STRINGSTRING
PLCB4 PLCB4 PLCB1 PLCB1 KITLG KITLG CALML4 CALML4 MAP2K1 MAP2K1 DVL2 DVL2 GNAO1 GNAO1 ADCY7 ADCY7 TYR TYR KIT KIT GNAI2 GNAI2 CREB3L3 CREB3L3 NRAS NRAS MAP2K2 MAP2K2 GNAI3 GNAI3 WNT2B WNT2B WNT3A WNT3A WNT9A WNT9A HRAS HRAS WNT8A WNT8A TCF7L2 TCF7L2 PRKACB PRKACB FZD6 FZD6 EDN1 EDN1 PLCB3 PLCB3 WNT4 WNT4 TCF7L1 TCF7L1 ADCY5 ADCY5 WNT9B WNT9B WNT3 WNT3 TYRP1 TYRP1 WNT16 WNT16 CREB3L2 CREB3L2 CREB3L4 CREB3L4 ADCY6 ADCY6 WNT10B WNT10B WNT1 WNT1 FZD2 FZD2 ADCY4 ADCY4 PLCB2 PLCB2 CREB3L1 CREB3L1 PRKCG PRKCG CREBBP CREBBP ADCY9 ADCY9 GSK3B GSK3B PRKACA PRKACA LOC103018216 LOC103018216 LOC103004158 LOC103004158 PRKCA PRKCA EDNRB EDNRB PRKCB PRKCB MAPK3 MAPK3 FZD9 FZD9 GNAI1 GNAI1 WNT8B WNT8B ADCY1 ADCY1 WNT10A WNT10A CAMK2A CAMK2A ADCY8 ADCY8 WNT7B WNT7B CALM2 CALM2 FZD7 FZD7 LEF1 LEF1 ADCY3 ADCY3 ADCY2 ADCY2 MITF MITF RAF1 RAF1 LOC103001360 LOC103001360 FZD3 FZD3 ASIP ASIP CTNNB1 CTNNB1 WNT11 WNT11 KRAS KRAS WNT2 WNT2 DVL3 DVL3 FZD1 FZD1 MAPK1 MAPK1 DCT DCT CREB3 CREB3 FZD10 FZD10 CREB1 CREB1 FZD4 FZD4 LOC103016619 LOC103016619 GNAS GNAS DVL1 DVL1 CAMK2B CAMK2B EP300 EP300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
CALML4Calmodulin-like protein 4. (153 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (302 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
TYRTyrosinase. (530 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (457 aa)
NRASGTPase NRas. (189 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (455 aa)
HRASGTPase HRas isoform X1. (196 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (515 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
EDN1Endothelin-1. (202 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
TCF7L1Transcription factor 7-like 1 isoform X1. (439 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (395 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1220 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CREBBPCREB-binding protein isoform X1. (2444 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC103018216Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
LOC103004158Neuroendocrine secretory protein 55-like. (244 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (408 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
ADCY1Adenylate cyclase type 1 isoform X1. (907 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (535 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (972 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ASIPAgouti-signaling protein. (171 aa)
CTNNB1Catenin beta-1. (767 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
KRASGTPase KRas isoform X3. (227 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3. (719 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
DCTL-dopachrome tautomerase isoform X1. (554 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X1. (371 aa)
FZD10LOW QUALITY PROTEIN: frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (578 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
FZD4LOW QUALITY PROTEIN: frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
LOC103016619Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (253 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
DVL1LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-1. (681 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (501 aa)
EP300Histone acetyltransferase p300. (2445 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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