CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) | ||||
CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (303 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) | ||||
E2F5 | Transcription factor E2F5. (333 aa) | ||||
NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (901 aa) | ||||
HIPK3 | Homeodomain-interacting protein kinase 3 isoform X1. (1214 aa) | ||||
VDAC3 | Voltage-dependent anion-selective channel protein 3 isoform X1. (282 aa) | ||||
NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa) | ||||
RBBP4 | Histone-binding protein RBBP4. (425 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa) | ||||
ETS1 | Protein C-ets-1 isoform X1. (485 aa) | ||||
CHEK1 | Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa) | ||||
IL6 | Interleukin-6. (208 aa) | ||||
PPID | Peptidyl-prolyl cis-trans isomerase D. (370 aa) | ||||
ZFP36L1 | mRNA decay activator protein ZFP36L1. (323 aa) | ||||
LIN52 | Protein lin-52 homolog isoform X1. (116 aa) | ||||
TGFB3 | Transforming growth factor beta-3 proprotein. (456 aa) | ||||
MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (368 aa) | ||||
MAPK3 | Mitogen-activated protein kinase 3. (265 aa) | ||||
SERPINE1 | Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa) | ||||
RB1 | Retinoblastoma-associated protein. (816 aa) | ||||
ITPR3 | LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa) | ||||
BTRC | F-box/WD repeat-containing protein 1A isoform X1. (611 aa) | ||||
IGFBP3 | Insulin-like growth factor-binding protein 3. (146 aa) | ||||
ATR | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2645 aa) | ||||
RAD50 | DNA repair protein RAD50 isoform X1. (1312 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) | ||||
LOC103012727 | Voltage-dependent anion-selective channel protein 3-like. (264 aa) | ||||
PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) | ||||
MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa) | ||||
CALM2 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) | ||||
TRAF3IP2 | Adapter protein CIKS isoform X1. (565 aa) | ||||
PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) | ||||
TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa) | ||||
RAD1 | Cell cycle checkpoint protein RAD1 isoform X1. (279 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa) | ||||
GATA4 | Transcription factor GATA-4. (229 aa) | ||||
RBL1 | Retinoblastoma-like protein 1. (1068 aa) | ||||
MYBL2 | Myb-related protein B. (803 aa) | ||||
E2F1 | Transcription factor E2F1. (361 aa) | ||||
GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) | ||||
FOXO1 | Forkhead box protein O1. (518 aa) | ||||
CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) | ||||
TSC1 | Hamartin. (1155 aa) | ||||
KRAS | GTPase KRas isoform X3. (227 aa) | ||||
LOC102999798 | Mitogen-activated protein kinase. (203 aa) | ||||
MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa) | ||||
RASSF5 | Ras association domain-containing protein 5 isoform X1. (421 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (700 aa) | ||||
CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
MAPK1 | Mitogen-activated protein kinase 1. (263 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) | ||||
E2F3 | Transcription factor E2F3. (340 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (270 aa) | ||||
LOC103019749 | Calpain-2 catalytic subunit-like; Belongs to the peptidase C2 family. (445 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3. (998 aa) | ||||
CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) | ||||
E2F4 | Transcription factor E2F4 isoform X1. (421 aa) | ||||
CAPN2 | LOW QUALITY PROTEIN: calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (585 aa) | ||||
PPP3R2 | LOW QUALITY PROTEIN: calcineurin subunit B type 2. (170 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
LOC103008230 | BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family. (388 aa) | ||||
LIN9 | Protein lin-9 homolog. (490 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (288 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa) | ||||
LOC103008077 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (484 aa) | ||||
CAPN1 | Calpain-1 catalytic subunit isoform X2; Belongs to the peptidase C2 family. (959 aa) | ||||
E2F2 | Transcription factor E2F2. (414 aa) | ||||
TSC2 | LOW QUALITY PROTEIN: tuberin. (1815 aa) | ||||
CCNB3 | LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1428 aa) | ||||
NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X3. (818 aa) | ||||
RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (413 aa) | ||||
FOXO3 | LOW QUALITY PROTEIN: forkhead box protein O3. (467 aa) |