STRINGSTRING
PLCB4 PLCB4 PLCB1 PLCB1 PRKG2 PRKG2 CALML4 CALML4 ATP2B1 ATP2B1 ATP2B4 ATP2B4 ATP1B2 ATP1B2 KCNMA1 KCNMA1 VAMP2 VAMP2 CD38 CD38 BST1 BST1 ADCY7 ADCY7 KCNN4 KCNN4 LOC103016277 LOC103016277 LOC103020647 LOC103020647 ATP1A1 ATP1A1 SLC9A1 SLC9A1 CHRM3 CHRM3 MUC5B MUC5B LOC103005600 LOC103005600 BEST2 BEST2 ATP1B1 ATP1B1 PRKACB PRKACB ADRB1 ADRB1 PLCB3 PLCB3 ADCY5 ADCY5 LPO LPO LOC103009700 LOC103009700 ATP1B4 ATP1B4 ADCY6 ADCY6 AQP5 AQP5 ADCY4 ADCY4 RYR3 RYR3 PLCB2 PLCB2 PRKCG PRKCG ADCY9 ADCY9 PRKACA PRKACA LOC103018216 LOC103018216 GUCY1A2 GUCY1A2 PRKG1 PRKG1 GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 TRPV6 TRPV6 LOC103004158 LOC103004158 PRKCA PRKCA PRKCB PRKCB ITPR3 ITPR3 ADCY1 ADCY1 LOC103010320 LOC103010320 SLC12A2 SLC12A2 ADRB2 ADRB2 ADCY8 ADCY8 CALM2 CALM2 ADCY3 ADCY3 ADCY2 ADCY2 ITPR1 ITPR1 ADRA1A ADRA1A ITPR2 ITPR2 FXYD2 FXYD2 ATP1B3 ATP1B3 LYZ LYZ ADRA1D ADRA1D LOC103016278 LOC103016278 ATP1A3 ATP1A3 ADRB3 ADRB3 ADRA1B ADRA1B LOC103005321 LOC103005321 SLC4A2 SLC4A2 ATP2B3 ATP2B3 GNAS GNAS NOS1 NOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1258 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
CALML4Calmodulin-like protein 4. (153 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X11. (1230 aa)
VAMP2Vesicle-associated membrane protein 2. (164 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (291 aa)
BST1ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (357 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (428 aa)
LOC103016277Cathelicidin-3-like. (162 aa)
LOC103020647Alpha-amylase. (511 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
MUC5BLOW QUALITY PROTEIN: mucin-5B. (4551 aa)
LOC103005600Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (508 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ADRB1Beta-1 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (526 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
LPOLactoperoxidase isoform X1. (712 aa)
LOC103009700Protegrin-5-like. (140 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1220 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
RYR3LOW QUALITY PROTEIN: ryanodine receptor 3. (4927 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1131 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC103018216Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (329 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (550 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6 isoform X3; Belongs to the transient receptor (TC 1.A.4) family. (721 aa)
LOC103004158Neuroendocrine secretory protein 55-like. (244 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ITPR3LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2666 aa)
ADCY1Adenylate cyclase type 1 isoform X1. (907 aa)
LOC103010320Lysozyme-like protein 1; Belongs to the glycosyl hydrolase 22 family. (148 aa)
SLC12A2Solute carrier family 12 member 2. (1143 aa)
ADRB2Beta-2 adrenergic receptor isoform X1. (449 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
CALM2Calmodulin-1; Belongs to the calmodulin family. (149 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (972 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
ADRA1Aalpha-1A adrenergic receptor isoform X1. (466 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (102 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (266 aa)
LYZLysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (168 aa)
ADRA1Dalpha-1D adrenergic receptor. (459 aa)
LOC103016278Cathelicidin-6-like. (173 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1014 aa)
ADRB3LOW QUALITY PROTEIN: beta-3 adrenergic receptor. (423 aa)
ADRA1Balpha-1B adrenergic receptor. (326 aa)
LOC103005321Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
SLC4A2Anion exchange protein. (1259 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1168 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1007 aa)
NOS1LOW QUALITY PROTEIN: nitric oxide synthase, brain. (1590 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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