STRINGSTRING
LOC103014668 LOC103014668 LOC103001311 LOC103001311 PLCB4 PLCB4 PLCB1 PLCB1 CALML4 CALML4 MAP2K1 MAP2K1 PLD2 PLD2 SOS1 SOS1 MMP2 MMP2 ADCY7 ADCY7 LOC103020549 LOC103020549 MAP2K7 MAP2K7 NRAS NRAS MAP2K2 MAP2K2 HRAS HRAS EGR1 EGR1 PRKACB PRKACB PLA2G4F PLA2G4F LOC103012091 LOC103012091 PLA2G4D PLA2G4D MAP2K3 MAP2K3 PLCB3 PLCB3 PRKCD PRKCD CACNA1D CACNA1D CDC42 CDC42 MAP2K4 MAP2K4 PLA2G4A PLA2G4A ADCY5 ADCY5 MAP3K3 MAP3K3 GNA11 GNA11 MAPK10 MAPK10 MAPK8 MAPK8 ADCY6 ADCY6 ELK1 ELK1 PLA2G4B PLA2G4B ADCY4 ADCY4 MMP14 MMP14 PLCB2 PLCB2 LOC102997225 LOC102997225 LOC103010492 LOC103010492 ADCY9 ADCY9 PRKACA PRKACA LOC103018216 LOC103018216 CACNA1F CACNA1F MAP3K2 MAP3K2 LOC103004158 LOC103004158 PRKCA PRKCA MAP2K6 MAP2K6 GRB2 GRB2 PRKCB PRKCB MAPK3 MAPK3 ITPR3 ITPR3 ADCY1 ADCY1 EGFR EGFR CAMK2A CAMK2A ADCY8 ADCY8 ATF4 ATF4 CALM2 CALM2 ADCY3 ADCY3 ADCY2 ADCY2 RAF1 RAF1 ITPR1 ITPR1 SOS2 SOS2 GNRH1 GNRH1 SRC SRC GNRHR GNRHR HBEGF HBEGF KRAS KRAS LOC102999798 LOC102999798 ITPR2 ITPR2 MAP3K1 MAP3K1 GNRH2 GNRH2 CGA CGA MAPK1 MAPK1 PLD1 PLD1 MAPK14 MAPK14 CACNA1S CACNA1S MAPK13 MAPK13 MAPK7 MAPK7 CACNA1C CACNA1C GNAS GNAS MAP3K4 MAP3K4 CAMK2B CAMK2B PTK2B PTK2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103014668Transcription factor AP-1; Belongs to the bZIP family. (253 aa)
LOC103001311Transcription factor AP-1-like. (199 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
CALML4Calmodulin-like protein 4. (153 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLD2Phospholipase. (933 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1001 aa)
MMP272 kDa type IV collagenase. (584 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
LOC103020549Lutropin subunit beta. (253 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X2. (435 aa)
NRASGTPase NRas. (189 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
HRASGTPase HRas isoform X1. (196 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (539 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
PLA2G4FPhospholipase A2. (849 aa)
LOC103012091Phospholipase A2. (728 aa)
PLA2G4DPhospholipase A2. (819 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (338 aa)
PLA2G4APhospholipase A2. (749 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3 isoform X1. (647 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1220 aa)
ELK1ETS domain-containing protein Elk-1. (437 aa)
PLA2G4BPhospholipase A2. (781 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
LOC102997225Follitropin subunit beta. (129 aa)
LOC103010492Follitropin subunit beta-like. (171 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC103018216Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (620 aa)
LOC103004158Neuroendocrine secretory protein 55-like. (244 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (368 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
ADCY1Adenylate cyclase type 1 isoform X1. (907 aa)
EGFRReceptor protein-tyrosine kinase. (1156 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (972 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1272 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (95 aa)
SRCTyrosine-protein kinase. (557 aa)
GNRHRGonadotropin-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (328 aa)
HBEGFProheparin-binding EGF-like growth factor isoform X1. (262 aa)
KRASGTPase KRas isoform X3. (227 aa)
LOC102999798Mitogen-activated protein kinase. (203 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1362 aa)
GNRH2Progonadoliberin-2. (125 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
PLD1Phospholipase. (1075 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
MAPK13Mitogen-activated protein kinase. (288 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (779 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2273 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1602 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (501 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1017 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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