95 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HTR1F	5-hydroxytryptamine receptor 1F. (365 aa)
	APP	Amyloid-beta precursor protein isoform X1. (735 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (296 aa)
	ALOX15B	LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase B. (678 aa)
	ALOX15	LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
	PTGS2	Prostaglandin G/H synthase 2. (604 aa)
	GNAO1	Guanine nucleotide-binding protein G(O) subunit alpha. (302 aa)
	HTR1B	5-hydroxytryptamine receptor 1B. (390 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
	GNAI2	Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
	NRAS	GTPase NRas. (189 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	HRAS	GTPase HRas isoform X1. (196 aa)
	GABRB2	Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
	KCNJ9	G protein-activated inward rectifier potassium channel 3 isoform X1. (470 aa)
	HTR3A	5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
	HTR3B	5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (437 aa)
	SLC18A2	Synaptic vesicular amine transporter. (521 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	PLA2G4F	Phospholipase A2. (849 aa)
	LOC103012091	Phospholipase A2. (728 aa)
	PLA2G4D	Phospholipase A2. (819 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
	HTR6	5-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	TPH1	Tryptophan 5-hydroxylase 1. (444 aa)
	HTR1D	5-hydroxytryptamine receptor 1D. (404 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
	HTR1A	5-hydroxytryptamine receptor 1A. (422 aa)
	ALOX5	Arachidonate 5-lipoxygenase isoform X1. (674 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	KCND2	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
	CASP3	Caspase-3; Belongs to the peptidase C14A family. (275 aa)
	PTGS1	Prostaglandin G/H synthase 1 isoform X1. (622 aa)
	DDC	aromatic-L-amino-acid decarboxylase. (487 aa)
	GABRB3	Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3 isoform X1. (936 aa)
	MAOB	Amine oxidase. (520 aa)
	ARAF	Serine/threonine-protein kinase A-Raf isoform X1. (611 aa)
	MAOA	Amine oxidase. (527 aa)
	PLA2G4B	Phospholipase A2. (781 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
	GABRB1	Gamma-aminobutyric acid receptor subunit beta-1 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
	HTR2C	5-hydroxytryptamine receptor 2C. (457 aa)
	LOC103018216	Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4. (419 aa)
	KCNJ6	G protein-activated inward rectifier potassium channel 2. (502 aa)
	SLC18A1	Chromaffin granule amine transporter isoform X1. (523 aa)
	HTR2B	5-hydroxytryptamine receptor 2B isoform X1. (537 aa)
	LOC103004158	Neuroendocrine secretory protein 55-like. (244 aa)
	PRKCA	Non-specific serine/threonine protein kinase. (559 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
	MAPK3	Mitogen-activated protein kinase 3. (265 aa)
	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (470 aa)
	ITPR3	LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
	LOC103017669	Cytochrome P450 2C23-like; Belongs to the cytochrome P450 family. (504 aa)
	HTR7	5-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	TRPC1	Short transient receptor potential channel 1 isoform X3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
	LOC103007607	Cytochrome P450 2D14 isoform X1; Belongs to the cytochrome P450 family. (499 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	KCNN2	LOW QUALITY PROTEIN: small conductance calcium-activated potassium channel protein 2. (856 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	KRAS	GTPase KRas isoform X3. (227 aa)
	TPH2	Tryptophan 5-hydroxylase 2. (491 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
	GNB5	Guanine nucleotide-binding protein subunit beta-5 isoform X1. (301 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	MAPK1	Mitogen-activated protein kinase 1. (263 aa)
	HTR4	5-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2153 aa)
	SLC6A4	Sodium-dependent serotonin transporter isoform X1. (507 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S-type. (683 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNAI1	A0A383ZKM3	A0A384AIK2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-1.	0.944
ADCY5	GNAI2	A0A383ZKM3	A0A383Z0V6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-2.	0.948
ADCY5	GNAI3	A0A383ZKM3	A0A383Z373	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.944
ADCY5	GNAO1	A0A383ZKM3	A0A383YXN4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(O) subunit alpha.	0.939
ADCY5	GNAS	A0A383ZKM3	A0A452CJB3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1.	0.999
ADCY5	GNB1	A0A383ZKM3	A0A383YTW1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.941
ADCY5	GNB2	A0A383ZKM3	A0A384AH64	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.950
ADCY5	GNB3	A0A383ZKM3	A0A383Z533	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1.	0.950
ADCY5	GNB4	A0A383ZKM3	A0A384B6V0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-4.	0.941
ADCY5	GNB5	A0A383ZKM3	A0A384B6Q2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-5 isoform X1.	0.950
ADCY5	GNG11	A0A383ZKM3	A0A384B815	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.948
ADCY5	GNG13	A0A383ZKM3	A0A384A3B2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.947
ADCY5	GNG2	A0A383ZKM3	A0A384B024	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.913
ADCY5	GNG4	A0A383ZKM3	A0A383Z6V3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.939
ADCY5	GNG7	A0A383ZKM3	A0A383ZNG2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.940
ADCY5	GNG8	A0A383ZKM3	A0A383YZK6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.950
ADCY5	GNGT1	A0A383ZKM3	A0A384B7Y7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.949
ADCY5	LOC103004158	A0A383ZKM3	A0A384ADB9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55-like.	0.901
ADCY5	PLCB1	A0A383ZKM3	A0A383YRE2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.541
ADCY5	PLCB4	A0A383ZKM3	A0A383YR77	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.534