56 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
	GRIA1	Glutamate receptor 1 isoform X1. (906 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	IGF1	Insulin-like growth factor I isoform X1. (187 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	GNAO1	Guanine nucleotide-binding protein G(O) subunit alpha. (302 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	GNAI2	Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
	NRAS	GTPase NRas. (189 aa)
	MAP2K2	Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	HRAS	GTPase HRas isoform X1. (196 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	PPP2R1B	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X4. (666 aa)
	PLA2G4F	Phospholipase A2. (849 aa)
	LOC103012091	Phospholipase A2. (728 aa)
	PLA2G4D	Phospholipase A2. (819 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (244 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	PPP1R17	Protein phosphatase 1 regulatory subunit 17 isoform X1. (152 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	GNA11	Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
	ARAF	Serine/threonine-protein kinase A-Raf isoform X1. (611 aa)
	PLA2G4B	Phospholipase A2. (781 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC103018216	Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
	GUCY1A2	Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (329 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	GRID2	Glutamate receptor ionotropic, delta-2. (1007 aa)
	GUCY1A1	Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
	GUCY1B1	Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (550 aa)
	GRIA2	Glutamate receptor 2 isoform X9. (940 aa)
	CRH	Corticoliberin. (193 aa)
	LOC103004158	Neuroendocrine secretory protein 55-like. (244 aa)
	GNA13	Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
	PRKCA	Non-specific serine/threonine protein kinase. (559 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
	MAPK3	Mitogen-activated protein kinase 3. (265 aa)
	ITPR3	LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
	KRAS	GTPase KRas isoform X3. (227 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
	MAPK1	Mitogen-activated protein kinase 1. (263 aa)
	GNAZ	Guanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
	GNA12	Guanine nucleotide-binding protein subunit alpha-12. (253 aa)
	CRHR1	Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (432 aa)
	RYR1	Ryanodine receptor 1. (4841 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2185 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
	NOS1	LOW QUALITY PROTEIN: nitric oxide synthase, brain. (1590 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1246 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARAF	HRAS	A0A383ZYX6	A0A383Z7Q9	Serine/threonine-protein kinase A-Raf isoform X1.	GTPase HRas isoform X1.	0.969
ARAF	KRAS	A0A383ZYX6	A0A384B5J9	Serine/threonine-protein kinase A-Raf isoform X1.	GTPase KRas isoform X3.	0.976
ARAF	LYN	A0A383ZYX6	A0A383Z0K5	Serine/threonine-protein kinase A-Raf isoform X1.	Tyrosine-protein kinase.	0.491
ARAF	MAP2K1	A0A383ZYX6	A0A383YTE9	Serine/threonine-protein kinase A-Raf isoform X1.	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.971
ARAF	MAP2K2	A0A383ZYX6	A0A383Z2X0	Serine/threonine-protein kinase A-Raf isoform X1.	Dual specificity mitogen-activated protein kinase kinase 2.	0.972
ARAF	MAPK1	A0A383ZYX6	A0A384B9K1	Serine/threonine-protein kinase A-Raf isoform X1.	Mitogen-activated protein kinase 1.	0.577
ARAF	MAPK3	A0A383ZYX6	A0A384AGR0	Serine/threonine-protein kinase A-Raf isoform X1.	Mitogen-activated protein kinase 3.	0.577
ARAF	NRAS	A0A383ZYX6	A0A383Z2W3	Serine/threonine-protein kinase A-Raf isoform X1.	GTPase NRas.	0.976
ARAF	PPP2R1A	A0A383ZYX6	A0A383ZXS2	Serine/threonine-protein kinase A-Raf isoform X1.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.	0.401
ARAF	PRKCA	A0A383ZYX6	A0A384AE52	Serine/threonine-protein kinase A-Raf isoform X1.	Non-specific serine/threonine protein kinase.	0.918
ARAF	PRKCB	A0A383ZYX6	A0A384AGA0	Serine/threonine-protein kinase A-Raf isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.911
ARAF	PRKCG	A0A383ZYX6	A0A384A2A1	Serine/threonine-protein kinase A-Raf isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.911
ARAF	RAF1	A0A383ZYX6	A0A384AYZ0	Serine/threonine-protein kinase A-Raf isoform X1.	RAF proto-oncogene serine/threonine-protein kinase isoform X1.	0.912
CACNA1A	GNAI1	A0A452CGY1	A0A384AIK2	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Guanine nucleotide-binding protein G(I) subunit alpha-1.	0.664
CACNA1A	GNAI2	A0A452CGY1	A0A383Z0V6	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Guanine nucleotide-binding protein G(I) subunit alpha-2.	0.664
CACNA1A	GNAI3	A0A452CGY1	A0A383Z373	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.664
CACNA1A	GNAO1	A0A452CGY1	A0A383YXN4	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Guanine nucleotide-binding protein G(O) subunit alpha.	0.699
CACNA1A	GRIA1	A0A452CGY1	A0A383YRR5	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Glutamate receptor 1 isoform X1.	0.528
CACNA1A	PRKCA	A0A452CGY1	A0A384AE52	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Non-specific serine/threonine protein kinase.	0.910
CACNA1A	PRKCB	A0A452CGY1	A0A384AGA0	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.910