STRINGSTRING
PLCB4 PLCB4 PLCB1 PLCB1 GRIA1 GRIA1 PRKG2 PRKG2 CALML4 CALML4 GNB1 GNB1 PER1 PER1 GNAO1 GNAO1 ADCY7 ADCY7 GNG8 GNG8 GRIN2D GRIN2D GNAI2 GNAI2 GNAI3 GNAI3 PER3 PER3 GNB3 GNB3 GNG4 GNG4 RYR2 RYR2 CUNH1orf226 CUNH1orf226 KCNJ9 KCNJ9 ADCY10 ADCY10 PRKACB PRKACB PLCB3 PLCB3 RASD1 RASD1 CACNA1D CACNA1D ADCY5 ADCY5 CACNA1G CACNA1G GNG7 GNG7 ADCY6 ADCY6 ADCY4 ADCY4 RYR3 RYR3 PLCB2 PLCB2 RPS6KA5 RPS6KA5 PRKCG PRKCG ADCY9 ADCY9 GNG13 GNG13 PRKACA PRKACA CACNA1H CACNA1H LOC103018216 LOC103018216 GUCY1A2 GUCY1A2 GRIN1 GRIN1 PRKG1 PRKG1 KCNJ3 KCNJ3 KCNJ5 KCNJ5 KCNJ6 KCNJ6 GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 GRIA2 GRIA2 FOS FOS PER2 PER2 LOC103004158 LOC103004158 PRKCA PRKCA GRIN2C GRIN2C PRKCB PRKCB MAPK3 MAPK3 GNB2 GNB2 ITPR3 ITPR3 GNAI1 GNAI1 ADCY1 ADCY1 GRIN2A GRIN2A CAMK2A CAMK2A ADCY8 ADCY8 CALM2 CALM2 ADCY3 ADCY3 ADCYAP1 ADCYAP1 ADCY2 ADCY2 ITPR1 ITPR1 GNG2 GNG2 GNB5 GNB5 GNB4 GNB4 GNGT1 GNGT1 GNG11 GNG11 GRIN2B GRIN2B MAPK1 MAPK1 LOC103012311 LOC103012311 CREB1 CREB1 MTNR1B MTNR1B ADCYAP1R1 ADCYAP1R1 CACNA1C CACNA1C RYR1 RYR1 GNAS GNAS CAMK2B CAMK2B CACNA1I CACNA1I NOS1 NOS1 GRIA4 GRIA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
CALML4Calmodulin-like protein 4. (153 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (296 aa)
PER1Period circadian protein homolog 1 isoform X1. (1267 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (302 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (810 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PER3Period circadian protein homolog 3 isoform X1. (1145 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
RYR2Ryanodine receptor 2 isoform X1. (4884 aa)
CUNH1orf226Uncharacterized protein C1orf226 homolog isoform X1. (689 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3 isoform X1. (470 aa)
ADCY10Adenylate cyclase type 10. (1614 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
RASD1Dexamethasone-induced Ras-related protein 1. (189 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1220 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
RYR3LOW QUALITY PROTEIN: ryanodine receptor 3. (4927 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
CACNA1HLOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2326 aa)
LOC103018216Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (329 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (502 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (550 aa)
GRIA2Glutamate receptor 2 isoform X9. (940 aa)
FOSProto-oncogene c-Fos. (380 aa)
PER2Period circadian protein homolog 2. (1251 aa)
LOC103004158Neuroendocrine secretory protein 55-like. (244 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (948 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ADCY1Adenylate cyclase type 1 isoform X1. (907 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (972 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (301 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1491 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
LOC103012311Adenylate cyclase type 10-like. (1539 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
MTNR1BLOW QUALITY PROTEIN: melatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (535 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (513 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
RYR1Ryanodine receptor 1. (4841 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (501 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2076 aa)
NOS1LOW QUALITY PROTEIN: nitric oxide synthase, brain. (1590 aa)
GRIA4Glutamate receptor 4 isoform X1. (632 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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